(Q35625401)

25955657

9 August 2017

title

PKM2 Subcellular Localization Is Involved in Oxaliplatin Resistance Acquisition in HT29 Human Colorectal Cancer Cell Lines (English)

1 reference

9 August 2017

1 reference

1 reference

1 reference

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25955657%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Eva Martínez-Balibrea

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25955657%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Alba Ginés

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25955657%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Sara Bystrup

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25955657%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Vicenç Ruiz de Porras

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25955657%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Cristina Guardia

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25955657%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Eva Musulén

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25955657%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

José Luis Manzano

7

1 reference

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11 June 2020

Laura Layos

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25955657%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Albert Abad

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25955657%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

language of work or name

English

0 references

publication date

8 May 2015

1 reference

9 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25955657%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

10

1 reference

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11 June 2020

issue

5

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11 June 2020

page(s)

e0123830

1 reference

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Creative Commons Attribution 4.0 International

11 June 2020

copyright license

start time

8 May 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis

12 July 2018

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12 July 2018

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Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase

12 July 2018

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12 July 2018

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Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

12 July 2018

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Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

12 July 2018

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Chemoresistant colorectal cancer cells and cancer stem cells mediate growth and survival of bystander cells

12 July 2018

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Identification of phosphorylated serine-15 and -82 residues of HSPB1 in 5-fluorouracil-resistant colorectal cancer cells by proteomics

12 July 2018

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The Role of BH3-Only Proteins in Tumor Cell Development, Signaling, and Treatment

12 July 2018

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Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.

12 July 2018

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Evidence for an alternative glycolytic pathway in rapidly proliferating cells

12 July 2018

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Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth

12 July 2018

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12 July 2018

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A proteomic approach links decreased pyruvate kinase M2 expression to oxaliplatin resistance in patients with colorectal cancer and in human cell lines

12 July 2018

1 reference

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Pharmacogenomic approach for the identification of novel determinants of acquired resistance to oxaliplatin in colorectal cancer

12 July 2018

1 reference

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Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway

12 July 2018

1 reference

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425499

Pyruvate kinase M2 is a phosphotyrosine-binding protein

12 July 2018

1 reference

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Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription

12 July 2018

1 reference

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12 July 2018

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p53 dependent and independent sensitivity to oxaliplatin of colon cancer cells

12 July 2018

1 reference

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Regulation of cell proliferation by interleukin-3-induced nuclear translocation of pyruvate kinase.

12 July 2018

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12 July 2018

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Cell cycle arrest by oxaliplatin on cancer cells

12 July 2018

1 reference

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Nuclear translocation of the tumor marker pyruvate kinase M2 induces programmed cell death

12 July 2018

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12 July 2018

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Expression analysis of genes involved in oxaliplatin response and development of oxaliplatin-resistant HT29 colon cancer cells.

12 July 2018

1 reference

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Role of p21waf1/cip1 in effects of oxaliplatin in colorectal cancer cells

12 July 2018

1 reference

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Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells.

12 July 2018

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Decreased pyruvate kinase M2 activity linked to cisplatin resistance in human gastric carcinoma cell lines

12 July 2018

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Cellular determinants of oxaliplatin sensitivity in colon cancer cell lines

12 July 2018

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Genotoxic exposure is associated with alterations in glucose uptake and metabolism.

12 July 2018

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12 July 2018

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12 July 2018

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HDAC8 and STAT3 repress BMF gene activity in colon cancer cells

12 July 2018

1 reference

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Role of autophagy in resistance to oxaliplatin in hepatocellular carcinoma cells

25 September 2018

1 reference

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The role of p53 in glucose metabolism

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425499

The SUMO-E3 ligase PIAS3 targets pyruvate kinase M2.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425499

The E3 ubiquitin ligase cIAP1 binds and ubiquitinates caspase-3 and -7 via unique mechanisms at distinct steps in their processing

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425499

25 September 2018

1 reference

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Inhibition of G1/S transition potentiates oxaliplatin-induced cell death in colon cancer cell lines

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25955657

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/25955657

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0123830

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25955657%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25955657%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

25955657

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25955657%20AND%20SRC:MED&resulttype=core&format=json