(Q53536137)

15 May 2018

title

Interleukin-4 receptor in moderate atopic asthma. A phase I/II randomized, placebo-controlled trial. (English)

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15 May 2018

main subject

phase I clinical trial

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phase II clinical trial

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1

L C Borish

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15 May 2018

H S Nelson

2

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15 May 2018

M J Lanz

3

1 reference

15 May 2018

L Claussen

4

1 reference

15 May 2018

J B Whitmore

5

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15 May 2018

J M Agosti

6

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15 May 2018

L Garrison

7

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15 May 2018

language of work or name

English

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publication date

1 December 1999

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15 May 2018

American Journal of Respiratory and Critical Care Medicine

published in

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15 May 2018

volume

160

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15 May 2018

page(s)

1816-1823

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15 May 2018

issue

6

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15 May 2018

Differential regulation of IgG1 and IgE synthesis by interleukin 4.

cites work

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

Human recombinant interleukin 4 induces Fc epsilon R2/CD23 on normal human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

Osteoporosis induced in mice by overproduction of interleukin 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

Interleukin-13: central mediator of allergic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

Requirement for IL-13 independently of IL-4 in experimental asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

Importance of interleukin-4 and interleukin-12 in allergen-induced airway changes in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

Immune responses of IL-4, IL-5, IL-6 deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

T helper cell type 1 (Th1)- and Th2-like responses are present in mice with gastric candidiasis but protective immunity is associated with Th1 development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

Delayed allograft rejection in mice transgenic for a soluble form of the IL-4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

Differences between IL-4R alpha-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

Interleukin 4 is important in protective immunity to a gastrointestinal nematode infection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FAJRCCM.160.6.9808146

10.1164/AJRCCM.160.6.9808146

21 January 2018

Identifiers

DOI

1 reference

15 May 2018

PubMed ID

10588591

1 reference

15 May 2018