(Q35604434)

9 August 2017

title

Generation of N-ethyl-N-nitrosourea (ENU) diabetes models in mice demonstrates genotype-specific action of glucokinase activators (English)

1 reference

9 August 2017

Deborah Fenner

1

1 reference

9 August 2017

Stella Odili

2

1 reference

9 August 2017

Hee-Kyung Hong

3

1 reference

9 August 2017

Yumiko Kobayashi

4

1 reference

9 August 2017

Akira Kohsaka

5

1 reference

9 August 2017

Sandra M Siepka

6

1 reference

9 August 2017

Martha H Vitaterna

7

1 reference

9 August 2017

Pan Chen

8

1 reference

9 August 2017

Bogumil Zelent

9

1 reference

9 August 2017

Joseph Grimsby

10

1 reference

9 August 2017

Joseph S Takahashi

11

1 reference

9 August 2017

Franz M Matschinsky

12

1 reference

9 August 2017

Joseph Bass

13

1 reference

9 August 2017

language of work or name

English

0 references

publication date

15 September 2011

1 reference

Journal of Biological Chemistry

9 August 2017

published in

1 reference

9 August 2017

volume

286

1 reference

9 August 2017

issue

45

1 reference

9 August 2017

page(s)

39560-39572

1 reference

Mutational analysis of allosteric activation and inhibition of glucokinase

9 August 2017

cites work

1 reference

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12 July 2018

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12 July 2018

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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

12 July 2018

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Discovery of candidate disease genes in ENU-induced mouse mutants by large-scale sequencing, including a splice-site mutation in nucleoredoxin

12 July 2018

1 reference

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Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

12 July 2018

1 reference

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Insulin gene mutations as a cause of permanent neonatal diabetes

12 July 2018

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12 July 2018

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Mutational pattern and frequency of induced nucleotide changes in mouse ENU mutagenesis

12 July 2018

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Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

12 July 2018

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A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

12 July 2018

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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

12 July 2018

1 reference

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Glucokinase thermolability and hepatic regulatory protein binding are essential factors for predicting the blood glucose phenotype of missense mutations

12 July 2018

1 reference

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A genome-wide association study identifies novel risk loci for type 2 diabetes

12 July 2018

1 reference

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Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance.

12 July 2018

1 reference

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12 July 2018

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Efficient gene-driven germ-line point mutagenesis of C57BL/6J mice

12 July 2018

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Molecular characterization of ENU mouse mutagenesis and archives

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234779

Efficient and fast targeted production of murine models based on ENU mutagenesis

12 July 2018

1 reference

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Mutation rate and predicted phenotypic target sizes in ethylnitrosourea-treated mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234779

Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase

12 July 2018

1 reference

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Glucokinase (GCK) mutations in hyper- and hypoglycemia: Maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemia of infancy

12 July 2018

1 reference

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Characterization of glucokinase regulatory protein-deficient mice

12 July 2018

1 reference

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12 July 2018

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1 reference

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Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234779

Glucokinase regulatory protein is essential for the proper subcellular localisation of liver glucokinase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234779

Cell-biological assessment of human glucokinase mutants causing maturity-onset diabetes of the young type 2 (MODY-2) or glucokinase-linked hyperinsulinaemia (GK-HI).

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234779

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

12 July 2018

1 reference

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Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

12 July 2018

1 reference

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Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)

12 July 2018

1 reference

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Amino acid conservation in animal glucokinases. Identification of residues implicated in the interaction with the regulatory protein

12 July 2018

1 reference

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Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose

12 July 2018

1 reference

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Animal model for maturity-onset diabetes of the young generated by disruption of the mouse glucokinase gene

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234779

Variable effects of maturity-onset-diabetes-of-youth (MODY)-associated glucokinase mutations on substrate interactions and stability of the enzyme

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234779

Transgenic knockouts reveal a critical requirement for pancreatic beta cell glucokinase in maintaining glucose homeostasis

12 July 2018

1 reference

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12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234779

Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234779

Human pancreatic beta-cell glucokinase: cDNA sequence and localization of the polymorphic gene to chromosome 7, band p 13

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234779

Linkage of type 2 diabetes to the glucokinase gene

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234779

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus

12 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269100

Allosteric activators of glucokinase: potential role in diabetes therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269100

Insights into the structure and regulation of glucokinase from a novel mutation (V62M), which causes maturity-onset diabetes of the young

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269100

Identification and characterization of the ATP-binding site in human pancreatic glucokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269100

Effect of high-fat diet on glucose homeostasis and gene expression in glucokinase knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269100

Impact of small-molecule glucokinase activator on glucose metabolism and beta-cell mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269100

Establishment of liver specific glucokinase gene knockout mice: a new animal model for screening anti-diabetic drugs.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234779

25 September 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269100

PI3Kγ Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269100

Dominant-Negative Effects of a Novel Mutated Ins2 Allele Causes Early-Onset Diabetes and Severe -Cell Loss in Munich Ins2C95S Mutant Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269100

Differential regulation of glucokinase activity in pancreatic islets and liver of the rat

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21921030

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21921030

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.269100

1 reference

9 August 2017

1 reference

9 August 2017

1 reference