Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q35604849)
Watch
English
Fatty acids suppress autophagic turnover in β-cells
scientific article published on 21 August 2011
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3234912
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
title
Fatty acids suppress autophagic turnover in β-cells
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3234912
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
main subject
autophagy
0 references
fatty acid
0 references
author
Jakob D Wikstrom
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3234912
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
author name string
Guy Las
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3234912
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
Sam B Serada
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3234912
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
Gilad Twig
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3234912
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
Orian S Shirihai
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
3234912
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
language of work or name
English
0 references
publication date
21 August 2011
1 reference
stated in
Europe PubMed Central
PMC publication ID
3234912
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
published in
Journal of Biological Chemistry
1 reference
stated in
Europe PubMed Central
PMC publication ID
3234912
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
volume
286
1 reference
stated in
Europe PubMed Central
PMC publication ID
3234912
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
issue
49
1 reference
stated in
Europe PubMed Central
PMC publication ID
3234912
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
page(s)
42534-42544
1 reference
stated in
Europe PubMed Central
PMC publication ID
3234912
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
cites work
Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Altered lipid content inhibits autophagic vesicular fusion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Regulation mechanisms and signaling pathways of autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Mitochondrial networking protects beta-cells from nutrient-induced apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Autophagy regulates lipid metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Glucose amplifies fatty acid-induced endoplasmic reticulum stress in pancreatic beta-cells via activation of mTORC1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Assessing mammalian autophagy by WIPI-1/Atg18 puncta formation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Autophagy in the Pathogenesis of Disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Limited mitochondrial permeabilization is an early manifestation of palmitate-induced lipotoxicity in pancreatic beta-cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Glucolipotoxicity: fuel excess and beta-cell dysfunction.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Autophagy: basic principles and relevance to disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Ubiquitinated-protein aggregates form in pancreatic beta-cells during diabetes-induced oxidative stress and are regulated by autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Involvement of mtDNA damage in free fatty acid-induced apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Mitochondrial functional state in clonal pancreatic beta-cells exposed to free fatty acids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Acidification of endocytic vesicles by an ATP-dependent proton pump
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
12 July 2018
Free fatty acids stimulate autophagy in pancreatic β-cells via JNK pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
25 September 2018
Autophagy in human type 2 diabetes pancreatic beta cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
25 September 2018
Flow cytometric analysis of autophagy in living mammalian cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
25 September 2018
Assaying of autophagic protein degradation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
25 September 2018
Monitoring autophagy in mammalian cultured cells through the dynamics of LC3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
25 September 2018
Protective role of autophagy in palmitate-induced INS-1 beta-cell death.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
25 September 2018
Utilizing flow cytometry to monitor autophagy in living mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
25 September 2018
Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
25 September 2018
A convenient one-step extraction of cellular ATP using boiling water for the luciferin-luciferase assay of ATP.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
25 September 2018
Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
25 September 2018
Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234912
retrieved
25 September 2018
-Cell Mitochondria Exhibit Membrane Potential Heterogeneity That Can Be Altered by Stimulatory or Toxic Fuel Levels
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M111.242412
retrieved
21 January 2018
Identifiers
DOI
10.1074/JBC.M111.242412
1 reference
stated in
Europe PubMed Central
PMC publication ID
3234912
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
PMC publication ID
3234912
1 reference
stated in
Europe PubMed Central
PMC publication ID
3234912
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
PubMed publication ID
21859708
1 reference
stated in
Europe PubMed Central
PMC publication ID
3234912
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 February 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit