(Q52117223)

22 April 2018

title

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes (English)

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22 April 2018

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5

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22 April 2018

author name string

Anita Wolfer

1

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22 April 2018

Anne Wilson

2

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22 April 2018

Mohamed Nemir

3

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22 April 2018

H Robson MacDonald

4

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22 April 2018

language of work or name

English

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publication date

1 June 2002

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22 April 2018

published in

Immunity

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22 April 2018

volume

16

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22 April 2018

issue

6

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22 April 2018

page(s)

869-879

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22 April 2018

Early T cell receptor beta gene expression is regulated by the pre-T cell receptor-CD3 complex

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Early thymocyte development is regulated by modulation of E2A protein activity

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Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength

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Helix-loop-helix proteins regulate pre-TCR and TCR signaling through modulation of Rel/NF-kappaB activities

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Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

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Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

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RAG-1-deficient mice have no mature B and T lymphocytes

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FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor

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Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments

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Notch1 expression in early lymphopoiesis influences B versus T lineage determination

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Deficient T cell fate specification in mice with an induced inactivation of Notch1.

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An activated form of Notch influences the choice between CD4 and CD8 T cell lineages

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7 January 2021

Molecular and cellular events in early thymocyte development

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7 January 2021

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7 January 2021

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7 January 2021

Limited effect of chromatin remodeling on D(beta)-to-J(beta) recombination in CD4+CD8+ thymocyte: implications for a new aspect in the regulation of TCR beta gene recombination.

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7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

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7 January 2021

Activated Ras signals differentiation and expansion of CD4+8+ thymocytes

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7 January 2021

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7 January 2021

Notch activity influences the alphabeta versus gammadelta T cell lineage decision

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7 January 2021

Unexpectedly late expression of intracellular CD3epsilon and TCR gammadelta proteins during adult thymus development

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7 January 2021

Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus.

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7 January 2021

Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development

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7 January 2021

A novel Notch ligand, Dll4, induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer

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7 January 2021

The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate

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7 January 2021

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Identifiers

DOI

1 reference

22 April 2018

1 reference

22 April 2018