(Q35605923)

9 August 2017

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title

Molecular genetics of Mycobacterium tuberculosis in relation to the discovery of novel drugs and vaccines (English)

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Mycobacterium tuberculosis

9 August 2017

main subject

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2

Valerie Mizrahi

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9 August 2017

Bavesh D Kana

1

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language of work or name

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1 January 2004

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9 August 2017

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9 August 2017

volume

84

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9 August 2017

issue

1-2

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9 August 2017

page(s)

63-75

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Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

9 August 2017

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Recombinant bacillus calmette-guerin (BCG) vaccines expressing the Mycobacterium tuberculosis 30-kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal model

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Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis

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7 January 2021

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New method churns out TB mutants

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Prospects for new interventions in the treatment and prevention of mycobacterial disease

7 January 2021

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Restriction endonuclease mapping and cloning of Mycobacterium fortuitum var. fortuitum plasmid pAL5000

7 January 2021

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Efficient allelic exchange and transposon mutagenesis in Mycobacterium tuberculosis

7 January 2021

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Introduction of foreign DNA into mycobacteria using a shuttle phasmid

7 January 2021

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A novel mycolic acid cyclopropane synthetase is required for cording, persistence, and virulence of Mycobacterium tuberculosis

7 January 2021

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The Mycobacterium tuberculosis pks2 gene encodes the synthase for the hepta- and octamethyl-branched fatty acids required for sulfolipid synthesis

7 January 2021

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Identification and characterization of mycobacteriophage L5 excisionase

7 January 2021

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A novel transposon trap for mycobacteria: isolation and characterization of IS1096

7 January 2021

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Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature-tagged transposon mutagenesis

7 January 2021

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Complex lipid determines tissue-specific replication of Mycobacterium tuberculosis in mice

7 January 2021

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Conditionally replicating mycobacteriophages: a system for transposon delivery to Mycobacterium tuberculosis

7 January 2021

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Construction and application of mycobacterial reporter transposons

7 January 2021

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Simultaneous identification of bacterial virulence genes by negative selection.

7 January 2021

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Microbial pathogenesis of Mycobacterium tuberculosis: dawn of a discipline

7 January 2021

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Analysis of the phthiocerol dimycocerosate locus of Mycobacterium tuberculosis. Evidence that this lipid is involved in the cell wall permeability barrier

7 January 2021

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Efficient transposition in mycobacteria: construction of Mycobacterium smegmatis insertional mutant libraries

7 January 2021

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In vivo transposition of mariner-based elements in enteric bacteria and mycobacteria.

7 January 2021

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In vitro transposition of Tn552: a tool for DNA sequencing and mutagenesis

7 January 2021

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Identification of genes encoding exported Mycobacterium tuberculosis proteins using a Tn552'phoA in vitro transposition system

7 January 2021

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Construction by homologous recombination and phenotypic characterization of a DNA polymerase domain polA mutant of Mycobacterium smegmatis

7 January 2021

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rpsL+: a dominant selectable marker for gene replacement in mycobacteria.

7 January 2021

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The uraA locus and homologous recombination in Mycobacterium bovis BCG.

7 January 2021

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Insertional mutagenesis and illegitimate recombination in mycobacteria

7 January 2021

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The urease locus of Mycobacterium tuberculosis and its utilization for the demonstration of allelic exchange in Mycobacterium bovis bacillus Calmette-Guérin

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Production of avirulent Mycobacterium bovis strains by illegitimate recombination with deoxyribonucleic acid fragments containing an interrupted ahpC gene

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Allelic exchange in Mycobacterium tuberculosis with long linear recombination substrates

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Novel structure of the recA locus of Mycobacterium tuberculosis implies processing of the gene product

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Recombination in mycobacteria

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Targeted replacement of the mycocerosic acid synthase gene in Mycobacterium bovis BCG produces a mutant that lacks mycosides

7 January 2021

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Gene replacement through homologous recombination in Mycobacterium intracellulare

7 January 2021

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Efficient homologous recombination in fast-growing and slow-growing mycobacteria

7 January 2021

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Gene replacement by homologous recombination in Mycobacterium bovis BCG

7 January 2021

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Investigation of mycobacterial recA function: protein introns in the RecA of pathogenic mycobacteria do not affect competency for homologous recombination

