(Q35620087)

9 August 2017

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title

T-cell development made simple (English)

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9 August 2017

Juan Carlos Zúñiga-Pflücker

series ordinal

1

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9 August 2017

1 January 2004

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Nature Reviews Immunology

9 August 2017

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9 August 2017

4

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9 August 2017

1

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9 August 2017

67-72

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The discovery of thymus function and of thymus-derived lymphocytes

9 August 2017

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Lymphostromal interactions in thymic development and function

31 March 2020

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Role of thymic organ structure and stromal composition in steady-state postnatal T-cell production

31 March 2020

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IMMUNOLOGICAL FUNCTION OF THE THYMUS

31 March 2020

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Identification of clonogenic common lymphoid progenitors in mouse bone marrow

31 March 2020

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Thymopoiesis independent of common lymphoid progenitors

31 March 2020

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Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow

31 March 2020

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A developing picture of lymphopoiesis in bone marrow

31 March 2020

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Aspects of early lymphoid commitment

31 March 2020

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Cellular interactions in thymocyte development.

31 March 2020

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A positive look at double-negative thymocytes

31 March 2020

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Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development

31 March 2020

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Stromal cells provide the matrix for migration of early lymphoid progenitors through the thymic cortex

31 March 2020

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Kinetics of steady-state differentiation and mapping of intrathymic-signaling environments by stem cell transplantation in nonirradiated mice

31 March 2020

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Role of chemokines in thymocyte development

31 March 2020

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MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus

31 March 2020

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Development of cytolytic T lymphocyte precursors in organ-cultured mouse embryonic thymus rudiments

31 March 2020

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Effect of deoxyguanosine on lymphopoiesis in the developing thymus rudimentin vitro: Application in the production of chimeric thymus rudiments

31 March 2020

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Fetal thymic organ cultures

31 March 2020

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Conditions controlling the proliferation of haemopoietic stem cells in vitro

31 March 2020

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Colony formation in agar by adult bone marrow multipotential hemopoietic cells

31 March 2020

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The influence of S17 stromal cells and interleukin 7 on B cell development

31 March 2020

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A stromal cell-derived membrane protein that supports hematopoietic stem cells

31 March 2020

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Generation of lymphohematopoietic cells from embryonic stem cells in culture

31 March 2020

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In vitro development of primitive and definitive erythrocytes from different precursors

31 March 2020

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Lymphohematopoietic development from embryonic stem cells in vitro

31 March 2020

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Expression and function of CD105 during the onset of hematopoiesis from Flk1(+) precursors.

31 March 2020

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Functional characterization of B lymphocytes generated in vitro from embryonic stem cells.

31 March 2020

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Identification of a novel developmental stage marking lineage commitment of progenitor thymocytes

31 March 2020

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Notch signaling in lymphopoiesis.

31 March 2020

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Deficient T cell fate specification in mice with an induced inactivation of Notch1.

31 March 2020

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Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

31 March 2020

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Notch activity influences the alphabeta versus gammadelta T cell lineage decision

31 March 2020

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Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.

31 March 2020

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A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development

31 March 2020

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Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength

31 March 2020

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An activated form of Notch influences the choice between CD4 and CD8 T cell lineages

31 March 2020

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Notch signaling in T cell development

31 March 2020

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Active form of Notch imposes T cell fate in human progenitor cells

31 March 2020

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Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision

31 March 2020

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Active Form of Notch Members Can Enforce T Lymphopoiesis on Lymphoid Progenitors in the Monolayer Culture Specific for B Cell Development

31 March 2020

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Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation

31 March 2020

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Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus.

31 March 2020

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Notch ligand-bearing thymic epithelial cells initiate and sustain Notch signaling in thymocytes independently of T cell receptor signaling

31 March 2020

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Entry into the thymic microenvironment triggers Notch activation in the earliest migrant T cell progenitors.

31 March 2020

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Microenvironmental regulation of Notch signalling in T cell development.

31 March 2020

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Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

31 March 2020

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A role for pref-1 and HES-1 in thymocyte development.

31 March 2020

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Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro.

31 March 2020

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T cell development in culture

31 March 2020

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Fine-tuning Notch1 activation by endocytosis and glycosylation

31 March 2020

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Speculation on the lineage relationships among CD4(-)8(+) gut-derived T cells and their role(s).

31 March 2020

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Major T cell progenitor activity in bone marrow-derived spleen colonies

31 March 2020

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An alternate pathway for T cell development supported by the bone marrow microenvironment: recapitulation of thymic maturation

31 March 2020

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Cutting edge: an essential role for Notch-1 in the development of both thymus-independent and -dependent T cells in the gut.

31 March 2020

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A single micromanipulated stem cell gives rise to multiple T-cell receptor gene rearrangements in the thymus in vitro

31 March 2020

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Clonal Characterization of a Bipotent T Cell and NK Cell Progenitor in the Mouse Fetal Thymus

31 March 2020

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Commitment of common T/Natural killer (NK) progenitors to unipotent T and NK progenitors in the murine fetal thymus revealed by a single progenitor assay

31 March 2020

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Gene silencing in mammals by small interfering RNAs

31 March 2020

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Projection of an immunological self shadow within the thymus by the aire protein

31 March 2020

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Surface expression of Notch1 on thymocytes: correlation with the double-negative to double-positive transition

31 March 2020

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Notch signaling: cell fate control and signal integration in development

31 March 2020

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Notch receptor cleavage depends on but is not directly executed by presenilins

31 March 2020

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MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

31 March 2020

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A histone deacetylase corepressor complex regulates the Notch signal transduction pathway

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI1257

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9 August 2017

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PubMed ID

14704769