(Q35657526)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22171009%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Structure-based design of conformation- and sequence-specific antibodies against amyloid β (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22171009%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22171009%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Joseph M Perchiacca

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22171009%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Ali Reza A Ladiwala

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22171009%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Moumita Bhattacharya

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22171009%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

language of work or name

English

0 references

publication date

14 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22171009%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

18 January 2020

number of pages

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22171009%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22171009%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22171009%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

84-89

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22171009%20AND%20SRC:MED&resulttype=core&format=json

Polyphenolic glycosides and aglycones utilize opposing pathways to selectively remodel and inactivate toxic oligomers of amyloid β.

18 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Solid-state NMR studies of amyloid fibril structure

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Aromatic small molecules remodel toxic soluble oligomers of amyloid beta through three independent pathways

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Resveratrol selectively remodels soluble oligomers and fibrils of amyloid Abeta into off-pathway conformers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrils

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Identifying the amylome, proteins capable of forming amyloid-like fibrils

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Conformational targeting of fibrillar polyglutamine proteins in live cells escalates aggregation and cytotoxicity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Structural characterization of a soluble amyloid beta-peptide oligomer.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Structural differences between Abeta(1-40) intermediate oligomers and fibrils elucidated by proteolytic fragmentation and hydrogen/deuterium exchange

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

C-terminal peptides coassemble into Abeta42 oligomers and protect neurons against Abeta42-induced neurotoxicity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's beta-amyloid peptide.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Comprehensive analysis of the factors contributing to the stability and solubility of autonomous human VH domains

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Prion recognition elements govern nucleation, strain specificity and species barriers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Atomic structures of amyloid cross-beta spines reveal varied steric zippers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Amyloid of the prion domain of Sup35p has an in-register parallel beta-sheet structure

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Protein misfolding, functional amyloid, and human disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

3D structure of Alzheimer's amyloid-beta(1-42) fibrils

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Protein production by auto-induction in high density shaking cultures

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Template-assisted filament growth by parallel stacking of tau.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Molecular basis of a yeast prion species barrier

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Propagating structure of Alzheimer's beta-amyloid(10-35) is parallel beta-sheet with residues in exact register

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252897

Vaccination with soluble Abeta oligomers generates toxicity-neutralizing antibodies.

27 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111232108

Conformational Abs recognizing a generic amyloid fibril epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111232108

Monoclonal antibodies that target pathological assemblies of Abeta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111232108

Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111232108

Direct in vivo intracellular selection of conformation-sensitive antibody domains targeting Alzheimer's amyloid-beta oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111232108

Anti-oligomeric Abeta single-chain variable domain antibody blocks Abeta-induced toxicity against human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111232108

Structural and dynamic features of Alzheimer's Abeta peptide in amyloid fibrils studied by site-directed spin labeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111232108

Design and characterization of a membrane permeable N-methyl amino acid-containing peptide that inhibits Abeta1-40 fibrillogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111232108

Structure-function relationships for inhibitors of beta-amyloid toxicity containing the recognition sequence KLVFF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111232108

Toward molecular dissection of PrPC-PrPSc interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111232108

Determination of antibody affinity by ELISA. Theory

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111232108

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111232108

Self-assembly of Abeta(1-42) into globular neurotoxins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111232108

Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22171009

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1111232108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22171009%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22171009%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

22171009

1 reference