(Q39948774)

15 September 2017

The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network (English)

1 reference

Ubiquitin specific peptidase 7

15 September 2017

1 reference

Phosphatase and tensin homolog

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Julie Teruya-Feldstein

series ordinal

6

object named as

Julie Teruya-Feldstein

0 references

Pier Paolo Pandolfi

series ordinal

7

object named as

Pier Paolo Pandolfi

0 references

Francesco Lo-Coco

series ordinal

5

object named as

Francesco Lo-Coco

1 reference

15 September 2017

1

Min Sup Song

1 reference

15 September 2017

3

Arkaitz Carracedo

1 reference

15 September 2017

2

Leonardo Salmena

1 reference

15 September 2017

4

Ainara Egia

1 reference

15 September 2017

PMCID

3398484

language of work or name

English

0 references

publication date

20 August 2008

1 reference

15 September 2017

1 reference

15 September 2017

455

1 reference

15 September 2017

813-817

1 reference

15 September 2017

7214

1 reference

https://scigraph.springernature.com/pub.10.1038/nature07290

15 September 2017

0 references

cites work

Tenets of PTEN tumor suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Monoubiquitylation promotes mitochondrial p53 translocation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Essential role for nuclear PTEN in maintaining chromosomal integrity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Ubiquitination regulates PTEN nuclear import and tumor suppression

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

PTEN enters the nuclear age.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

The mechanisms of PML-nuclear body formation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Acute promyelocytic leukemia as a paradigm for targeted therapy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

ONCOMINE: a cancer microarray database and integrated data-mining platform

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Tumour suppression: disruption of HAUSP gene stabilizes p53

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Mono- versus polyubiquitination: differential control of p53 fate by Mdm2.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

PTEN: one gene, many syndromes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

PTEN mutational spectra, expression levels, and subcellular localization in microsatellite stable and unstable colorectal cancers

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Epigenetic PTEN silencing in malignant melanomas without PTEN mutation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Protein expression and cellular localization in two prognostic subgroups of diffuse large B-cell lymphoma: higher expression of ZAP70 and PKC-beta II in the non-germinal center group and poor survival in patients deficient in nuclear PTEN.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

SnapShot: PTEN signaling pathways.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398484

Expression and prognostic significance of PTEN product protein in patients with esophageal squamous cell carcinoma

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18716620

12 December 2020

inferred from PubMed ID database lookup

Changing venues for tumour suppression: balancing destruction and localization by monoubiquitylation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18716620

12 December 2020

inferred from PubMed ID database lookup

The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07290

7 January 2021

Critical role for Daxx in regulating Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07290

7 January 2021

PML regulates p53 stability by sequestering Mdm2 to the nucleolus

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07290

7 January 2021

A CK2-dependent mechanism for degradation of the PML tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FNATURE07290

7 January 2021

Identifiers

DOI

10.1038/NATURE07290

1 reference

PMCID

3398484

Dimensions Publication ID

15 September 2017

0 references

1 reference

15 September 2017

1 reference

PMCID

3398484