(Q44052572)

29 November 2017

title

A functional link between glucokinase binding to insulin granules and conformational alterations in response to glucose and insulin (English)

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29 November 2017

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2

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29 November 2017

Mark A Rizzo

1

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29 November 2017

Peter F Drain

series ordinal

3

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29 November 2017

David W Piston

series ordinal

4

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29 November 2017

language of work or name

English

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publication date

5 July 2002

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Journal of Biological Chemistry

29 November 2017

published in

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29 November 2017

volume

277

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29 November 2017

issue

37

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29 November 2017

page(s)

34168-34175

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Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities.

29 November 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M112478200

Modulation of glucose responsiveness of insulinoma beta-cells by graded overexpression of glucokinase

21 January 2018

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Familial hyperinsulinism caused by an activating glucokinase mutation

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Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis

21 January 2018

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Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

21 January 2018

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Concordant Glucose Induction of Glucokinase, Glucose Usage, and Glucose-Stimulated Insulin Release in Pancreatic Islets Maintained in Organ Culture

21 January 2018

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Increased catalytic activity of glucokinase in isolated islets from hyperinsulinemic rats

21 January 2018

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Regulatory effects of glucose on the catalytic activity and cellular content of glucokinase in the pancreatic beta cell. Study using cultured rat islets

21 January 2018

1 reference

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Glucokinase is concentrated in insulin-secretory granules of pancreatic B-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112478200

Subcellular localization, mobility, and kinetic activity of glucokinase in glucose-responsive insulin-secreting cells

21 January 2018

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Translocation and reversible localization of signaling proteins: a dynamic future for signal transduction

21 January 2018

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Intracellular binding of glucokinase in hepatocytes and translocation by glucose, fructose and insulin

21 January 2018

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Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase

21 January 2018

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Energy-dependent intracellular translocation of glucokinase in rat pancreatic islets

21 January 2018

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From fixed to FRAP: measuring protein mobility and activity in living cells

21 January 2018

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Using GFP in FRET-based applications

21 January 2018

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Imaging into the future: visualizing gene expression and protein interactions with fluorescent proteins.

21 January 2018

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Receptor-mediated activation of heterotrimeric G-proteins in living cells

21 January 2018

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Adenovirus-mediated knockout of a conditional glucokinase gene in isolated pancreatic islets reveals an essential role for proximal metabolic coupling events in glucose-stimulated insulin secretion

21 January 2018

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Heterogeneous expression of glucokinase among pancreatic beta cells

21 January 2018

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Imaging secretory vesicles by fluorescent protein insertion in propeptide rather than mature secreted peptide

21 January 2018

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Probing the structure of cytoplasm

21 January 2018

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Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

21 January 2018

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Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta -cells.

21 January 2018

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Desensitization of glucagon-like peptide 1 receptors in insulin-secreting beta TC3 cells: role of PKA-independent mechanisms

21 January 2018

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Glucose stimulates voltage- and calcium-dependent inositol trisphosphate production and intracellular calcium mobilization in insulin-secreting beta TC3 cells

21 January 2018

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Insulin targeting to the regulated secretory pathway after fusion with green fluorescent protein and firefly luciferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112478200

Secretory-granule dynamics visualized in vivo with a phogrin-green fluorescent protein chimaera

21 January 2018

1 reference

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Imaging exocytosis of single insulin secretory granules with evanescent wave microscopy: distinct behavior of granule motion in biphasic insulin release

21 January 2018

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Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin

21 January 2018

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FRET-based in vivo Ca2+ imaging by a new calmodulin-GFP fusion molecule.

21 January 2018

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Role of metallothionein in nitric oxide signaling as revealed by a green fluorescent fusion protein

21 January 2018

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Detection of programmed cell death using fluorescence energy transfer

21 January 2018

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Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer

21 January 2018

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Fluorescence resonance energy transfer between blue-emitting and red-shifted excitation derivatives of the green fluorescent protein.

21 January 2018

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Novel mutant green fluorescent protein protease substrates reveal the activation of specific caspases during apoptosis.

21 January 2018

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Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M112478200

Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112478200

Metabolic coupling factors in pancreatic beta-cell signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112478200

Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells

21 January 2018

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New perspectives into the molecular pathogenesis and treatment of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112478200

21 January 2018

Identifiers

DOI

10.1074/JBC.M112478200

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29 November 2017

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