(Q35627697)

9 August 2017

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title

Anti-interleukin-5 monoclonal antibodies: preclinical and clinical evidence in asthma models (English)

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9 August 2017

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Maggie J Leckie

1

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9 August 2017

publication date

1 January 2003

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Treatments in Respiratory Medicine

9 August 2017

published in

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9 August 2017

volume

2

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9 August 2017

issue

3

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9 August 2017

page(s)

245-259

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Eosinophils and neutrophils

9 August 2017

cites work

1 reference

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21 January 2018

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Airway wall remodelling in asthma

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Cytokine regulation of eosinophil function

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Effect of anti-IL-5 and IL-5 on airway hyperreactivity and eosinophils in guinea pigs

21 January 2018

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Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model

21 January 2018

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Development of IL-5 receptor antagonists

21 January 2018

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Ovalbumin sensitization changes the inflammatory response to subsequent parainfluenza infection. Eosinophils mediate airway hyperresponsiveness, m(2) muscarinic receptor dysfunction, and antiviral effects

21 January 2018

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The late, but not early, asthmatic response is dependent on IL-5 and correlates with eosinophil infiltration

21 January 2018

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Anti-IL-5 monoclonal antibody inhibits allergic late phase bronchial eosinophilia in guinea pigs: a therapeutic approach

21 January 2018

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Antibody against interleukin-5 prevents antigen-induced eosinophil infiltration and bronchial hyperreactivity in the guinea pig airways

21 January 2018

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Inhibitory effect of the TRFK-5 anti-IL-5 antibody in a guinea pig model of asthma

21 January 2018

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Antibody to interleukin-5 inhibits virus-induced airway hyperresponsiveness to histamine in guinea pigs

21 January 2018

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Pulmonary biology of anti-interleukin 5 antibodies

21 January 2018

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Effect of dexamethasone and cyclosporin A on allergen-induced airway hyperresponsiveness and inflammatory cell responses in sensitized Brown-Norway rats

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21 January 2018

Late asthmatic responses

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Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.

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Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway.

21 January 2018

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The trials and tribulations of IL-5, eosinophils, and allergic asthma

21 January 2018

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Human eosinophil major basic protein induces airway constriction and airway hyperresponsiveness in primates

21 January 2018

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Reducing IgE levels as a strategy for the treatment of asthma

21 January 2018

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Late asthmatic reactions provoked by intradermal injection of T-cell peptide epitopes are not associated with bronchial mucosal infiltration of eosinophils or T(H)2-type cells or with elevated concentrations of histamine or eicosanoids in bronchoalv

21 January 2018

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21 January 2018

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Peripheral blood CD4 but not CD8 t-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: effect of glucocorticoid therapy

21 January 2018

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21 January 2018

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Signaling through the beta2 integrin prolongs eosinophil survival.

21 January 2018

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Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation

21 January 2018

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CCR3 blockade as a new therapy for asthma

21 January 2018

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Treatment of allergic asthma with monoclonal anti-IgE antibody. rhuMAb-E25 Study Group.

21 January 2018

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Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Randomised, dose-ranging, placebo-controlled study of chimeric antibody to CD4 (keliximab) in chronic severe asthma

21 January 2018

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Anti-T cell strategies in asthma

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03256653

Effect of cyclosporin A on the allergen-induced late asthmatic reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256653

Role of the cyclosporin-sensitive transcription factor NFAT1 in the allergic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256653

Assessment of antibodies to double-stranded DNA induced in rheumatoid arthritis patients following treatment with infliximab, a monoclonal antibody to tumor necrosis factor alpha: findings in open-label and randomized placebo-controlled trials

21 January 2018

1 reference

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The effects of an anti-CD4 monoclonal antibody, keliximab, on peripheral blood CD4+ T-cells in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256653

21 January 2018

Identifiers

DOI

10.1007/BF03256653

1 reference

release_ptbuzu2nujenhmpsauf4nkx2sq

9 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ptbuzu2nujenhmpsauf4nkx2sq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference