(Q35640998)

9 August 2017

title

HIV-1 fitness cost associated with escape from the VRC01 class of CD4 binding site neutralizing antibodies (English)

1 reference

9 August 2017

1 reference

8

John R Mascola

1 reference

9 August 2017

5

Martha C Nason

1 reference

9 August 2017

1

Rebecca M Lynch

1 reference

9 August 2017

4

Sijy O'Dell

1 reference

9 August 2017

3

Lillian Tran

1 reference

9 August 2017

Patrick Wong

2

1 reference

9 August 2017

Yuxing Li

series ordinal

6

1 reference

9 August 2017

Xueling Wu

series ordinal

7

1 reference

9 August 2017

language of work or name

English

0 references

publication date

28 January 2015

1 reference

9 August 2017

1 reference

9 August 2017

volume

89

1 reference

9 August 2017

issue

8

1 reference

9 August 2017

page(s)

4201-4213

1 reference

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

9 August 2017

cites work

1 reference

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Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies

12 July 2018

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Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers

12 July 2018

1 reference

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Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike

12 July 2018

1 reference

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Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

12 July 2018

1 reference

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Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection

12 July 2018

1 reference

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Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes

12 July 2018

1 reference

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HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

12 July 2018

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Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

12 July 2018

1 reference

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The N276 glycosylation site is required for HIV-1 neutralization by the CD4 binding site specific HJ16 monoclonal antibody

12 July 2018

1 reference

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Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies

12 July 2018

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Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

12 July 2018

1 reference

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Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

12 July 2018

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Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

12 July 2018

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Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies

12 July 2018

1 reference

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Role of transmitted Gag CTL polymorphisms in defining replicative capacity and early HIV-1 pathogenesis

12 July 2018

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Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

12 July 2018

1 reference

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HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

12 July 2018

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A single residue within the V5 region of HIV-1 envelope facilitates viral escape from the broadly neutralizing monoclonal antibody VRC01.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Structural insights into key sites of vulnerability on HIV-1 Env and influenza HA.

12 July 2018

1 reference

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Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies

12 July 2018

1 reference

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Broadly neutralizing antibodies developed by an HIV-positive elite neutralizer exact a replication fitness cost on the contemporaneous virus

12 July 2018

1 reference

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Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

The development of CD4 binding site antibodies during HIV-1 infection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Selection pressure on HIV-1 envelope by broadly neutralizing antibodies to the conserved CD4-binding site

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Molecular mechanisms of HIV entry

12 July 2018

1 reference

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Increasing the potency and breadth of an HIV antibody by using structure-based rational design

12 July 2018

1 reference

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Broad neutralization coverage of HIV by multiple highly potent antibodies

12 July 2018

1 reference

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Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals

12 July 2018

1 reference

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Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

12 July 2018

1 reference

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Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

12 July 2018

1 reference

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Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

12 July 2018

1 reference

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Mechanism of neutralization by the broadly neutralizing HIV-1 monoclonal antibody VRC01.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

The B cell response is redundant and highly focused on V1V2 during early subtype C infection in a Zambian seroconverter

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

A maraviroc-resistant HIV-1 with narrow cross-resistance to other CCR5 antagonists depends on both N-terminal and extracellular loop domains of drug-bound CCR5

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

A quantitative affinity-profiling system that reveals distinct CD4/CCR5 usage patterns among human immunodeficiency virus type 1 and simian immunodeficiency virus strains

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) response

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Autologous neutralizing humoral immunity and evolution of the viral envelope in the course of subtype B human immunodeficiency virus type 1 infection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Evaluating neutralizing antibodies against HIV, SIV, and SHIV in luciferase reporter gene assays

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Broad HIV-1 neutralization mediated by CD4-binding site antibodies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Structural definition of a conserved neutralization epitope on HIV-1 gp120

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

T20-insensitive HIV-1 from naive patients exhibits high viral fitness in a novel dual-color competition assay on primary cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Predominant autoantibody production by early human B cell precursors

12 July 2018

1 reference

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Antibody neutralization and escape by HIV-1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Rapid evolution of the neutralizing antibody response to HIV type 1 infection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

A recombinant virus assay using full-length envelope sequences to detect changes in HIV-1 co-receptor usage

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Rapid development of isolate-specific neutralizing antibodies after primary HIV-1 infection and consequent emergence of virus variants which resist neutralization by autologous sera.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Escherichia coli expression, purification, and biological activity of a truncated soluble CD4.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Homotypic antibody responses to fresh clinical isolates of human immunodeficiency virus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

Yet Another Numbering Scheme for Immunoglobulin Variable Domains: An Automatic Modeling and Analysis Tool

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4442379

7 December 2018

Identifiers

DOI

10.1128/JVI.03608-14

1 reference

release_2brijlpxavhahaoqqqiubrnixe

9 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2brijlpxavhahaoqqqiubrnixe

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4442379

1 reference

9 August 2017

1 reference