(Q35621018)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Distinct intracellular motifs of Delta mediate its ubiquitylation and activation by Mindbomb1 and Neuralized (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

main subject

Mind bomb 1 Dmel_CG5841

1 reference

GOA release 2020-03-11

Neuralized Dmel_CG11988

1 reference

GOA release 2020-03-11

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Christos Delidakis

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Aikaterini Daskalaki

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Nevine A Shalaby

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Kristina Kux

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Giorgos Tsoumpekos

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Marc A T Muskavitch

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

language of work or name

English

0 references

publication date

1 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

published in

Journal of Cell Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

195

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

1017-1031

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

Semi-automated Acanthamoeba polyphaga detection and computation of Salmonella typhimurium concentration in spatio-temporal images

18 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Notch ligand ubiquitylation: what is it good for?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

The functions of auxilin and Rab11 in Drosophila suggest that the fundamental role of ligand endocytosis in notch signaling cells is not recycling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Ubiquitin: same molecule, different degradation pathways

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Cis-interactions between Notch and Delta generate mutually exclusive signalling states

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Neuralized promotes basal to apical transcytosis of delta in epithelial cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

cis-Inhibition of Notch by endogenous Delta biases the outcome of lateral inhibition.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Both inhibition and activation of Notch signaling rely on a conserved Neuralized-binding motif in Bearded proteins and the Notch ligand Delta

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

RING domain E3 ubiquitin ligases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

The canonical Notch signaling pathway: unfolding the activation mechanism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Ubiquitin in trafficking: the network at work

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

The molecular logic of Notch signaling--a structural and biochemical perspective.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

The intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

The clathrin-binding motif and the J-domain of Drosophila Auxilin are essential for facilitating Notch ligand endocytosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Auxilin is essential for Delta signaling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

An obligatory role of mind bomb-1 in notch signaling of mammalian development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Nemo: a computational tool for analyzing nematode locomotion

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Regulation of Notch signalling by endocytosis and endosomal sorting

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Mind bomb 1 is essential for generating functional Notch ligands to activate Notch

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Mind bomb-2 is an E3 ligase for Notch ligand

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Hrs mediates downregulation of multiple signalling receptors in Drosophila

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Notch-induced proteolysis and nuclear localization of the Delta ligand

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Xenopus neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates Notch signaling.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Senseless, a Zn finger transcription factor, is necessary and sufficient for sensory organ development in Drosophila

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Ligand endocytosis drives receptor dissociation and activation in the Notch pathway

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Notch signalling in Drosophila: three ways to use a pathway

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Requirement for dynamin during Notch signaling in Drosophila neurogenesis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Dorsal-ventral signaling in limb development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

A dominant-negative form of Serrate acts as a general antagonist of Notch activation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

A hierarchy of cross-regulation involving Notch, wingless, vestigial and cut organizes the dorsal/ventral axis of the Drosophila wing.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Bombyx EcR (BmEcR) and Bombyx USP (BmCF1) combine to form a functional ecdysone receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

The emergence of sense organs in the wing disc of Drosophila.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Bearded family members inhibit Neuralized-mediated endocytosis and signaling activity of Delta in Drosophila.

12 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Sara endosomes and the maintenance of Dpp signaling levels across mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Antagonistic interactions between wingless and decapentaplegic responsible for dorsal-ventral pattern in the Drosophila Leg.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Lateral inhibition in proneural clusters: cis-regulatory logic and default repression by Suppressor of Hairless

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Three modules of zebrafish Mind bomb work cooperatively to promote Delta ubiquitination and endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Endocytosis-independent mechanisms of Delta ligand proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Dorsal-ventral pattern of Delta trafficking is established by a Snail-Tom-Neuralized pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

An intrinsic dominant negative activity of serrate that is modulated during wing development in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Unequal segregation of Neuralized biases Notch activation during asymmetric cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

neuralized Encodes a peripheral membrane protein involved in delta signaling and endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

The interplay between DSL proteins and ubiquitin ligases in Notch signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Neuralized contains a phosphoinositide-binding motif required downstream of ubiquitination for delta endocytosis and notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Neuralized functions as an E3 ubiquitin ligase during Drosophila development

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

The characterization of zebrafish antimorphic mib alleles reveals that Mib and Mind bomb-2 (Mib2) function redundantly

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201105166

Rab11 polarization of the Drosophila oocyte: a novel link between membrane trafficking, microtubule organization, and oskar mRNA localization and translation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Feedback regulation is central to Delta-Notch signalling required for Drosophila wing vein morphogenesis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

The function and regulation of cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

A dual function of phyllopod in Drosophila external sensory organ development: cell fate specification of sensory organ precursor and its progeny.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241720

15 November 2018

Identifiers

DOI

10.1083/JCB.201105166

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162135%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

22162135

1 reference