(Q35639911)

9 August 2017

title

The membrane-proximal intracellular domain of the epidermal growth factor receptor underlies negative cooperativity in ligand binding (English)

1 reference

9 August 2017

1 reference

Sangeeta Adak

1

1 reference

9 August 2017

Katherine S Yang

series ordinal

2

1 reference

9 August 2017

Jennifer Macdonald-Obermann

series ordinal

3

1 reference

9 August 2017

Linda J Pike

series ordinal

4

1 reference

9 August 2017

language of work or name

English

0 references

publication date

8 November 2011

1 reference

9 August 2017

number of pages

10

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

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9 August 2017

volume

286

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9 August 2017

issue

52

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9 August 2017

page(s)

45146-45155

1 reference

The tethering arm of the EGF receptor is required for negative cooperativity and signal transduction.

9 August 2017

cites work

1 reference

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12 July 2018

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Cell signaling by receptor tyrosine kinases

12 July 2018

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Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment

12 July 2018

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The Juxtamembrane Region of the EGF Receptor Functions as an Activation Domain

12 July 2018

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Palmitoylation of the EGF receptor impairs signal transduction and abolishes high-affinity ligand binding

12 July 2018

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EGFR family: structure physiology signalling and therapeutic targets

12 July 2018

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All EGF(ErbB) receptors have preformed homo- and heterodimeric structures in living cells.

12 July 2018

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ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling

12 July 2018

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Heterogeneity in EGF-binding affinities arises from negative cooperativity in an aggregating system

12 July 2018

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Epidermal growth factor receptor juxtamembrane region regulates allosteric tyrosine kinase activation

12 July 2018

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The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG1478 increases the formation of inactive untethered EGFR dimers. Implications for combination therapy with monoclonal antibody 806.

12 July 2018

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An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

12 July 2018

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Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis

12 July 2018

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ERBB receptors and cancer: the complexity of targeted inhibitors

12 July 2018

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EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

12 July 2018

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Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

12 July 2018

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Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha

12 July 2018

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Ligand-independent dimer formation of epidermal growth factor receptor (EGFR) is a step separable from ligand-induced EGFR signaling

12 July 2018

1 reference

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Preformed oligomeric epidermal growth factor receptors undergo an ectodomain structure change during signaling

12 July 2018

1 reference

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Single-molecule imaging of EGFR signalling on the surface of living cells

12 July 2018

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The kinase domain and membrane localization determine intracellular interactions between epidermal growth factor receptors

12 July 2018

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Oxidative iodine monochloride iodination technique

12 July 2018

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Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

12 July 2018

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Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248003

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

12 July 2018

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High affinity epidermal growth factor receptors on the surface of A431 cells have restricted lateral diffusion

12 July 2018

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Epidermal growth factor receptor threonine and serine residues phosphorylated in vivo.

12 July 2018

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Epidermal growth factor (EGF) receptor T669 peptide kinase from 3T3-L1 cells is an EGF-stimulated "MAP" kinase

12 July 2018

1 reference

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Unliganded epidermal growth factor receptor dimerization induced by direct interaction of quinazolines with the ATP binding site.

12 July 2018

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The intracellular juxtamembrane domain of the epidermal growth factor (EGF) receptor is responsible for the allosteric regulation of EGF binding

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M111.274175

Linkage of protein assembly to protein-DNA binding.

21 January 2018

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Signaling-inactive epidermal growth factor receptor/ligand complexes in intact carcinoma cells by quinazoline tyrosine kinase inhibitors.

21 January 2018

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Autophosphorylation and protein kinase C phosphorylation of the epidermal growth factor receptor. Effect on tyrosine kinase activity and ligand binding affinity

25 September 2018

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Biologically active phorbol esters specifically alter affinity of epidermal growth factor membrane receptors

15 November 2018

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https://api.crossref.org/works/10.1074%2FJBC.M111.274175

Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane

21 January 2018

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Isolation and characterization of two growth factor-stimulated protein kinases that phosphorylate the epidermal growth factor receptor at threonine 669

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22069315

12 December 2020

inferred from PubMed ID database lookup

Resolution of high and low affinity epidermal growth factor receptors. Inhibition of high affinity component by low temperature, cycloheximide, and phorbol esters

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22069315

12 December 2020

inferred from PubMed ID database lookup

Epidermal growth factor. Ability of tumor promoter to alter its degradation, receptor affinity and receptor number

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22069315

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M111.274175

1 reference

9 August 2017

1 reference

9 August 2017

1 reference