(Q34774063)

4 August 2017

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title

Enterohepatic circulation: physiological, pharmacokinetic and clinical implications (English)

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4 August 2017

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Michael S Roberts

1

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4 August 2017

Beatrice M Magnusson

series ordinal

2

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4 August 2017

Frank J Burczynski

series ordinal

3

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4 August 2017

Michael Weiss

series ordinal

4

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4 August 2017

1 January 2002

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Clinical Pharmacokinetics

4 August 2017

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4 August 2017

41

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4 August 2017

751-790

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4 August 2017

10

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https://scigraph.springernature.com/pub.10.2165/00003088-200241100-00005

4 August 2017

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cites work

Disposition of the selective cholesterol absorption inhibitor ezetimibe in healthy male subjects

1 reference

12 December 2020

Biliary excretion of some diquaternary ammonium cations in the rat, guinea pig and rabbit

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12 December 2020

Metabolism of drugs and other xenobiotics in the gut lumen and wall

1 reference

12 December 2020

Hypercholeresis induced by ursodeoxycholic acid and 7-ketolithocholic acid in the rat: possible role of bicarbonate transport

1 reference

12 December 2020

Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity

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12 December 2020

Noncompartmental area under the curve determinations for drugs that cycle in the bile.

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12 December 2020

In liver transplantation, T tube bile represents total bile flow: physiological and scintigraphic studies on biliary secretion of organic anions.

1 reference

12 December 2020

A mathematical model of the kinetics and tissue distribution of 2-fluoro-beta-alanine, the major catabolite of 5-fluorouracil.

1 reference

12 December 2020

Estimation of area under the curve for drugs subject to enterohepatic cycling

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12 December 2020

Pharmacokinetics of troglitazone, an antidiabetic agent: prediction of in vivo stereoselective sulfation and glucuronidation from in vitro data.

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12 December 2020

Hepatobiliary transport

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12 December 2020

Membrane localization of the electrogenic cation transporter rOCT1 in rat liver

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12 December 2020

Reduced activity of the electron transport chain in liver mitochondria isolated from rats with secondary biliary cirrhosis

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12 December 2020

The role of cytoplasmic proteins in hepatic bile acid transport

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12 December 2020

Molecular weight as a factor in the excretion of monoquaternary ammonium cations in the bile of the rat, rabbit and guinea pig

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12 December 2020

The multiple indicator-dilution method for the study of enzyme heterogeneity in liver: theoretical basis

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12 December 2020

Hepatic transport of a fluorescent stearate derivative: electrochemical driving forces in intact rat liver

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12 December 2020

Metabolism of foreign compounds by gastrointestinal microorganisms

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12 December 2020

The Enhancement of Maximal Bilirubin Excretion with Taurocholate–Induced Increments in Bile Flow

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12 December 2020

Enterohepatic recirculation of the new antihypertensive drug UP 269-6 in humans. A possible model to account for multiple plasma peaks.

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12 December 2020

Enantioselective local disposition of semotiadil (R-enantiomer) and levosemotiadil (S-enantiomer) in perfused rat liver.

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12 December 2020

Structure-hepatic disposition relationships for cationic drugs in isolated perfused rat livers: transmembrane exchange and cytoplasmic binding process

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12 December 2020

Clinical pharmacokinetics of mycophenolate mofetil

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12 December 2020

Comparative toxicology of chlordecone (Kepone) in humans and experimental animals

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12 December 2020

Membrane transport as a determinant of the hepatic elimination of drugs and metabolites

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12 December 2020

The pathophysiology of cholestasis with special reference to primary biliary cirrhosis

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12 December 2020

Moment analysis of stereoselective enterohepatic circulation and unidirectional chiral inversion of ketoprofen enantiomers in rat.

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12 December 2020

Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport.

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12 December 2020

Hepatic uptake and biliary excretion of d-tubocurarine and trimethyltubocurarine in the rat in vivo and in isolated perfused rat livers

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12 December 2020

The distribution of theta-class glutathione S-transferases in the liver and lung of mouse, rat and human

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12 December 2020

Comparison of the disposition of hepatically-generated morphine-3-glucuronide and morphine-6-glucuronide in isolated perfused liver from the guinea pig

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12 December 2020

The binding of fatty acids to cytoplasmic proteins: Binding to Z protein in liver and other tissues of the rat

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12 December 2020

Interactions Between Oral Contraceptives and Antifungals/Antibacterials

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12 December 2020

Biliary excretion and intestinal metabolism of progesterone and estrogens in man.

