(Q35603241)

9 August 2017

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title

Harnessing the therapeutic potential of mesenchymal stem cells in multiple sclerosis (English)

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9 August 2017

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mesenchymal stem cell

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3

Amit Bar-Or

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9 August 2017

Peter J Darlington

1

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9 August 2017

Marie-Noëlle Boivin

series ordinal

2

1 reference

9 August 2017

publication date

1 September 2011

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Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders

9 August 2017

published in

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9 August 2017

volume

11

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9 August 2017

issue

9

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9 August 2017

page(s)

1295-1303

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Concise review: Bone marrow for the treatment of spinal cord injury: mechanisms and clinical applications

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Mesenchymal stem cells for the treatment of multiple sclerosis and other neurological diseases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Mechanisms of cellular therapy in respiratory diseases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Neuroprotective features of mesenchymal stem cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Mesenchymal stem cells and autoimmune diseases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

The mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: an open-label pre-test: post-test study with blinded outcome assessments

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Mapping of the secretome of primary isolates of mammalian cells, stem cells and derived cell lines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Treatment of graft-versus-host-disease with mesenchymal stromal cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Stem cell therapy for cardiac disease.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Bone marrow mesenchymal stem cells: agents of immunomodulation and neuroprotection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Mesenchymal stem cells for multiple sclerosis: does neural differentiation really matter?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Inhibition of immune synapse by altered dendritic cell actin distribution: a new pathway of mesenchymal stem cell immune regulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Fusion between human mesenchymal stem cells and rodent cerebellar Purkinje cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Bone marrow mesenchymal stem cell transplantation in patients with multiple sclerosis: a pilot study

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

A Consensus Statement Addressing Mesenchymal Stem Cell Transplantation for Multiple Sclerosis: It’s Time!

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Immunomodulatory properties of stem cells from human exfoliated deciduous teeth

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Mesenchymal stem cells: a new strategy for immunosuppression and tissue repair

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Mouse bone marrow-derived mesenchymal stromal cells turn activated macrophages into a regulatory-like profile

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Inflammatory cytokine-induced intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in mesenchymal stem cells are critical for immunosuppression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

The therapeutic potential of mesenchymal stem cell transplantation as a treatment for multiple sclerosis: consensus report of the International MSCT Study Group

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Intracerebroventricular transplantation of human mesenchymal stem cells induced to secrete neurotrophic factors attenuates clinical symptoms in a mouse model of multiple sclerosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Mouse mesenchymal stem cells suppress antigen-specific TH cell immunity independent of indoleamine 2,3-dioxygenase 1 (IDO1).

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Microenvironmental considerations in the application of human mesenchymal stem cells in regenerative therapies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Allogeneic mesenchymal stem cells for treatment of experimental autoimmune encephalomyelitis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by inhibiting CD4 Th17 T cells in a CC chemokine ligand 2-dependent manner

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Mesenchymal stem cells suppress B-cell terminal differentiation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

The potential use of stem cells in multiple sclerosis: an overview of the preclinical experience

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Immunomodulation and neuroprotection with mesenchymal bone marrow stem cells (MSCs): a proposed treatment for multiple sclerosis and other neuroimmunological/neurodegenerative diseases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Migration, fate and in vivo imaging of adult stem cells in the CNS.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

The molecular signature of therapeutic mesenchymal stem cells exposes the architecture of the hematopoietic stem cell niche synapse

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Human mesenchymal stem cells modulate B-cell functions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

A paradoxical role for IFN-gamma in the immune properties of mesenchymal stem cells during viral challenge

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Human mesenchymal stem cells modulate allogeneic immune cell responses

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement.

12 July 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Mesenchymal stem cells are capable of homing to the bone marrow of non-human primates following systemic infusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Human bone marrow stromal cell treatment improves neurological functional recovery in EAE mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Neuroprotection and immunomodulation with mesenchymal stem cells in chronic experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Adipose-derived mesenchymal stem cells ameliorate chronic experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Human mesenchymal stem cells infiltrate the spinal cord, reduce demyelination, and localize to white matter lesions in experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Variable behavior and complications of autologous bone marrow mesenchymal stem cells transplanted in experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Galectin-1 and semaphorin-3A are two soluble factors conferring T-cell immunosuppression to bone marrow mesenchymal stem cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Fetal BM-derived mesenchymal stem cells promote the expansion of human Th17 cells, but inhibit the production of Th1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

The effect of mesenchymal stem cells on the viability, proliferation and differentiation of B-lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Effects of mesenchymal stem cells on differentiation, maturation, and function of human monocyte-derived dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Reciprocal interactions between human mesenchymal stem cells and gammadelta T cells or invariant natural killer T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: feasibility, cell migration, and body distribution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Interactions of chemokines and chemokine receptors mediate the migration of mesenchymal stem cells to the impaired site in the brain after hypoglossal nerve injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Mesenchymal stem cells promote oligodendroglial differentiation in hippocampal slice cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Transplantation of mesenchymal stem cells enhances axonal outgrowth and cell survival in an organotypic spinal cord slice culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Mesenchymal stem cells enhance the engraftment and myelinating ability of allogeneic oligodendrocyte progenitors in dysmyelinated mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Does mesenchymal stem cell therapy help multiple sclerosis patients? Report of a pilot study

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Veto-Like Activity of Mesenchymal Stem Cells: Functional Discrimination Between Cellular Responses to Alloantigens and Recall Antigens

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Reciprocal Th1 and Th17 regulation by mesenchymal stem cells: Implication for multiple sclerosis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234364

Regulation of Human Mesenchymal Stem Cell Functions by an Autocrine Loop Involving NAD+ Release and P2Y11-Mediated Signaling

25 September 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERN.11.113

Purinergic stimulation of human mesenchymal stem cells potentiates their chemotactic response to CXCL12 and increases the homing capacity and production of proinflammatory cytokines

21 January 2018

1 reference

12 December 2020

Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates

1 reference

12 December 2020

Differences in mesenchymal stem cell cytokine profiles between MS patients and healthy donors: implication for assessment of disease activity and treatment

1 reference

12 December 2020

Allogeneic mesenchymal stem cells transplantation in treatment of multiple sclerosis

1 reference

12 December 2020

Toll-Like Receptors 3 and 4 Are Expressed by Human Bone Marrow-Derived Mesenchymal Stem Cells and Can Inhibit Their T-Cell Modulatory Activity by Impairing Notch Signaling

1 reference

12 December 2020

Murine bone marrow mesenchymal stem cells cause mature dendritic cells to promote T-cell tolerance

1 reference

12 December 2020

Immunosuppressive effects of mesenchymal stem cells: involvement of HLA-G

1 reference

12 December 2020

Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells

1 reference

12 December 2020

Immunoregulatory function of bone marrow mesenchymal stem cells in EAE depends on their differentiation state and secretion of PGE2

1 reference

12 December 2020

Adult stem cells and multiple sclerosis

1 reference

12 December 2020

Reciprocal effect of mesenchymal stem cell on experimental autoimmune encephalomyelitis is mediated by transforming growth factor-beta and interleukin-6

1 reference

12 December 2020

Identifiers

DOI

10.1586/ERN.11.113

1 reference

9 August 2017

1 reference

9 August 2017

1 reference