(Q35623435)

English

Selective therapeutic targeting of the anaplastic lymphoma kinase with liposomal siRNA induces apoptosis and inhibits angiogenesis in neuroblastoma

scientific article published on 9 August 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Selective therapeutic targeting of the anaplastic lymphoma kinase with liposomal siRNA induces apoptosis and inhibits angiogenesis in neuroblastoma (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

1 reference

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inferred from title

Roberto Chiarle

13

object named as

Roberto Chiarle

0 references

Cinzia Martinengo

5

object named as

Cinzia Martinengo

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Chiara Ambrogio

2

object named as

Chiara Ambrogio

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Daniela Di Paolo

object named as

Daniela Di Paolo

1

0 references

Fabio Pastorino

object named as

Fabio Pastorino

3

0 references

object named as

Patrizia Perri

15

0 references

Gabriella Pagnan

object named as

Gabriella Pagnan

8

0 references

object named as

Mirco Ponzoni

14

0 references

Domenico Ribatti

11

object named as

Domenico Ribatti

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

author name string

Chiara Brignole

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Roberta Carosio

6

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Monica Loi

7

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Laura Emionite

9

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Michele Cilli

10

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Theresa M Allen

12

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

publication date

9 August 2011

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Molecular Therapy

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

19

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

2201-2212

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Neuroblastoma-targeted nanoparticles entrapping siRNA specifically knockdown ALK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

The constitutive activity of the ALK mutated at positions F1174 or R1275 impairs receptor trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Appearance of the novel activating F1174S ALK mutation in neuroblastoma correlates with aggressive tumor progression and unresponsiveness to therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

The neuroblastoma-associated F1174L ALK mutation causes resistance to an ALK kinase inhibitor in ALK-translocated cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor.

1 reference

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12 July 2018

Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Tumor regression and curability of preclinical neuroblastoma models by PEGylated SN38 (EZN-2208), a novel topoisomerase I inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Sustained small interfering RNA delivery by mesoporous silicon particles

1 reference

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12 July 2018

The dicey role of Dicer: implications for RNAi therapy

1 reference

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12 July 2018

NPM-ALK oncogenic tyrosine kinase controls T-cell identity by transcriptional regulation and epigenetic silencing in lymphoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Inhibition of ALK signaling for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Mutation-independent anaplastic lymphoma kinase overexpression in poor prognosis neuroblastoma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Drug delivery-mediated control of RNA immunostimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Anaplastic lymphoma kinase: signalling in development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Anaplastic lymphoma kinase: role in cancer pathogenesis and small-molecule inhibitor development for therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Knocking down barriers: advances in siRNA delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Enhanced antitumor efficacy of clinical-grade vasculature-targeted liposomal doxorubicin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

PHOX2A and PHOX2B genes are highly co-expressed in human neuroblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Activating mutations in ALK provide a therapeutic target in neuroblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Oncogenic mutations of ALK kinase in neuroblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Identification of ALK as a major familial neuroblastoma predisposition gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Angiogenesis as a target in neuroblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

The anaplastic lymphoma kinase in the pathogenesis of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Targeting liposomal chemotherapy via both tumor cell-specific and tumor vasculature-specific ligands potentiates therapeutic efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Effect of bortezomib on human neuroblastoma cell growth, apoptosis, and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Antiangiogenic strategies in neuroblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Immune cell-mediated antitumor activities of GD2-targeted liposomal c-myb antisense oligonucleotides containing CpG motifs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Targeted liposomal c-myc antisense oligodeoxynucleotides induce apoptosis and inhibit tumor growth and metastases in human melanoma models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Anti-GD2 monoclonal antibody immunotherapy: a promising strategy in the prevention of neuroblastoma relapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Neuroblastoma: biological insights into a clinical enigma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Dissemination and growth of cancer cells in metastatic sites

1 reference

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12 July 2018

Targeted delivery of antisense oligonucleotides in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Delivery of c-myb antisense oligodeoxynucleotides to human neuroblastoma cells via disialoganglioside GD(2)-targeted immunoliposomes: antitumor effects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Disialoganglioside GD2 on human neuroblastoma cells: target antigen for monoclonal antibody-mediated cytolysis and suppression of tumor growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242652

12 July 2018

Oncogenic kinase NPM/ALK induces expression of HIF1α mRNA.

1 reference

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25 September 2018

Therapeutic targeting of neuropilin-2 on colorectal carcinoma cells implanted in the murine liver

1 reference

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25 September 2018

Genetic Predisposition to Familial Neuroblastoma: Identification of Two Novel Genomic Regions at 2p and 12p

1 reference

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15 November 2018

Doxorubicin-loaded Fab' fragments of anti-disialoganglioside immunoliposomes selectively inhibit the growth and dissemination of human neuroblastoma in nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21829174

12 December 2020

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Vascular damage and anti-angiogenic effects of tumor vessel-targeted liposomal chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21829174

12 December 2020

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inferred from PubMed ID database lookup

Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft

1 reference

https://pubmed.ncbi.nlm.nih.gov/21829174

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based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/21829174

12 December 2020

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inferred from PubMed ID database lookup

High incidence of DNA mutations and gene amplifications of theALKgene in advanced sporadic neuroblastoma tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/21829174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/MT.2011.142

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

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