(Q35616431)

25918394

9 August 2017

title

Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation (English)

1 reference

9 August 2017

1

1 reference

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10 June 2020

Marc Fahrner

5

1 reference

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10 June 2020

Melina Benson

7

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10 June 2020

Sebastian Fuchs

8

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10 June 2020

Stephan Ehl

9

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10 June 2020

Christoph Romanin

10

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10 June 2020

Mitsuhiko Ikura

11

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10 June 2020

Murali Prakriya

12

1 reference

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10 June 2020

Stefan Feske

13

1 reference

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10 June 2020

author name string

Amit Jairaman

2

1 reference

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10 June 2020

Peter B Stathopulos

3

1 reference

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10 June 2020

Martin Muik

4

1 reference

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10 June 2020

Carl Weidinger

6

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10 June 2020

language of work or name

English

0 references

publication date

27 April 2015

1 reference

25918394

Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

published in

1 reference

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10 June 2020

volume

112

1 reference

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10 June 2020

issue

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25918394%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

6206-6211

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25918394%20AND%20SRC:MED&resulttype=core&format=json

Gain-of-Function Mutation in STIM1 (P.R304W) Is Associated with Stormorken Syndrome

10 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

A dominant STIM1 mutation causes Stormorken syndrome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

Activating mutations in STIM1 and ORAI1 cause overlapping syndromes of tubular myopathy and congenital miosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

Initial activation of STIM1, the regulator of store-operated calcium entry

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

Molecular regulation of CRAC channels and their role in lymphocyte function

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

Antiviral and regulatory T cell immunity in a patient with stromal interaction molecule 1 deficiency

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

Immunodeficiency due to defects in store-operated calcium entry

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

Activation of STIM1-Orai1 involves an intramolecular switching mechanism.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

Essential role for the CRAC activation domain in store-dependent oligomerization of STIM1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

Molecular basis of calcium signaling in lymphocytes: STIM and ORAI

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

A basic sequence in STIM1 promotes Ca2+ influx by interacting with the C-terminal acidic coiled coil of Orai1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

STIM1 gates the store-operated calcium channel ORAI1 in vitro

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

SOAR and the polybasic STIM1 domains gate and regulate Orai channels

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

Molecular clustering of STIM1 with Orai1/CRACM1 at the plasma membrane depends dynamically on depletion of Ca2+ stores and on electrostatic interactions.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER-plasma membrane junctions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

STIM1, an essential and conserved component of store-operated Ca2+ channel function

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

A coiled-coil clamp controls both conformation and clustering of stromal interaction molecule 1 (STIM1).

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4434767

Intramolecular shielding maintains the ER Ca²⁺ sensor STIM1 in an inactive conformation

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25918394

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1418852112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25918394%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25918394%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

25918394

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25918394%20AND%20SRC:MED&resulttype=core&format=json