(Q35648435)

9 August 2017

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title

Drug discovery in academia. (English)

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9 August 2017

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Verkman AS

1

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9 August 2017

publication date

1 March 2004

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American Journal of Physiology - Cell Physiology

9 August 2017

published in

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9 August 2017

volume

286

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9 August 2017

issue

3

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9 August 2017

page(s)

C465-74

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Current state and perspectives of 3D-QSAR.

9 August 2017

cites work

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https://api.crossref.org/works/10.1152%2FAJPCELL.00397.2003

Pharmacophore modeling as an efficient tool in the discovery of novel noncompetitive AMPA receptor antagonists

21 January 2018

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Novel miniaturized systems in high-throughput screening

21 January 2018

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Hit and lead generation: beyond high-throughput screening

21 January 2018

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Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

21 January 2018

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The price of innovation: new estimates of drug development costs

21 January 2018

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Stategic trends in the drug industry

21 January 2018

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Development of therapeutics: opportunities within complementary and alternative medicine

21 January 2018

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Green fluorescent protein-based halide indicators with improved chloride and iodide affinities

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPCELL.00397.2003

Cell-based assay for high-throughput quantitative screening of CFTR chloride transport agonists

21 January 2018

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Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds

21 January 2018

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Combinatorial compound libraries for drug discovery: an ongoing challenge

21 January 2018

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Virtual screening of virtual libraries

21 January 2018

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High-throughput screening: new technology for the 21st century

21 January 2018

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Mechanism and cellular applications of a green fluorescent protein-based halide sensor

21 January 2018

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Submucosal gland secretions in airways from cystic fibrosis patients have normal [Na(+)] and pH but elevated viscosity

21 January 2018

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Long-wavelength iodide-sensitive fluorescent indicators for measurement of functional CFTR expression in cells

21 January 2018

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Predicting therapeutic value in the lead optimization phase of drug discovery

21 January 2018

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A guide to drug discovery: Target selection in drug discovery

21 January 2018

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The role of absorption, distribution, metabolism, excretion and toxicity in drug discovery

21 January 2018

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Theoretical property predictions

21 January 2018

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Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion.

21 January 2018

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High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening

21 January 2018

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Fluorescent chloride indicators to assess the efficacy of CFTR cDNA delivery

21 January 2018

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Trends in development and approval times for new therapeutics in the United States

21 January 2018

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Pharmacophore and quantitative structure-activity relationship modeling: complementary approaches for the rationalization and prediction of UDP-glucuronosyltransferase 1A4 substrate selectivity.

21 January 2018

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Whole-body autoradiography in drug discovery

21 January 2018

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Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain

21 January 2018

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Prevention of toxin-induced intestinal ion and fluid secretion by a small-molecule CFTR inhibitor

21 January 2018

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Structure-activity relationship approaches and applications

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPCELL.00397.2003

Rational principles of compound selection for combinatorial library design

21 January 2018

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Pharmacophore discovery--lessons learned

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPCELL.00397.2003

Crystallographic and energetic analysis of binding of selected anions to the yellow variants of green fluorescent protein

21 January 2018

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Nanomolar affinity small molecule correctors of defective Delta F508-CFTR chloride channel gating.

21 January 2018

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

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10.1152/AJPCELL.00397.2003

21 January 2018

Identifiers

DOI

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9 August 2017

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