(Q35624029)

9 August 2017

title

Characterization of the basic charge variants of a human IgG1: effect of copper concentration in cell culture media (English)

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9 August 2017

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Timothy Kaschak

1

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9 August 2017

Daniel Boyd

2

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9 August 2017

Franklin Lu

3

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9 August 2017

Gayle Derfus

4

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9 August 2017

Brian Kluck

5

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9 August 2017

Bartek Nogal

6

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9 August 2017

Craig Emery

7

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9 August 2017

Christie Summers

8

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9 August 2017

Kai Zheng

9

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9 August 2017

Robert Bayer

10

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9 August 2017

Ashraf Amanullah

11

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9 August 2017

Boxu Yan

12

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9 August 2017

publication date

1 November 2011

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9 August 2017

published in

Monoclonal Antibodies

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9 August 2017

volume

3

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9 August 2017

issue

6

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9 August 2017

page(s)

577-583

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Cell culture and gene transcription effects of copper sulfate on Chinese hamster ovary cells

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

Charge variants in IgG1: Isolation, characterization, in vitro binding properties and pharmacokinetics in rats

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

Heterogeneity of monoclonal antibodies revealed by charge-sensitive methods

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

Monoclonal antibodies--regulatory challenges

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

Analysis of post-translational modifications in recombinant monoclonal antibody IgG1 by reversed-phase liquid chromatography/mass spectrometry.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

Trafficking of a secretory granule membrane protein is sensitive to copper

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

Post-translational modifications in the context of therapeutic proteins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

The copper-enzyme family of dopamine beta-monooxygenase and peptidylglycine alpha-hydroxylating monooxygenase: resolving the chemical pathway for substrate hydroxylation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

The catalytic copper of peptidylglycine alpha-hydroxylating monooxygenase also plays a critical structural role

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

Effect of copper sulfate on performance of a serum-free CHO cell culture process and the level of free thiol in the recombinant antibody expressed

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

Characterizing biological products and assessing comparability following manufacturing changes.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

Expression and characterization of human bifunctional peptidylglycine alpha-amidating monooxygenase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

New insights into copper monooxygenases and peptide amidation: structure, mechanism and function

12 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

12 July 2018

https://api.crossref.org/works/10.4161%2FMABS.3.6.17959

Effect of C2-associated carbohydrate structure on Ig effector function: studies with chimeric mouse-human IgG1 antibodies in glycosylation mutants of Chinese hamster ovary cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

Processing of C-terminal lysine and arginine residues of proteins isolated from mammalian cell culture.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

In vivo deamidation characterization of monoclonal antibody by LC/MS/MS.

12 July 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.3.6.17959

Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.3.6.17959

Formation of pyroglutamic acid from N-terminal glutamic acid in immunoglobulin gamma antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.3.6.17959

Cation exchange-HPLC and mass spectrometry reveal C-terminal amidation of an IgG1 heavy chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.3.6.17959

Multiproduct high-resolution monoclonal antibody charge variant separations by pH gradient ion-exchange chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.3.6.17959

Heterogeneity of recombinant antibodies: linking structure to function

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

Identification of multiple sources of charge heterogeneity in a recombinant antibody.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242844

Characterization of a peptide alpha-amidation activity in human plasma and tissues

25 September 2018

1 reference

12 December 2020

Characterization of peptide alpha-amidation activity in human cerebrospinal fluid and central nervous system tissue

1 reference

12 December 2020

Comparison of methionine oxidation in thermal stability and chemically stressed samples of a fully human monoclonal antibody

1 reference

12 December 2020

Toward biosimilar monoclonal antibodies

1 reference

12 December 2020

Identifiers

DOI

10.4161/MABS.3.6.17959

1 reference

9 August 2017

1 reference

9 August 2017

1 reference