(Q35609022)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25960197%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

title

Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation (English)

1 reference

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7 March 2020

4

1 reference

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7 March 2020

author name string

Jingdong Cheng

1

1 reference

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7 March 2020

Huirong Yang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25960197%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Jian Fang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25960197%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Rui Gong

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25960197%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Ping Wang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25960197%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Ze Li

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25960197%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Yanhui Xu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25960197%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

language of work or name

English

0 references

publication date

11 May 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25960197%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25960197%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25960197%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

page(s)

7023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25960197%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

7 March 2020

copyright license

start time

11 May 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Synergistic re-activation of epigenetically silenced genes by combinatorial inhibition of DNMTs and LSD1 in cancer cells

27 July 2018

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Deubiquitination of Tip60 by USP7 determines the activity of the p53-dependent apoptotic pathway

27 July 2018

1 reference

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DNA methylation: roles in mammalian development

27 July 2018

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Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice.

27 July 2018

1 reference

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Regulation of DNA methyltransferase 1 by interactions and modifications

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase

27 July 2018

1 reference

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A decade of exploring the cancer epigenome - biological and translational implications

27 July 2018

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The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1

27 July 2018

1 reference

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Regulation of expression and activity of DNA (cytosine-5) methyltransferases in mammalian cells

27 July 2018

1 reference

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Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties

27 July 2018

1 reference

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The multifaceted roles of USP7: new therapeutic opportunities

27 July 2018

1 reference

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Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation

27 July 2018

1 reference

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Phenotype and genotype of pancreatic cancer cell lines

27 July 2018

1 reference

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Lysine acetylation targets protein complexes and co-regulates major cellular functions

27 July 2018

1 reference

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Phasercrystallographic software

27 July 2018

1 reference

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DUBs and cancer: the role of deubiquitinating enzymes as oncogenes, non-oncogenes and tumor suppressors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Preclinical evaluation of the antineoplastic action of 5-aza-2'-deoxycytidine and different histone deacetylase inhibitors on human Ewing's sarcoma cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Inhibition of histone deacetylases promotes ubiquitin-dependent proteasomal degradation of DNA methyltransferase 1 in human breast cancer cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

UHRF1 plays a role in maintaining DNA methylation in mammalian cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells

27 July 2018

1 reference

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Further analysis of trials with azacitidine in patients with myelodysplastic syndrome: studies 8421, 8921, and 9221 by the Cancer and Leukemia Group B.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization

27 July 2018

1 reference

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Coot: model-building tools for molecular graphics

27 July 2018

1 reference

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Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach.

27 July 2018

1 reference

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Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP

27 July 2018

1 reference

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Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

27 July 2018

1 reference

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PHENIX: building new software for automated crystallographic structure determination

27 July 2018

1 reference

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DNA methylation patterns and epigenetic memory

27 July 2018

1 reference

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A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein

27 July 2018

1 reference

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M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Regulation of mammalian DNA methyltransferases: a route to new mechanisms

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Significance of DNA methyltransferase-1 and histone deacetylase-1 in pancreatic cancer

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Increased DNA methyltransferase 1 (DNMT1) protein expression in precancerous conditions and ductal carcinomas of the pancreas.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

EUKARYOTIC CYTOSINE METHYLTRANSFERASES

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Preclinical evaluation of antineoplastic activity of inhibitors of DNA methylation (5-aza-2'-deoxycytidine) and histone deacetylation (trichostatin A, depsipeptide) in combination against myeloid leukemic cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432644

Processing of X-ray diffraction data collected in oscillation mode

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS8023

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS8023

Analysis of p16 CDKN2A Methylation and HPV-16 Infection in Oral Mucosal Dysplasia

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25960197

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS8023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25960197%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25960197%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

25960197

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25960197%20AND%20SRC:MED&resulttype=core&format=json