(Q45242050)

11 December 2017

title

Insights into the structure and regulation of glucokinase from a novel mutation (V62M), which causes maturity-onset diabetes of the young (English)

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11 December 2017

9

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11 December 2017

Fabrizio Barbetti

16

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Anna Gloyn

Anna L Gloyn

1

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Emile Van Schaftingen

Emile van Schaftingen

14

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Charles A Stanley

Charles A Stanley

12

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Sian Ellard

Sian Ellard

21

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Andrew Tym Hattersley

22

Andrew T Hattersley

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11 December 2017

Stella Odili

2

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11 December 2017

Dorothy Zelent

3

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11 December 2017

Carol Buettger

4

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11 December 2017

Harriet A J Castleden

5

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11 December 2017

Anna M Steele

6

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11 December 2017

Amanda Stride

7

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11 December 2017

Chyio Shiota

8

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11 December 2017

Renata Lorini

10

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11 December 2017

Giuseppe d'Annunzio

11

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11 December 2017

Jae Kwagh

13

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11 December 2017

Maria Veiga-da-Cunha

15

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11 December 2017

Pete Dunten

17

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11 December 2017

Yi Han

18

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11 December 2017

Joseph Grimsby

19

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11 December 2017

Rebecca Taub

20

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11 December 2017

Franz M Matschinsky

23

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11 December 2017

language of work or name

English

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publication date

25 January 2005

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Journal of Biological Chemistry

11 December 2017

published in

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11 December 2017

volume

280

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11 December 2017

issue

14

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11 December 2017

page(s)

14105-14113

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Glucose-dependent insulin release from genetically engineered K cells

11 December 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M413146200

Glucose sensing in pancreatic beta-cells: a model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

A protein from rat liver confers to glucokinase the property of being antagonistically regulated by fructose 6-phosphate and fructose 1-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Regulation of hepatic glucose metabolism by translocation of glucokinase between the nucleus and the cytoplasm in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Characterization of glucokinase regulatory protein-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Evidence that glucokinase regulatory protein is expressed and interacts with glucokinase in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

A functional link between glucokinase binding to insulin granules and conformational alterations in response to glucose and insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Glucokinase is an integral component of the insulin granules in glucose-responsive insulin secretory cells and does not translocate during glucose stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Linkage of type 2 diabetes to the glucokinase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Glucokinase (GCK) mutations in hyper- and hypoglycemia: Maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemia of infancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Regulation of pancreatic beta-cell glucokinase: from basics to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Familial hyperinsulinism caused by an activating glucokinase mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Severe persistent hyperinsulinemic hypoglycemia due to a de novo glucokinase mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Structural model of human glucokinase in complex with glucose and ATP: implications for the mutants that cause hypo- and hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Allosteric activators of glucokinase: potential role in diabetes therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Human glucokinase gene: isolation, characterization, and identification of two missense mutations linked to early-onset non-insulin-dependent (type 2) diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Variable effects of maturity-onset-diabetes-of-youth (MODY)-associated glucokinase mutations on substrate interactions and stability of the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Effect of mutations on the sensitivity of human beta-cell glucokinase to liver regulatory protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Structural instability of mutant beta-cell glucokinase: implications for the molecular pathogenesis of maturity-onset diabetes of the young (type-2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

The genetic abnormality in the beta cell determines the response to an oral glucose load

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Amino acid conservation in animal glucokinases. Identification of residues implicated in the interaction with the regulatory protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Competitive inhibition of liver glucokinase by its regulatory protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Mutations in the glucokinase regulatory protein gene in 2p23 in obese French caucasians

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

Characterization of glucokinase-binding protein epitopes by a phage-displayed peptide library. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel interaction partner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

A novel cytosolic dual specificity phosphatase, interacting with glucokinase, increases glucose phosphorylation rate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413146200

21 January 2018

Identifiers

DOI

10.1074/JBC.M413146200

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11 December 2017

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