(Q35623322)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17257395%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

The role of pneumolysin in mediating lung damage in a lethal pneumococcal pneumonia murine model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17257395%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

pneumococcal pneumonia

1 reference

1 reference

María Del Mar García Suárez

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17257395%20AND%20SRC:MED&resulttype=core&format=json

Aurora Astudillo-González

24 December 2019

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17257395%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

7

Liise-Anne Pirofski

1 reference

24 December 2019

Noelia Flórez

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17257395%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Fernando Vázquez

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17257395%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Roberto Villaverde

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17257395%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Kevin Fabrizio

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17257395%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Francisco J Méndez

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17257395%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

language of work or name

1 reference

26 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17257395%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17257395%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17257395%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

page(s)

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17257395%20AND%20SRC:MED&resulttype=core&format=json

Streptococcus pneumoniae: the role of apoptosis in host defense and pathogenesis.

24 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Construction and immunological characterization of a novel nontoxic protective pneumolysin mutant for use in future pneumococcal vaccines

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

The apoptotic response to pneumolysin is Toll-like receptor 4 dependent and protects against pneumococcal disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Bacterial programmed cell death of cerebral endothelial cells involves dual death pathways

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

The role of pneumolysin in pneumococcal pneumonia and meningitis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Inhibition of MAPK signaling pathways by VopA from Vibrio parahaemolyticus

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Streptococcus pneumoniae-induced caspase 6-dependent apoptosis in lung epithelium

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Protection against pneumococcal pneumonia in mice by monoclonal antibodies to pneumolysin.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Pneumolysin-induced lung injury is independent of leukocyte trafficking into the alveolar space

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Role of Toll-like receptor 4 in gram-positive and gram-negative pneumonia in mice.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Bacterial pathogens modulate an apoptosis differentiation program in human neutrophils

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Reduced release of pneumolysin by Streptococcus pneumoniae in vitro and in vivo after treatment with nonbacteriolytic antibiotics in comparison to ceftriaxone

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Pneumococcal behavior and host responses during bronchopneumonia are affected differently by the cytolytic and complement-activating activities of pneumolysin.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Sensitivities of human monocytes and epithelial cells to pneumolysin are different.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

The family of thiol-activated, cholesterol-binding cytolysins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Protection against Streptococcus pneumoniae elicited by immunization with pneumolysin and CbpA.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

The autolytic enzyme LytA of Streptococcus pneumoniae is not responsible for releasing pneumolysin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Pneumolysin potentiates production of prostaglandin E(2) and leukotriene B(4) by human neutrophils

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Pneumolysin is the main inducer of cytotoxicity to brain microvascular endothelial cells caused by Streptococcus pneumoniae

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Host cellular immune response to pneumococcal lung infection in mice.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

The induction of apoptosis by bacterial pathogens

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

The molecular mechanism of pneumolysin, a virulence factor from Streptococcus pneumoniae.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Pneumococcal trafficking across the blood-brain barrier. Molecular analysis of a novel bidirectional pathway

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Toxicity of pneumolysin to pulmonary alveolar epithelial cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Pneumolysin activates phospholipase A in pulmonary artery endothelial cells.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Immunization of mice with pneumolysin toxoid confers a significant degree of protection against at least nine serotypes of Streptococcus pneumoniae

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Activation of human complement by the pneumococcal toxin pneumolysin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Toxicity of pneumolysin to pulmonary endothelial cells in vitro

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Roles of interleukin-6 and macrophage inflammatory protein-2 in pneumolysin-induced lung inflammation in mice

27 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-8-3

Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-8-3

Two distinct mechanisms for induction of dendritic cell apoptosis in response to intact Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-8-3

Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-8-3

Neurotoxicity of pneumolysin, a major pneumococcal virulence factor, involves calcium influx and depends on activation of p38 mitogen-activated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-8-3

Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-8-3

Role of pneumolysin for the development of acute lung injury in pneumococcal pneumonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-8-3

Streptococcus pneumoniae-associated human macrophage apoptosis after bacterial internalization via complement and Fcgamma receptors correlates with intracellular bacterial load.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-8-3

Alveolar Macrophage Apoptosis Contributes to Pneumococcal Clearance in a Resolving Model of Pulmonary Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-8-3

Fas-mediated acute lung injury requires fas expression on nonmyeloid cells of the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-8-3

Pneumolysin as a vaccine and drug target in the prevention and treatment of invasive pneumococcal disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

Nitric oxide levels regulate macrophage commitment to apoptosis or necrosis during pneumococcal infection.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1790890

The effect of the pneumococcal toxin, pneumolysin on brain ependymal cilia

25 September 2018

1 reference

12 December 2020

Induction of necrosis and apoptosis of neutrophil granulocytes by Streptococcus pneumoniae

1 reference

12 December 2020

A specific and ultrasensitive chemiluminescent sandwich ELISA test for the detection and quantitation of pneumolysin

1 reference

12 December 2020

Dual Phases of Apoptosis in Pneumococcal Meningitis

1 reference

12 December 2020

Comparative efficacy of autolysin and pneumolysin as immunogens protecting mice against infection by Streptococcus pneumoniae

1 reference

12 December 2020

The role of pneumolysin and autolysin in the pathology of pneumonia and septicemia in mice infected with a type 2 pneumococcus

1 reference

12 December 2020

Identifiers

DOI

10.1186/1465-9921-8-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17257395%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

24 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17257395%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

PubMed publication ID

17257395

1 reference