(Q35604861)

9 August 2017

title

γ-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1. (English)

1 reference

9 August 2017

0 references

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9

Maria B Grant

1 reference

9 August 2017

Jun Cai

1

1 reference

9 August 2017

Zhijuan Chen

2

1 reference

9 August 2017

Qing Ruan

3

1 reference

9 August 2017

Song Han

4

1 reference

9 August 2017

Li Liu

5

1 reference

9 August 2017

Xiaoping Qi

6

1 reference

9 August 2017

Sanford L Boye

7

1 reference

9 August 2017

William W Hauswirth

8

1 reference

9 August 2017

Michael E Boulton

10

1 reference

9 August 2017

language of work or name

English

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publication date

20 October 2011

1 reference

Journal of Biological Chemistry

9 August 2017

published in

1 reference

9 August 2017

volume

286

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9 August 2017

issue

49

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9 August 2017

page(s)

42514-42523

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PEDF regulates vascular permeability by a γ-secretase-mediated pathway

9 August 2017

cites work

1 reference

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When signaling kinases meet histones and histone modifiers in the nucleus

12 July 2018

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Retracted: Placenta Growth Factor-1 Exerts Time-Dependent Stabilization of Adherens Junctions Following VEGF-Induced Vascular Permeability

12 July 2018

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High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines.

12 July 2018

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Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations

12 July 2018

1 reference

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Proteases and sFlt-1 release in the human placenta

12 July 2018

1 reference

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Aph-1 associates directly with full-length and C-terminal fragments of gamma-secretase substrates

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

Down-regulation of the met receptor tyrosine kinase by presenilin-dependent regulated intramembrane proteolysis

12 July 2018

1 reference

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Identification of ligand-induced proteolytic cleavage and ectodomain shedding of VEGFR-1/FLT1 in leukemic cancer cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

gamma-Secretase in biology and medicine

12 July 2018

1 reference

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Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

12 July 2018

1 reference

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ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

gamma-Secretase: a multifaceted regulator of angiogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

The age of crosstalk: phosphorylation, ubiquitination, and beyond

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

Presenilin 1 regulates epidermal growth factor receptor turnover and signaling in the endosomal-lysosomal pathway.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

VEGF receptor signalling - in control of vascular function

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

VEGFR-1 and VEGFR-2: two non-identical twins with a unique physiognomy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

Syntaxin 5 interacts with presenilin holoproteins, but not with their N- or C-terminal fragments, and affects beta-amyloid peptide production

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

Presenilin-dependent "gamma-secretase" processing of deleted in colorectal cancer (DCC)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

The role of presenilin cofactors in the gamma-secretase complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

PEN-2 is an integral component of the gamma-secretase complex required for coordinated expression of presenilin and nicastrin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

kuzbanian-mediated cleavage of Drosophila Notch

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

Presenilins interact with Rab11, a small GTPase involved in the regulation of vesicular transport

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234916

Inhibition of vitreoretinal VEGF elevation and blood-retinal barrier breakdown in streptozotocin-induced diabetic rats by brimonidine

12 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.296590

Mammalian SH2-containing protein tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.296590

Expression of placenta growth factor is regulated by both VEGF and hyperglycaemia via VEGFR-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.296590

Rab6 membrane association is dependent of Presenilin 1 and cellular phosphorylation events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.296590

Mutant presenilin (A260V) affects Rab8 in PC12D cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.296590

Identification of syntaxin 1A as a novel binding protein for presenilin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.296590

Presenilin/gamma-secretase-mediated cleavage regulates association of leukocyte-common antigen-related (LAR) receptor tyrosine phosphatase with beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.296590

Reconstitution of gamma-secretase by truncated presenilin (PS) fragments revealed that PS C-terminal transmembrane domain is critical for formation of gamma-secretase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.296590

Morphometric evaluation of tumor matrix metalloproteinase 9 predicts survival after surgical resection of adenocarcinoma of the lung

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22016384

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.296590

1 reference

9 August 2017

1 reference

9 August 2017

1 reference