(Q35623459)

9 August 2017

title

Phase Ia clinical evaluation of the Plasmodium falciparum blood-stage antigen MSP1 in ChAd63 and MVA vaccine vectors (English)

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9 August 2017

main subject

Plasmodium falciparum

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20

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9 August 2017

6

Alexandra J Spencer

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9 August 2017

Katharine A Collins

4

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Fenella D Halstead

Fenella D Halstead

8

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Katie J. Ewer

Katie J Ewer

5

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Andrew R Williams

Andrew R Williams

7

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Simon J. Draper

Simon J Draper

23

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Adrian V. S. Hill

22

Adrian V S Hill

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9 August 2017

10

Kazutoyo Miura

1 reference

9 August 2017

17

Carole A Long

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9 August 2017

14

Alison M Lawrie

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9 August 2017

15

Eleanor Berrie

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9 August 2017

1

Susanne H Sheehy

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9 August 2017

3

Sean C Elias

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9 August 2017

13

Ian D Poulton

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9 August 2017

18

Stefano Colloca

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9 August 2017

21

Alfredo Nicosia

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9 August 2017

9

Samuel E Moretz

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9 August 2017

author name string

Christopher J A Duncan

2

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9 August 2017

Christian Epp

11

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9 August 2017

Matthew D J Dicks

12

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9 August 2017

Sarah Moyle

16

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9 August 2017

Riccardo Cortese

19

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9 August 2017

language of work or name

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23 August 2011

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9 August 2017

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9 August 2017

volume

19

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9 August 2017

issue

12

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9 August 2017

page(s)

2269-2276

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Transgene optimization, immunogenicity and in vitro efficacy of viral vectored vaccines expressing two alleles of Plasmodium falciparum AMA1

9 August 2017

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1 reference

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27 July 2018

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Tailoring subunit vaccine immunogenicity: maximizing antibody and T cell responses by using combinations of adenovirus, poxvirus and protein-adjuvant vaccines against Plasmodium falciparum MSP1.

27 July 2018

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New candidate vaccines against blood-stage Plasmodium falciparum malaria: prime-boost immunization regimens incorporating human and simian adenoviral vectors and poxviral vectors expressing an optimized antigen based on merozoite surface protein 1

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Growth-inhibitory antibodies are not necessary for protective immunity to malaria infection

27 July 2018

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27 July 2018

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Protection against a malaria challenge by sporozoite inoculation

27 July 2018

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The carboxy-terminus of merozoite surface protein 1: structure, specific antibodies and immunity to malaria.

27 July 2018

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Anti-apical-membrane-antigen-1 antibody is more effective than anti-42-kilodalton-merozoite-surface-protein-1 antibody in inhibiting plasmodium falciparum growth, as determined by the in vitro growth inhibition assay

27 July 2018

1 reference

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Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A.

27 July 2018

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Recombinant viral vaccines expressing merozoite surface protein-1 induce antibody- and T cell-mediated multistage protection against malaria

27 July 2018

1 reference

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Vaccination with live Plasmodium yoelii blood stage parasites under chloroquine cover induces cross-stage immunity against malaria liver stage

27 July 2018

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HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis

27 July 2018

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Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

27 July 2018

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Single-dose protection against Plasmodium berghei by a simian adenovirus vector using a human cytomegalovirus promoter containing intron A

27 July 2018

1 reference

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Apical membrane antigen 1: a malaria vaccine candidate in review

27 July 2018

1 reference

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Development and characterization of a standardized ELISA including a reference serum on each plate to detect antibodies induced by experimental malaria vaccines

27 July 2018

1 reference

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Protection of rhesus monkeys by a DNA prime/poxvirus boost malaria vaccine depends on optimal DNA priming and inclusion of blood stage antigens

27 July 2018

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The importance of human FcgammaRI in mediating protection to malaria

27 July 2018

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Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector

27 July 2018

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27 July 2018

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27 July 2018

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Merozoite surface protein 1-specific immune response is protective against exoerythrocytic forms of Plasmodium yoelii

27 July 2018

1 reference

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Immunity to malaria after administration of ultra-low doses of red cells infected with Plasmodium falciparum

27 July 2018

1 reference

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Identification of T cell epitopes on the 33-kDa fragment of Plasmodium yoelii merozoite surface protein 1 and their antibody-independent protective role in immunity to blood stage malaria

27 July 2018

1 reference

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Protective immune responses to the 42-kilodalton (kDa) region of Plasmodium yoelii merozoite surface protein 1 are induced by the C-terminal 19-kDa region but not by the adjacent 33-kDa region

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

Processing of the precursor to the major merozoite surface antigens of Plasmodium falciparum.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

Primary structure of the precursor to the three major surface antigens of Plasmodium falciparum merozoites

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

Defying malaria: Arming T cells to halt malaria

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

Enhancing blood-stage malaria subunit vaccine immunogenicity in rhesus macaques by combining adenovirus, poxvirus, and protein-in-adjuvant vaccines

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

Blood-stage malaria vaccines - recent progress and future challenges

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

Involvement of CD8+ T cells in protective immunity against murine blood-stage infection with Plasmodium yoelii 17XL strain

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

Prime-boost vectored malaria vaccines: progress and prospects

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

Prevalence of serum neutralizing antibodies against chimpanzee adenovirus 63 and human adenovirus 5 in Kenyan children, in the context of vaccine vector efficacy

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in Western Kenya

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys

25 September 2018

1 reference

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Effective induction of high-titer antibodies by viral vector vaccines

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

Ex vivo cytokine and memory T cell responses to the 42-kDa fragment of Plasmodium falciparum merozoite surface protein-1 in vaccinated volunteers

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

Antigenicity and immunogenicity of the N-terminal 33-kDa processing fragment of the Plasmodium falciparum merozoite surface protein 1, MSP1: implications for vaccine development

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

Identification of frequently recognized dimorphic T-cell epitopes in plasmodium falciparum merozoite surface protein-1 in West and East Africans: lack of correlation of immune recognition and allelic prevalence

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

CD4+ T cells acting independently of antibody contribute to protective immunity to Plasmodium chabaudi infection after apical membrane antigen 1 immunization

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242658

25 September 2018

Identifiers

DOI

10.1038/MT.2011.176

1 reference

9 August 2017

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9 August 2017

1 reference