(Q35660108)

English

Multitarget fatty acid amide hydrolase/cyclooxygenase blockade suppresses intestinal inflammation and protects against nonsteroidal anti-inflammatory drug-dependent gastrointestinal damage.

scientific article published on 10 March 2015

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25757568%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Multitarget fatty acid amide hydrolase/cyclooxygenase blockade suppresses intestinal inflammation and protects against nonsteroidal anti-inflammatory drug-dependent gastrointestinal damage (English)

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2 March 2020

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Andrea Armirotti

4

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2 March 2020

6

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2 March 2020

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Oscar Sasso

1

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2 March 2020

Marco Migliore

2

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2 March 2020

Damien Habrant

3

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2 March 2020

Clara Albani

5

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2 March 2020

Guillermo Moreno-Sanz

7

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2 March 2020

Rita Scarpelli

8

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2 March 2020

Daniele Piomelli

9

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2 March 2020

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10 March 2015

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2 March 2020

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Europe PubMed Central

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2 March 2020

29

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2 March 2020

6

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2 March 2020

2616-2627

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25757568%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

NSAID-gastroenteropathy: new aspects of pathogenesis and prevention

1 reference

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Peripheral gating of pain signals by endogenous lipid mediators

1 reference

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Peripheral inflammatory hyperalgesia depends on the COX increase in the dorsal root ganglion

1 reference

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27 July 2018

Identification and characterization of carprofen as a multitarget fatty acid amide hydrolase/cyclooxygenase inhibitor

1 reference

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Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health

1 reference

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27 July 2018

Ulcerative colitis impairs the acylethanolamide-based anti-inflammatory system reversal by 5-aminosalicylic acid and glucocorticoids

1 reference

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27 July 2018

(R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

Endocannabinoid oxygenation by cyclooxygenases, lipoxygenases, and cytochromes P450: cross-talk between the eicosanoid and endocannabinoid signaling pathways

1 reference

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27 July 2018

Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor

1 reference

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27 July 2018

NSAID gastropathy and enteropathy: distinct pathogenesis likely necessitates distinct prevention strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone (SAB378), a peripherally restricted cannabinoid CB1/CB2 receptor agonist, inhibits gastrointestinal motility but has no effect on experimental colitis in mice

1 reference

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27 July 2018

Crystal Structure of Fatty Acid Amide Hydrolase Bound to the Carbamate Inhibitor URB597: Discovery of a Deacylating Water Molecule and Insight into Enzyme Inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

Anandamide suppresses proliferation and cytokine release from primary human T-lymphocytes mainly via CB2 receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

Novel endogenous N-acyl glycines identification and characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

The case for the development of novel analgesic agents targeting both fatty acid amide hydrolase and either cyclooxygenase or TRPV1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

Synergy between enzyme inhibitors of fatty acid amide hydrolase and cyclooxygenase in visceral nociception

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

Synergistic antinociception by the cannabinoid receptor agonist anandamide and the PPAR-alpha receptor agonist GW7647.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

Structural and functional basis of cyclooxygenase inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

A biosynthetic pathway for anandamide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

A FAAH-regulated class of N-acyl taurines that activates TRP ion channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

Differential expression of cannabinoid receptors in the human colon: cannabinoids promote epithelial wound healing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

The endogenous cannabinoid system protects against colonic inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

Animal models of inflammatory bowel disease: an overview

1 reference

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27 July 2018

Modulation of anxiety through blockade of anandamide hydrolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

27 July 2018

Enterohepatic circulation: physiological, pharmacokinetic and clinical implications

1 reference

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27 July 2018

The immunology of mucosal models of inflammation

1 reference

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27 July 2018

Structure-based design of COX-2 selectivity into flurbiprofen

1 reference

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27 July 2018

Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

1 reference

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27 July 2018

Pharmacology of a selective cyclooxygenase-2 inhibitor, L-745,337: a novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and nonhuman primate stomach.

1 reference

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27 July 2018

Use of colonic eicosanoid concentrations as predictors of relapse in ulcerative colitis: double blind placebo controlled study on sulphasalazine maintenance treatment

1 reference

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27 July 2018

Role of prostaglandins in gastroduodenal mucosal protection.

1 reference

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27 July 2018

The Disposition and Metabolism of Flurbiprofen in Several Species Including Man

1 reference

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27 July 2018

Distinct modulation of human myeloid and plasmacytoid dendritic cells by anandamide in multiple sclerosis

1 reference

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25 September 2018

Peripheral FAAH inhibition causes profound antinociception and protects against indomethacin-induced gastric lesions

1 reference

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25 September 2018

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1 reference

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Omega-3 fatty acid-derived mediators 17(R)-hydroxy docosahexaenoic acid, aspirin-triggered resolvin D1 and resolvin D2 prevent experimental colitis in mice.

1 reference

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25 September 2018

Prostaglandins and inflammation

1 reference

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25 September 2018

The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447230

25 September 2018

GW0742, a selective PPAR-beta/delta agonist, contributes to the resolution of inflammation after gut ischemia/reperfusion injury

1 reference

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1 reference

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25 September 2018

Peroxisome proliferator-activated receptor-alpha modulates the anti-inflammatory effect of glucocorticoids in a model of inflammatory bowel disease in mice

1 reference

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25 September 2018

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1 reference

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25 September 2018

Inhibition of fatty acid amide hydrolase, a key endocannabinoid metabolizing enzyme, by analogues of ibuprofen and indomethacin.

1 reference

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25 September 2018

Gastric tolerability and prolonged prostaglandin inhibition in the brain with a nitric oxide-releasing flurbiprofen derivative, NCX-2216 [3-[4-(2-fluoro-alpha-methyl-[1,1'-biphenyl]-4-acetyloxy)-3-methoxyphenyl]-2-propenoic acid 4-nitrooxy butyl est

1 reference

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25 September 2018

Design, synthesis, and structure-activity relationships of alkylcarbamic acid aryl esters, a new class of fatty acid amide hydrolase inhibitors.

1 reference

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25 September 2018

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1 reference

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25 September 2018

Control of pain initiation by endogenous cannabinoids.

1 reference

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25 September 2018

Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease

1 reference

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25 September 2018

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Guttate psoriasis induced by infliximab in a child with Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25757568

12 December 2020

based on heuristic

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Identifiers

10.1096/FJ.15-270637

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25757568%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25757568%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25757568%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

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