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12 December 2020

Effect of 3-methylcholanthrene on the biliary excretion of bromsulphthalein and eosine in newborn rats

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12 December 2020

The effect of selective bowel decontamination on the pharmacokinetics of mycophenolate mofetil in liver transplant recipients.

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12 December 2020

Pharmacokinetics and pharmacodynamics of gliclazide in Caucasians and Australian Aborigines with type 2 diabetes

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12 December 2020

Molecular and physical mechanisms of first-pass extraction

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12 December 2020

Expression and function of P-glycoprotein in rats with glycerol-induced acute renal failure

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12 December 2020

Clinical consequences of the biphasic elimination kinetics for the diuretic effect of furosemide and its acyl glucuronide in humans

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12 December 2020

Secretion of organic anions by hepatocytes: involvement of homologues of the multidrug resistance protein.

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12 December 2020

Relationship between chemical structure and physicochemical properties of series of bulky organic cations and their hepatic uptake and biliary excretion rates

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12 December 2020

Biliary secretion of glutathione and of glutathione-metal complexes

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12 December 2020

Intrahepatic cholestasis as a canalicular motility disorder. Evidence using cytochalasin

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12 December 2020

Effect of cyclosporine withdrawal on mycophenolic acid pharmacokinetics in kidney transplant recipients with deteriorating renal function: preliminary report

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12 December 2020

Structure-pharmacokinetics relationship of quaternary ammonium compounds. Correlation of physicochemical and pharmacokinetic parameters.

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12 December 2020

Biliary Excretion of Drugs and Other Xenobiotics

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12 December 2020

Review article: new insights into the mechanisms of hepatic transport and bile secretion

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12 December 2020

Identity of hepatic membrane transport systems for bile salts, phalloidin, and antamanide by photoaffinity labeling

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12 December 2020

Physicochemical and immunohistological studies of a sulfobromophthalein- and bilirubin-binding protein from rat liver plasma membranes

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12 December 2020

Zonation of hepatic cytochrome P-450 expression and regulation

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12 December 2020

Treatment of chlordecone (Kepone) toxicity with cholestyramine. Results of a controlled clinical trial

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12 December 2020

Structure-pharmacokinetics relationship of quaternary ammonium compounds

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12 December 2020

Physiologic and metabolic influences on enterohepatic recirculation: simulations based upon the disposition of valproic acid in the rat.

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12 December 2020

Hepatic bile acid uptake: effect of conjugation, hydroxyl and keto groups, and albumin binding

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12 December 2020

Biliary excretion and enterohepatic recirculation of morphine-3-glucuronide in rats

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12 December 2020

Minimal biliary excretion and enterohepatic recirculation of lormetazepam in man as investigated by a new nasobiliary drainage technique

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12 December 2020

The evaluation of the drug-metabolizing capacity in patients with diabetes mellitus

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12 December 2020

Both cMOAT/MRP2 and another unknown transporter(s) are responsible for the biliary excretion of glucuronide conjugate of the nonpeptide angiotensin II antagonist, telmisaltan

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12 December 2020

A time-lag model for pharmacokinetics of drugs subject to enterohepatic circulation

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12 December 2020

Enterohepatic circulation of oestriol: a study of the effects of ampicillin on plasma oestriol levels

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12 December 2020

Erythrocyte alterations correlate with CCl4 and biliary obstruction-induced liver damage in the rat

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12 December 2020

Excretion and biotransformation of alfentanil and sufentanil in rats and dogs

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12 December 2020

A new method for quantitating intracellular transport: application to the thyroid hormone 3,5,3'-triiodothyronine

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12 December 2020

Transport polarity of hepatocytes

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12 December 2020

Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals

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12 December 2020

Cytoplasmic binding and disposition kinetics of diclofenac in the isolated perfused rat liver

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12 December 2020

Enterohepatic circulation of lorazepam and acetaminophen conjugates in ponies

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12 December 2020

Biliary excretion of acetaminophen in ureter-ligated rats

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12 December 2020

Effect modelling for drugs undergoing enterohepatic circulation

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12 December 2020

The pathobiology of biliary epithelia

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12 December 2020

Cholestyramine as an antidote against paracetamol-induced hepato- and nephrotoxicity in the rat

