(Q35604097)

English

Context-dependent role of angiopoietin-1 inhibition in the suppression of angiogenesis and tumor growth: implications for AMG 386, an angiopoietin-1/2-neutralizing peptibody

scientific article published on October 2010

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scholarly article

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Europe PubMed Central

PubMed publication ID

9 August 2017

Context-dependent role of angiopoietin-1 inhibition in the suppression of angiogenesis and tumor growth: implications for AMG 386, an angiopoietin-1/2-neutralizing peptibody (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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author name string

Angela Coxon

1

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9 August 2017

James Bready

2

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9 August 2017

Hosung Min

3

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9 August 2017

Stephen Kaufman

4

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9 August 2017

Juan Leal

5

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9 August 2017

Dongyin Yu

6

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9 August 2017

Tani Ann Lee

7

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9 August 2017

Ji-Rong Sun

8

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9 August 2017

Juan Estrada

9

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9 August 2017

Brad Bolon

10

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9 August 2017

James McCabe

11

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9 August 2017

Ling Wang

12

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9 August 2017

Karen Rex

13

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9 August 2017

Sean Caenepeel

14

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9 August 2017

Paul Hughes

15

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9 August 2017

David Cordover

16

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9 August 2017

Haejin Kim

17

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9 August 2017

Seog Joon Han

18

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9 August 2017

Mark L Michaels

19

1 reference

Europe PubMed Central

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9 August 2017

Eric Hsu

20

1 reference

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9 August 2017

Grant Shimamoto

21

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9 August 2017

Russell Cattley

22

1 reference

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9 August 2017

Eunju Hurh

23

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9 August 2017

Linh Nguyen

24

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9 August 2017

Shao Xiong Wang

25

1 reference

Europe PubMed Central

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9 August 2017

Anthony Ndifor

26

1 reference

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9 August 2017

Isaac J Hayward

27

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Europe PubMed Central

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9 August 2017

Beverly L Falcón

28

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Europe PubMed Central

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9 August 2017

Donald M McDonald

29

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Europe PubMed Central

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9 August 2017

Luke Li

30

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Europe PubMed Central

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9 August 2017

Tom Boone

31

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Europe PubMed Central

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9 August 2017

Richard Kendall

32

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9 August 2017

Robert Radinsky

33

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Europe PubMed Central

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9 August 2017

Jonathan D Oliner

34

1 reference

Europe PubMed Central

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9 August 2017

publication date

1 October 2010

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Europe PubMed Central

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9 August 2017

Molecular Cancer Therapeutics

1 reference

Europe PubMed Central

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9 August 2017

9

1 reference

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9 August 2017

10

1 reference

Europe PubMed Central

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9 August 2017

2641-2651

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Tyrosine kinase inhibitors of VEGF receptors: clinical issues and remaining questions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Host-derived angiopoietin-2 affects early stages of tumor development and vessel maturation but is dispensable for later stages of tumor growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Broad antitumor activity in breast cancer xenografts by motesanib, a highly selective, oral inhibitor of vascular endothelial growth factor, platelet-derived growth factor, and Kit receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Vascular endothelial growth factor in eye disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

The clinical toxicity profile of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) targeting angiogenesis inhibitors; a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Ranibizumab for neovascular age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

The duality of angiogenesis: implications for therapy of human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

The dynamic roles of angiopoietins in tumor angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Angiopoietin-1 promotes lymphatic sprouting and hyperplasia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Angiopoietin-1 promotes tumor angiogenesis in a rat glioma model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Pericyte recruitment in human corneal angiogenesis: an ultrastructural study with clinicopathological correlation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Angiopoietin-2 expression in breast cancer correlates with lymph node invasion and short survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Orchestration of angiogenesis and arteriovenous contribution by angiopoietins and vascular endothelial growth factor (VEGF).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Activation of the tie2 receptor by angiopoietin-1 enhances tumor vessel maturation and impairs squamous cell carcinoma growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Stabilization of breast cancer xenograft tumour neovasculature by angiopoietin-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Angiopoietin 2 stimulates migration and tube-like structure formation of murine brain capillary endothelial cells through c-Fes and c-Fyn

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Expression and function of angiopoietin-1 in breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Angiopoietin-2 at high concentration can enhance endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Expression of angiogenesis stimulators and inhibitors in human thyroid tumors and correlation with clinical pathological features

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Bacteriophage display and discovery of peptide leads for drug development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

Anticancer strategies involving the vasculature: vascular targeting and the inhibition of angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

12 July 2018

A human monoclonal anti-ANG2 antibody leads to broad antitumor activity in combination with VEGF inhibitors and chemotherapy agents in preclinical models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

25 September 2018

Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

25 September 2018

Angiopoietin 1 causes vessel enlargement, without angiogenic sprouting, during a critical developmental period.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

25 September 2018

Pegaptanib for neovascular age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

25 September 2018

Effects of gene delivery on collateral development in chronic hypoperfusion: diverse effects of angiopoietin-1 versus vascular endothelial growth factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

25 September 2018

Angiopoietin 1 inhibits ocular neovascularization and breakdown of the blood-retinal barrier.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

25 September 2018

Angiopoietin/Tek Interactions Regulate MMP-9 Expression and Retinal Neovascularization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

25 September 2018

Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

25 September 2018

Angiopoietin 1 promotes tumor angiogenesis and tumor vessel plasticity of human cervical cancer in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430860

25 September 2018

Randomized, double-blind, placebo-controlled phase II study of AMG 386 combined with weekly paclitaxel in patients with recurrent ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of angiopoietin-1 expression in tumor cells by an antisense RNA approach inhibited xenograft tumor growth in immunodeficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of interleukin-1 but not tumor necrosis factor suppresses neovascularization in rat models of corneal angiogenesis and adjuvant arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct intramuscular injection of plasmid DNA encoding angiopoietin-1 but not angiopoietin-2 augments revascularization in the rabbit ischemic hindlimb

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple technique for preservation of fixation-sensitive antigens in paraffin-embedded tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of angiopoietin-1 and -2 on tumor growth and angiogenesis in human colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiopoietin-2 is related to tumor angiogenesis in gastric carcinoma: possible in vivo regulation via induction of proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20937592

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1535-7163.MCT-10-0213

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Europe PubMed Central

PubMed publication ID

9 August 2017

release_act272hcyjct7dudzineeludqa

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https://api.fatcat.wiki/v0/release/act272hcyjct7dudzineeludqa

24 November 2022

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Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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