(Q35617678)

9 August 2017

title

A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee (English)

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9 August 2017

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1

Stanley B Cohen

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9 August 2017

Susanna Proudman

2

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9 August 2017

Alan J Kivitz

3

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9 August 2017

Francis X Burch

4

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9 August 2017

John P Donohue

5

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9 August 2017

Deborah Burstein

6

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9 August 2017

Yu-Nien Sun

7

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9 August 2017

Christopher Banfield

8

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9 August 2017

Michael S Vincent

9

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9 August 2017

Liyun Ni

10

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9 August 2017

Debra J Zack

11

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9 August 2017

publication date

29 July 2011

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Arthritis Research and Therapy

9 August 2017

published in

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9 August 2017

volume

13

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9 August 2017

issue

4

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9 August 2017

page(s)

R125

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https://scigraph.springernature.com/pub.10.1186/ar3430

9 August 2017

exact match

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cites work

Role of interleukin-1beta during pain and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239365

Osteoarthritis: a tale of three tissues.

12 July 2018

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Autologous interleukin-1 receptor antagonist improves function and symptoms in osteoarthritis when compared to placebo in a prospective randomized controlled trial

12 July 2018

1 reference

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The role of cytokines in osteoarthritis pathophysiology

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239365

Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239365

Interleukin-1, tumor necrosis factor alpha, and interleukin-17 synergistically up-regulate nitric oxide and prostaglandin E2 production in explants of human osteoarthritic knee menisci

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239365

Potent inhibition of the master chondrogenic factor Sox9 gene by interleukin-1 and tumor necrosis factor-alpha

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239365

In vivo transfer of interleukin-1 receptor antagonist gene in osteoarthritic rabbit knee joints: prevention of osteoarthritis progression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239365

In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy

12 July 2018

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Cytokines and inflammation in cartilage degradation.

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239365

Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association

12 July 2018

1 reference

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Inhibition of adenosine kinase attenuates interleukin-1- and lipopolysaccharide-induced alterations in articular cartilage metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239365

Regulation of nitric oxide production in osteoarthritic and rheumatoid cartilage. Role of endogenous IL-1 inhibitors

25 September 2018

1 reference

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Nondestructive imaging of human cartilage glycosaminoglycan concentration by MRI.

25 September 2018

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Chondroprotective effect of intraarticular injections of interleukin-1 receptor antagonist in experimental osteoarthritis. Suppression of collagenase-1 expression

25 September 2018

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12 December 2020

Cartilage protection by nitric oxide synthase inhibitors after intraarticular injection of interleukin-1beta in rats

1 reference

12 December 2020

Safety study of intraarticular injection of interleukin 1 receptor antagonist in patients with painful knee osteoarthritis: a multicenter study

1 reference

12 December 2020

A high interleukin 1 receptor antagonist/IL-1beta ratio occurs naturally in knee osteoarthritis

1 reference

12 December 2020

Intraarticular injection of anakinra in osteoarthritis of the knee: a multicenter, randomized, double-blind, placebo-controlled study

1 reference

12 December 2020

Identifiers

DOI

10.1186/AR3430

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Dimensions Publication ID

9 August 2017

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9 August 2017

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