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12 December 2020

Pharmacology and pharmacokinetics of amiodarone

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12 December 2020

Studies on phenolic steroids in human subjects. II. The metabolic fate and hepato-biliary-enteric circulation of C14-estrone and C14-estradiol in women

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12 December 2020

Pharmacokinetics of tolfenamic acid: Disposition in bile, blood and urine after intravenous administration to man

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12 December 2020

Maximal biliary transport of sulfobromophthalein in patients with a T-tube placed in the common bile duct

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12 December 2020

Gastric and biliary excretion of meperidine in man

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12 December 2020

Lack of evidence for vesicle trafficking of fluorescent bile salts in rat hepatocyte couplets

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12 December 2020

Uptake and glutathione conjugation of ethacrynic acid and efflux of the glutathione adduct by periportal and perivenous rat hepatocytes.

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12 December 2020

Functional implications of liver cell heterogeneity.

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12 December 2020

Hepatic microvascular changes associated with development of liver fibrosis and cirrhosis

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12 December 2020

Ligandin: a Hepatic Protein which Binds Steroids, Bilirubin, Carcinogens and a Number of Exogenous Organic Anions

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12 December 2020

Immunohistochemical localization of glutathione S-transferases in livers of untreated rats.

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12 December 2020

Comparison of the effects of two-thirds hepatectomy and bile duct ligation on hepatic excretory function.

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12 December 2020

Multiple-dose lorazepam kinetics: shuttling of lorazepam glucuronide between the circulation and the gut during day- and night-time dosing intervals in response to feeding.

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12 December 2020

The incidence of gallstones and their correlation with other diseases

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12 December 2020

Mechanism of secretion of biliary lipids: Role of a microtubular system in hepatocellular transport of biliary lipids in the rat

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12 December 2020

Functional expression of the rat liver canalicular isoform of the multidrug resistance-associated protein

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12 December 2020

The role of the hepatic endoplasmic reticulum in the biliary excretion of foreign compounds by the rat. The effect of phenobarbitone and SKF 525-A (diethylaminoethyl diphenylpropylacetate)

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12 December 2020

Conjugation reactions in hepatocytes isolated from streptozotocin-induced diabetic rats

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12 December 2020

Physiochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH.

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12 December 2020

The disposition of sulindac

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12 December 2020

Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions

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12 December 2020

Tauroursodeoxycholic acid stimulates hepatocellular exocytosis and mobilizes extracellular Ca++ mechanisms defective in cholestasis

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12 December 2020

Disposition analysis by fast inverse Laplace transform (FILT)

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12 December 2020

Biliary excretion of chromium in the rat: a role of glutathione

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12 December 2020

Interpretation of area under the curve measurements for drugs subject to enterohepatic cycling

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12 December 2020

A new analysis method for disposition kinetics of enterohepatic circulation of diclofenac in rats.

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12 December 2020

Glucuronidation in humans. Pharmacogenetic and developmental aspects

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12 December 2020

Fetal hepatic drug elimination

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12 December 2020

The plasma removal on indocyanine green and sulfobromophthalein: effect of dosage and blocking agents

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12 December 2020

Pharmacokinetic interpretation of the enterohepatic recirculation and first-pass elimination of morphine in the rat

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12 December 2020

The enterohepatic circulation of bile acids in man.

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12 December 2020

Induction of UDP-glycosyltransferase family 1 genes in rat liver: different patterns of mRNA expression with two inducers, 3-methylcholanthrene and beta-naphthoflavone

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12 December 2020

Biliary excretion of chlorthalidone in humans.

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12 December 2020

Influence of side-chain charge on hepatic transport of bile acids and bile acid analogues

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12 December 2020

Hepatic extraction of bile acids in rats

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12 December 2020

Inhibition of rat and human glutathione S-transferase isoenzymes by ethacrynic acid and its glutathione conjugate.

