(Q35653564)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22291644%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Metabolism of oxycodone in human hepatocytes from different age groups and prediction of hepatic plasma clearance (English)

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21 January 2020

4

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21 January 2020

author name string

Timo Korjamo

1

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21 January 2020

Ari Tolonen

2

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21 January 2020

Veli-Pekka Ranta

3

1 reference

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21 January 2020

Hannu Kokki

5

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21 January 2020

publication date

1 January 2011

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Frontiers in Pharmacology

21 January 2020

published in

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21 January 2020

volume

2

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21 January 2020

page(s)

87

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Methodological uncertainty in quantitative prediction of human hepatic clearance from in vitro experimental systems.

21 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Prediction of hepatic clearance in human from in vitro data for successful drug development

12 July 2018

1 reference

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Involvement of the pyrilamine transporter, a putative organic cation transporter, in blood-brain barrier transport of oxycodone

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data: reaching a consensus on values of human microsomal protein and hepatocellularity per gram of liver.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: role of circulating active metabolites

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Ontogeny of hepatic and renal systemic clearance pathways in infants: part II.

12 July 2018

1 reference

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2000 CDC Growth Charts for the United States: methods and development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Multisite kinetic models for CYP3A4: simultaneous activation and inhibition of diazepam and testosterone metabolism.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Liposolubility and protein binding of oxycodone in vitro.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Pharmacokinetics and ventilatory effects of intravenous oxycodone in postoperative children [see comments]

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

A formula to estimate the approximate surface area if height and weight be known. 1916.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

The pharmacokinetics of oxycodone after intravenous injection in adults

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Single-dose and steady-state pharmacokinetics and pharmacodynamics of oxycodone in patients with cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

The pharmacokinetics and metabolism of oxycodone after intramuscular and oral administration to healthy subjects

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Geometric method for measuring body surface area: a height-weight formula validated in infants, children, and adults

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Oxycodone induces overexpression of P-glycoprotein (ABCB1) and affects paclitaxel's tissue distribution in Sprague Dawley rats

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Misuse of the well-stirred model of hepatic drug clearance.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Evaluation of cryopreserved human hepatocytes as an alternative in vitro system to microsomes for the prediction of metabolic clearance.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

A mechanistic approach for the scaling of clearance in children.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

In vivo blood-brain barrier transport of oxycodone in the rat: indications for active influx and implications for pharmacokinetics/pharmacodynamics.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Changes in liver volume from birth to adulthood: a meta-analysis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Marked variation in oxycodone pharmacokinetics in infants

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Pharmacokinetics of oxycodone after intravenous, buccal, intramuscular and gastric administration in children

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Effects of blocking CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Pharmacokinetic comparison of intravenous and intranasal administration of oxycodone.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

The pharmacokinetics of oxycodone in uremic patients undergoing renal transplantation.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251796

Basic anatomical and physiological data for use in radiological protection: reference values. A report of age- and gender-related differences in the anatomical and physiological characteristics of reference individuals. ICRP Publication 89

25 September 2018

1 reference

12 December 2020

Population pharmacokinetics of oxycodone in children 6 months to 7 years old

1 reference

12 December 2020

Comparison of oxycodone pharmacokinetics after buccal and sublingual administration in children

1 reference

12 December 2020

Use of hepatocytes to assess the contribution of hepatic uptake to clearance in vivo

1 reference

12 December 2020

Comparison of intrinsic clearances in human liver microsomes and suspended hepatocytes from the same donor livers: clearance-dependent relationship and implications for prediction of in vivo clearance

1 reference

12 December 2020

Does co-administration of paroxetine change oxycodone analgesia: An interaction study in chronic pain patients

1 reference

12 December 2020

Determination of the Serum Protein Binding of Oxycodone and Morphine Using Ultrafiltration

1 reference

12 December 2020

Identifiers

DOI

10.3389/FPHAR.2011.00087

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22291644%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22291644%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PubMed publication ID

22291644

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22291644%20AND%20SRC:MED&resulttype=core&format=json