(Q35642624)

9 August 2017

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title

Glutathione analogues in cancer treatment (English)

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9 August 2017

David Hamilton

1

1 reference

PubMed ID

14751089

9 August 2017

Gerald Batist

series ordinal

2

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9 August 2017

1 March 2004

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9 August 2017

Current Oncology Reports

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9 August 2017

6

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9 August 2017

116-122

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9 August 2017

2

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https://scigraph.springernature.com/pub.10.1007/s11912-004-0023-4

9 August 2017

0 references

cites work

Regulation of JNK signaling by GSTp

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Glutathione S-transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Increased constitutive c-Jun N-terminal kinase signaling in mice lacking glutathione S-transferase Pi

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Role of multidrug resistance protein 1 (MRP1) and glutathione S-transferase A1-1 in alkylating agent resistance. Kinetics of glutathione conjugate formation and efflux govern differential cellular sensitivity to chlorambucil versus melphalan toxicit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Glutathione conjugation of the cytostatic drug ifosfamide and the role of human glutathione S-transferases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Role of glutathione S-transferase P1, P-glycoprotein and multidrug resistance-associated protein 1 in acquired doxorubicin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Glutathione-S-transferase activates novel alkylating agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Resistance to phorbol 12-myristate 13-acetate-induced cell growth arrest in an HL60 cell line chronically exposed to a glutathione S-transferase π inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Reversal of multiple drug resistance in cholangiocarcinoma by the glutathione S-transferase-pi-specific inhibitor O1-hexadecyl-gamma-glutamyl-S-benzylcysteinyl-D-phenylglycine ethylester.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

A novel missense mutation in the gamma-glutamylcysteine synthetase catalytic subunit gene causes both decreased enzymatic activity and glutathione production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Novel class of bivalent glutathione S-transferase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Brief history of glyoxalase I and what we have learned about metal ion-dependent, enzyme-catalyzed isomerizations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Advances in glyoxalase research. Glyoxalase expression in malignancy, anti-proliferative effects of methylglyoxal, glyoxalase I inhibitor diesters and S-D-lactoylglutathione, and methylglyoxal-modified protein binding and endocytosis by the advanced

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

A possible regulatory role of glyoxalase I in cell viability of human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Methylglyoxal, an endogenous aldehyde, crosslinks DNA polymerase and the substrate DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Catalytic mechanism of glyoxalase I: a theoretical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Nitric oxide and the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Chemical basis of inflammation-induced carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

The multifaceted roles of nitric oxide in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Control of nitric oxide production by transforming growth factor-beta1: mechanistic insights and potential relevance to human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

The altered tumoricidal capacity of macrophages isolated from tumor-bearing mice is related to reduce expression of the inducible nitric oxide synthase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Nitric oxide synthase activity in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

The biochemistry and physiology of S-nitrosothiols

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

The role of glutathione in the transport and catabolism of nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Nitric oxide induces cyclooxygenase expression and inhibits cell growth in colon cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Annexins and membrane dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

A molecular compendium of genes expressed in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Degradation of extracellular matrix protein tenascin-C by cathepsin B: an interaction involved in the progression of gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Annexin II overexpression correlates with stromal tenascin-C overexpression: a prognostic marker in colorectal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Annexin II: a plasminogen-plasminogen activator co-receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Arsenic trioxide, retinoic acid and Ara-c regulated the expression of annexin II on the surface of APL cells, a novel co-receptor for plasminogen/tissue plasminogen activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Inactivation of annexin II tetramer by S-nitrosoglutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Nitration of annexin II tetramer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-004-0023-4

Nitric oxide synthase activity in human gynecological cancer

21 January 2018

1 reference

12 December 2020

Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases

1 reference

12 December 2020

Glyoxalase I is involved in resistance of human leukemia cells to antitumor agent-induced apoptosis

1 reference

12 December 2020

Formation of strand breaks and interstrand cross-links in DNA by methylglyoxal

1 reference

12 December 2020

Cellular response to a glutathione S-transferase P1-1 activated prodrug.

1 reference

12 December 2020

Expression of nitric oxide synthase in human central nervous system tumors.

1 reference

12 December 2020

Glutathione transferases as markers of preneoplasia and neoplasia

1 reference

12 December 2020

Metabolism of S-nitrosoglutathione by endothelial cells

1 reference

12 December 2020

Role of hydrophobic interactions in binding S-(N-aryl/alkyl-N-hydroxycarbamoyl)glutathiones to the active site of the antitumor target enzyme glyoxalase I

1 reference

12 December 2020

Glutathione based approaches to improving cancer treatment

1 reference

12 December 2020

Glutathione-associated enzymes in anticancer drug resistance.

1 reference

12 December 2020

Glutathione peptidomimetic drug modulator of multidrug resistance-associated protein

1 reference

12 December 2020

Identification of 5-fluorouracil-inducible target genes using cDNA microarray profiling.

1 reference

12 December 2020

Protection by glutathione against the antiproliferative effects of nitric oxide. Dependence on kinetics of no release

1 reference

12 December 2020

Isozyme-specific glutathione S-transferase inhibitors potentiate drug sensitivity in cultured human tumor cell lines

1 reference

12 December 2020

Efficacy of a glutathione S-transferase pi-activated prodrug in platinum-resistant ovarian cancer cells

1 reference

12 December 2020

Loss of annexin II heavy and light chains in prostate cancer and its precursors.

1 reference

12 December 2020

Inhibitors of glutathione S-transferases as therapeutic agents

1 reference

12 December 2020

Antitumour activity of S-p-bromobenzylglutathione cyclopentyl diester in vitro and in vivo

1 reference

12 December 2020

Mechanism of nitric oxide release from S-nitrosothiols

1 reference

12 December 2020

Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GSTpi) influences cell proliferation pathways

1 reference

12 December 2020

Selective activation of apoptosis program by S-p-bromobenzylglutathione cyclopentyl diester in glyoxalase I-overexpressing human lung cancer cells

1 reference

12 December 2020

Purification and characterisation of glyoxalase II from human red blood cells

1 reference

12 December 2020

Tumor efficacy and bone marrow-sparing properties of TER286, a cytotoxin activated by glutathione S-transferase.

1 reference

12 December 2020

The glutathione system in alkylator resistance.

1 reference

12 December 2020

Phase I study of TLK286 (glutathione S-transferase P1-1 activated glutathione analogue) in advanced refractory solid malignancies

1 reference

12 December 2020

Annexin II expression is reduced or lost in prostate cancer cells and its re-expression inhibits prostate cancer cell migration

1 reference

12 December 2020

10.1007/S11912-004-0023-4

Identifiers

DOI

1 reference

9 August 2017

1 reference

PubMed ID

14751089