7 January 2021

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Construction and complementation of a recA deletion mutant of Mycobacterium smegmatis reveals that the intein in Mycobacterium tuberculosis recA does not affect RecA function

7 January 2021

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Electroporation at elevated temperatures substantially improves transformation efficiency of slow-growing mycobacteria

7 January 2021

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Generation of unmarked directed mutations in mycobacteria, using sucrose counter-selectable suicide vectors

7 January 2021

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Attenuation of virulence by disruption of the Mycobacterium tuberculosis erp gene

7 January 2021

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Enhanced gene replacement in mycobacteria

7 January 2021

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Production of mutants in amino acid biosynthesis genes of Mycobacterium tuberculosis by homologous recombination

7 January 2021

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Use of a flexible cassette method to generate a double unmarked Mycobacterium tuberculosis tlyA plcABC mutant by gene replacement

7 January 2021

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Expression of Mycobacterium smegmatis pyrazinamidase in Mycobacterium tuberculosis confers hypersensitivity to pyrazinamide and related amides

7 January 2021

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The stringent response of Mycobacterium tuberculosis is required for long-term survival

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Auxotrophic vaccines for tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Characterization of auxotrophic mutants of Mycobacterium tuberculosis and their potential as vaccine candidates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Effect of different purine auxotrophic mutations on mouse-virulence of a Vi-positive strain of Salmonella dublin and of two strains of Salmonella typhimurium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Attenuation of and protection induced by a leucine auxotroph of Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Identification of a Mycobacterium bovis BCG auxotrophic mutant that protects guinea pigs against M. bovis and hematogenous spread of Mycobacterium tuberculosis without sensitization to tuberculin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

whmD is an essential mycobacterial gene required for proper septation and cell division

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Biosynthesis of diaminopimelate, the precursor of lysine and a component of peptidoglycan, is an essential function of Mycobacterium smegmatis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

glnE is an essential gene in Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Ribonucleotide reductases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Characterization of two genes encoding the Mycobacterium tuberculosis ribonucleotide reductase small subunit

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Ribonucleotide Reduction in Mycobacterium tuberculosis : Function and Expression of Genes Encoding Class Ib and Class II Ribonucleotide Reductases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Attenuation of virulence in Mycobacterium tuberculosis expressing a constitutively active iron repressor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Overexpression of heat-shock proteins reduces survival of Mycobacterium tuberculosis in the chronic phase of infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

The Mycobacterium tuberculosis cmaA2 gene encodes a mycolic acid trans-cyclopropane synthetase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Cloning and characterization of a bifunctional RelA/SpoT homologue from Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

The rel gene is essential for in vitro growth of Staphylococcus aureus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding α-crystallin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Redundancy of aerobic respiratory chains in bacteria? Routes, reasons and regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Cytochrome bd terminal oxidase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Oxygen depletion induced dormancy in Mycobacterium smegmatis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

DNA repair in Mycobacterium tuberculosis. What have we learnt from the genome sequence?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Anaerobic nitrate reductase (narGHJI) activity of Mycobacterium bovis BCG in vitro and its contribution to virulence in immunodeficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Nitrosated peptides and polyamines as endogenous mutagens in O6-alkylguanine-DNA alkyltransferase deficient cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Generation of an endogenous DNA-methylating agent by nitrosation in Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

DNA alkylation damage as a sensor of nitrosative stress in Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Mycobacterium bovis BCG recA deletion mutant shows increased susceptibility to DNA-damaging agents but wild-type survival in a mouse infection model.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

Comparison of the construction of unmarked deletion mutations in Mycobacterium smegmatis, Mycobacterium bovis bacillus Calmette-Guérin, and Mycobacterium tuberculosis H37Rv by allelic exchange.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

inferred from DOI database lookup

7 January 2021

based on heuristic

Mycobacterial stationary phase induced by low oxygen tension: cell wall thickening and localization of the 16-kilodalton alpha-crystallin homolog.

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

inferred from DOI database lookup

7 January 2021

based on heuristic

Impact of either elevated or decreased levels of cytochrome bd expression on Shigella flexneri virulence

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2003.08.006

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.TUBE.2003.08.006

1 reference

9 August 2017

1 reference