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12 December 2020

Recent advances in bilirubin metabolism research: the molecular mechanism of hepatocyte bilirubin transport and its clinical relevance

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12 December 2020

Localization of CYP1A1 and CYP1A2 messenger RNA in normal human liver and in hepatocellular carcinoma by in situ hybridization

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12 December 2020

On the localisation of d-tubocurarine in rat liver lysosomes in vivo by electron microscopy and subcellular fractionation

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12 December 2020

Pharmacokinetics of glibenclamide and its metabolites in diabetic patients with impaired renal function.

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12 December 2020

Mechanisms of time-dependent kinetics of diltiazem in the isolated perfused rat liver

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12 December 2020

Restricted expression of the erythroid/brain glucose transporter isoform to perivenous hepatocytes in rats. Modulation by glucose

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12 December 2020

Hepatic disposition of the acyl glucuronide 1-O-gemfibrozil-beta-D-glucuronide: effects of clofibric acid, acetaminophen, and acetaminophen glucuronide

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12 December 2020

Current concepts on hepatic transport of drugs

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12 December 2020

Biliary excretion of 3 H-digitoxin: modification by bile salts and phenobarbital

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12 December 2020

THE INFLUENCE OF CHOLESTYRAMINE ON THE INTESTINAL ABSORPTION OF GLYCOCHOLIC ACID

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12 December 2020

Altered hepatobiliary disposition of acetaminophen glucuronide in isolated perfused livers from multidrug resistance-associated protein 2-deficient TR(-) rats

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12 December 2020

Heterologous expression and kinetic characterization of human cytochromes P-450: validation of a pharmaceutical tool for drug metabolism research

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12 December 2020

Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data

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12 December 2020

A reversible clearance model for the enterohepatic circulation of drug and conjugate metabolite pair.

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12 December 2020

Analysis in the rat of 4-hydroxynonenal metabolites excreted in bile: evidence of enterohepatic circulation of these byproducts of lipid peroxidation

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12 December 2020

Bile acid transport in cultured rat hepatocytes

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12 December 2020

Metabolism and transport of amphipathic molecules in analbuminemic rats and human subjects

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12 December 2020

Biochemistry of bile secretion

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12 December 2020

The influence of conjugation of cholic acid on its uptake and secretion: hepatic extraction of taurocholate and cholate in the dog

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12 December 2020

Unequal disposition of enantiomers of the organic cation oxyphenonium in the rat isolated perfused liver

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12 December 2020

Carbon tetrachloride depresses hepatic phospholipid synthesis in rats

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12 December 2020

Hepatic Na(+)-dicarboxylate cotransport: identification, characterization, and acinar localization

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12 December 2020

STUDIES ON PHENOLIC STEROIDS IN HUMAN SUBJECTS. VII. METABOLIC FATE OF ESTRIOL AND ITS GLUCURONIDE.

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12 December 2020

MRP3, an organic anion transporter able to transport anti-cancer drugs

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12 December 2020

Contribution of lysosomal trapping to the total tissue uptake of psychotropic drugs

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12 December 2020

Vitamin D metabolism and mechanisms of calcium transport.

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12 December 2020

Role of plasma membrane ligand-binding proteins in the hepatocellular uptake of albumin-bound organic anions.

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12 December 2020

Biliary Excretion of Drugs in Man

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12 December 2020

Intact hepatocyte theory of impaired drug metabolism in experimental cirrhosis in the rat

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12 December 2020

Mechanisms of cholestasis

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12 December 2020

Lack of zonal uptake of estrone sulfate in enriched periportal and perivenous isolated rat hepatocytes

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12 December 2020

Role of glutathione and hepatic glutathione S-transferase in the biliary excretion of methyl mercury, cadmium and zinc: a study with enzyme inducers and glutathione depletors.

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12 December 2020

Influence of poly(DL-lactide) nanocapsules on the biliary clearance and enterohepatic circulation of indomethacin in the rabbit

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12 December 2020

Intrahepatic cholestasis: a review of biochemical-pathological mechanisms

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12 December 2020

The metabolism of drugs by the gut flora

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12 December 2020

Biliary pharmacokinetics of sulbactam plus ampicillin in humans.

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12 December 2020

Kinetics of hepatic uptake of unconjugated bilirubin

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12 December 2020

The effect of alpha-naphthylisothiocyanate on bile secretion prior to and during the onset of cholestasis in the rat

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12 December 2020

Mechanisms of bile formation, hepatic uptake, and biliary excretion.

