(Q35604234)

9 August 2017

title

Amino-terminal enhancer of split (AES) interacts with the oncoprotein NUP98-HOXA9 and enhances its transforming ability (English)

1 reference

9 August 2017

Nayan J Sarma

1

1 reference

9 August 2017

Nabeel R Yaseen

series ordinal

2

1 reference

9 August 2017

language of work or name

English

0 references

publication date

21 September 2011

1 reference

Journal of Biological Chemistry

9 August 2017

published in

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9 August 2017

volume

286

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9 August 2017

issue

45

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9 August 2017

page(s)

38989-39001

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AML1/ETO induces self-renewal in hematopoietic progenitor cells via the Groucho-related amino-terminal AES protein

9 August 2017

cites work

1 reference

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In Vitro Transformation of Primary Human CD34+ Cells by AML Fusion Oncogenes: Early Gene Expression Profiling Reveals Possible Drug Target in AML

27 July 2018

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Effects of the NUP98-DDX10 oncogene on primary human CD34+ cells: role of a conserved helicase motif

27 July 2018

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Inhibition of CRM1-mediated nuclear export of transcription factors by leukemogenic NUP98 fusion proteins

27 July 2018

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Dissection of the transformation of primary human hematopoietic cells by the oncogene NUP98-HOXA9

27 July 2018

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NUP98-HOX translocations lead to myelodysplastic syndrome in mice and men

27 July 2018

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Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia

27 July 2018

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Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival

27 July 2018

1 reference

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A novel gene, ANKRD28 on 3p25, is fused with NUP98 on 11p15 in a cryptic 3-way translocation of t(3;5;11)(p25;q35;p15) in an adult patient with myelodysplastic syndrome/acute myelogenous leukemia

27 July 2018

1 reference

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Enforced expression of NUP98-HOXA9 in human CD34(+) cells enhances stem cell proliferation

27 July 2018

1 reference

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NUP98-HOXA9 induces long-term proliferation and blocks differentiation of primary human CD34+ hematopoietic cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

NUP98 rearrangements in hematopoietic malignancies: a study of the Groupe Francophone de Cytogénétique Hématologique.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Identification of NUP98 abnormalities in acute leukemia: JARID1A (12p13) as a new partner gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Mammalian Groucho homologs: redundancy or specificity?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

HOXA9 activates transcription of the gene encoding gp91Phox during myeloid differentiation.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

The proline-rich homeodomain protein recruits members of the Groucho/Transducin-like enhancer of split protein family to co-repress transcription in hematopoietic cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Groucho homologue Grg5 interacts with the transcription factor Runx2-Cbfa1 and modulates its activity during postnatal growth in mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Increasing specificity in high-throughput yeast two-hybrid experiments

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

The Oncogene Nup98-HOXA9 Induces Gene Transcription in Myeloid Cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Erythroid gene suppression by NF-kappa B.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Nup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

The three-dimensional structure of the autoproteolytic, nuclear pore-targeting domain of the human nucleoporin Nup98

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Nup98 is a mobile nucleoporin with transcription-dependent dynamics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Caenorhabditis elegans unc-37/groucho interacts genetically with components of the transcriptional mediator complex

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Transcriptional repression: the long and the short of it.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Inhibition of androgen receptor-mediated transcription by amino-terminal enhancer of split

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

The nucleoporin Nup98 associates with the intranuclear filamentous protein network of TPR.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

PRH represses transcription in hematopoietic cells by at least two independent mechanisms

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Transducin-like enhancer of split proteins, the human homologs of Drosophila groucho, interact with hepatic nuclear factor 3beta

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila development

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Nup153 is an M9-containing mobile nucleoporin with a novel Ran-binding domain

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Groucho proteins: transcriptional corepressors for specific subsets of DNA-binding transcription factors in vertebrates and invertebrates

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

NF-kappaB transcription factors are involved in normal erythropoiesis.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Two distinct types of repression domain in engrailed: one interacts with the groucho corepressor and is preferentially active on integrated target genes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Conversion of dorsal from an activator to a repressor by the global corepressor Groucho

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

The vertebrate GLFG nucleoporin, Nup98, is an essential component of multiple RNA export pathways

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Products of the grg (Groucho-related gene) family can dimerize through the amino-terminal Q domain

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Reconstituted nuclei depleted of a vertebrate GLFG nuclear pore protein, p97, import but are defective in nuclear growth and replication

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234724

Flexible gates: dynamic topologies and functions for FG nucleoporins in nucleocytoplasmic transport

27 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

Characterization of 6q abnormalities in childhood acute myeloid leukemia and identification of a novel t(6;11)(q24.1;p15.5) resulting in a NUP98-C6orf80 fusion in a case of acute megakaryoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

NUP98 is fused to topoisomerase (DNA) IIbeta 180 kDa (TOP2B) in a patient with acute myeloid leukemia with a new t(3;11)(p24;p15).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

Fusion of NUP98 and the SET binding protein 1 (SETBP1) gene in a paediatric acute T cell lymphoblastic leukaemia with t(11;18)(p15;q12).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

Clonal evolution with inv(11)(p15q22) and NUP98/DDX10 fusion gene in imatinib-resistant chronic myelogenous leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

NUP98-MLL fusion in human acute myeloblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

Trans-repressive effect of NUP98-PMX1 on PMX1-regulated c-FOS gene through recruitment of histone deacetylase 1 by FG repeats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

The mobile FG nucleoporin Nup98 is a cofactor for Crm1-dependent protein export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

Carrier-independent nuclear import of the transcription factor PU.1 via RanGTP-stimulated binding to Nup153.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

Inhibition of nuclear factor-kappaB-mediated transcription by association with the amino-terminal enhancer of split, a Groucho-related protein lacking WD40 repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

Modularity within the architecture of the nuclear pore complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

Drosophila Tcf and Groucho interact to repress Wingless signalling activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

Cloning and developmental expression of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

Distinct functional domains within nucleoporins Nup153 and Nup98 mediate transcription-dependent mobility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

Epigenetic inactivation of the Groucho homologue gene TLE1 in hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

NUP98–HMGB3: a novel oncogenic fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.297952

t(3;11)(q12;p15)/NUP98-LOC348801 fusion transcript in acute myeloid leukemia

21 January 2018

1 reference

12 December 2020

Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retroviral co-expression of Hoxa9 and Meis1

1 reference

12 December 2020

A novel NUP98-PHF23 fusion resulting from a cryptic translocation t(11;17)(p15;p13) in acute myeloid leukemia

1 reference

12 December 2020

A new fusion gene NUP98-IQCG identified in an acute T-lymphoid/myeloid leukemia with a t(3;11)(q29q13;p15)del(3)(q29) translocation

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.297952

1 reference

9 August 2017

1 reference

9 August 2017

1 reference