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12 December 2020

Cationic drug pharmacokinetics in diseased livers determined by fibrosis index, hepatic protein content, microsomal activity, and nature of drug

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12 December 2020

Mechanisms of cellular uptake of long chain free fatty acids

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12 December 2020

Concomitant administration of cholestyramine influences the absorption of troglitazone

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12 December 2020

Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver

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12 December 2020

Pharmacokinetics and bioavailability of cimetidine in humans.

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12 December 2020

Pharmacokinetics of the chemopreventive agent oltipraz and of its metabolite M3 in human subjects after a single oral dose

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12 December 2020

Efficiency of enterohepatic circulation, its determination and influence on drug bioavailability

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12 December 2020

Inhibitors of P-glycoprotein-mediated daunomycin transport in rat liver canalicular membrane vesicles

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12 December 2020

Pharmacokinetics of doxycycline reabsorption.

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12 December 2020

Structure, biochemistry, and assembly of epithelial tight junctions

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12 December 2020

Changes in phase I and phase II biotransformation with age in male Fischer 344 rat colon: relationship to colon carcinogenesis

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12 December 2020

Mechanisms underlying the prolonged duration of action of muscle relaxants caused by extrahepatic cholestasis

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12 December 2020

Third-generation cephalosporins: a critical evaluation

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12 December 2020

The possible role of enterohepatic cycling on bioavailability of norethisterone and gestodene in women using combined oral contraceptives

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12 December 2020

Acinar factors in drug processing: protein binding, futile cycling, and cosubstrate.

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12 December 2020

Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine

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12 December 2020

Serum collagenase activity reflects the amount of liver collagenase in chronic carbon tetrachloride-treated rats

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12 December 2020

Do intracellular organelles have any role in transport of bile acids by hepatocytes?

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12 December 2020

Enterohepatic recirculation of oestriol: inhibition by activated charcoal

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12 December 2020

Role of intrahepatic protein binding in the hepatobiliary extraction profile of cefixime in humans

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12 December 2020

INTRACELLULAR DISTRIBUTION OF TRITIATED BILIRUBIN DURING HEPATIC UPTAKE AND EXCRETION

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12 December 2020

Clinical pharmacokinetics of toremifene

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12 December 2020

Effect of cholestyramine on the disposition of pentachlorophenol in rhesus monkeys.

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12 December 2020

Cryptic adenosine triphosphatase activities in plasma membranes of CCl4-cirrhotic rats. Its modulation by changes in cholesterol/phospholipid ratios

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12 December 2020

Clinical pharmacokinetics of therapeutic bile acids.

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12 December 2020

General treatment of the enterohepatic recirculation of drugs and its influence on the area under the plasma level curves, bioavailability, and clearance.

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12 December 2020

Bile-salt-binding polypeptides in plasma membranes of hepatocytes revealed by photoaffinity labelling

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12 December 2020

Comparison of the effects of cholestyramine and aluminium hydroxide on the biliary bile acid excretion in rats. An experimental model for the depletion of bile acids in bile

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12 December 2020

Hepatic excretory function in the newborn rat.

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12 December 2020

Hepatic phase I and phase II biotransformations in quail and trout: comparison to other species commonly used in toxicity testing

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12 December 2020

The influence of insulin on drug passage into the tissues

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12 December 2020

Electron microscopic studies of normal and proliferated bile ductules.

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12 December 2020

Bile secretory characteristics of beta-muricholate and its taurine conjugate are similar to those of ursodeoxycholate in the rat

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12 December 2020

Biliary secretion of methadone and methadone metabolites in man.

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12 December 2020

Drug recirculation model with multiple cycles occurring at unequal time intervals

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12 December 2020

Biliary excretion of 17beta-estradiol 17beta-D-glucuronide is predominantly mediated by cMOAT/MRP2

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12 December 2020

Transport of cimetidine by the rat choroid plexus in vitro.

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12 December 2020

Hepatic uptake of foreign compounds: influence of acute extrahepatic biliary obstruction

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12 December 2020

Analysis of enterohepatic circulation of cefixime in rat by fast inverse Laplace transform (FILT).

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12 December 2020

Biliary excretion of organic anions in diabetic rats

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12 December 2020

Enterohepatic circulation of drugs

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12 December 2020

Metabolism of 4-C14-testosterone in human subjects. I. Distribution in bile, blood, feces and urine

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12 December 2020

The physiological disposition and metabolic fate of hydrocortisone in man.

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12 December 2020

Hepatic microcirculation in the perfused cirrhotic rat liver

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12 December 2020

Hepatic oleate uptake. Electrochemical driving forces in intact rat liver

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12 December 2020

Distribution of glutathione S-transferase isoforms in rat liver after induction by beta-naphthoflavone or 3-methylcholanthrene

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12 December 2020

Phalloidin-induced hyperplasia of actin filaments in rat hepatocytes

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12 December 2020

Up-regulation of P-glycoprotein expression in rat liver cells by acute doxorubicin treatment

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12 December 2020

Bile as a source of potential reactive metabolites

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12 December 2020

Functional impairment of sinusoidal membrane transport of organic cations in rats with CCl4-induced hepatic failure

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12 December 2020

The kinetics of mycophenolic acid and its glucuronide metabolite in adult kidney transplant recipients

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12 December 2020

Hepatic organic anion uptake in the rat

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12 December 2020

Induction of sodium-dependent bile acid transporter messenger RNA, protein, and activity in rat ileum by cholic acid

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12 December 2020

Perfused rat intrahepatic bile ducts secrete and absorb water, solute, and ions

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12 December 2020

Pharmacology of irinotecan

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12 December 2020

Absorption and disposition including enterohepatic circulation of (14C) roquinimex after oral administration to healthy volunteers

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12 December 2020

Solute and water transport pathways in cholangiocytes

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12 December 2020

Hexadecane enhances non-biliary, intestinal excretion of stored hexachlorobenzene by rats

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12 December 2020

Intracellular transport of small hydrophobic compounds by the hepatocyte

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12 December 2020

Transfer of enalaprilat across rat liver cell membranes is barrier limited

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12 December 2020

Clinical pharmacokinetics of contraceptive steroids. An update

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12 December 2020

Bimolecular glutathione conjugation kinetics of ethacrynic acid in rat liver: in vitro and perfusion studies

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12 December 2020

The identity of glutathione S-transferase B with ligandin, a major binding protein of liver

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12 December 2020

Genetic defects in hepatocanalicular transport.

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12 December 2020

Biliary excretion and enterohepatic circulation of paracetamol in the rat

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12 December 2020

The transport of bile acids in liver cells

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12 December 2020

Decreased uptake of taurocholate and ouabain by hepatocytes isolated from cirrhotic rat liver

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12 December 2020

Bilirubin. Solubility and interaction with albumin and phospholipid

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12 December 2020

ATP-dependent transport of bile salts by rat multidrug resistance-associated protein 3 (Mrp3)

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12 December 2020

Different capacities for amino acid transport in periportal and perivenous hepatocytes isolated by digitonin/collagenase perfusion

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12 December 2020

Localization of cytochrome P-450 gene expression in normal and diseased human liver by in situ hybridization of wax-embedded archival material.

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12 December 2020

Sex differences in intracellular fatty acid transport: role of cytoplasmic binding proteins

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12 December 2020

Bile flow decrease and altered bile composition in streptozotocin-treated rats

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12 December 2020

Choosing the right nonsteroidal anti-inflammatory drug for the right patient: a pharmacokinetic approach

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12 December 2020

The function of alkaline phosphatase in the liver: regulation of intrahepatic biliary epithelium secretory activities in the rat

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12 December 2020

The ductular cell reaction of rat liver in extrahepatic cholestasis. I. Proliferated biliary epithelial cells

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12 December 2020

Excretion of lead in rat bile--the role of glutathione

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12 December 2020

Accumulation and time to steady state for drugs subject to enterohepatic cycling: a stimulation study

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12 December 2020

Membrane transport in hepatic clearance of drugs. II: Zonal distribution patterns of concentration-dependent transport and elimination processes

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12 December 2020

Intrahepatic cholestasis induced by drugs and chemicals

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12 December 2020

Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver.

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12 December 2020

Voltage-driven, taurocholate-dependent secretion in isolated hepatocyte couplets

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12 December 2020

Hepatocellular uptake of sulfobromophthalein and bilirubin is selectively inhibited by an antibody to the liver plasma membrane sulfobromophthalein/bilirubin binding protein

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12 December 2020

Quantitative and temporal delineation of various parameters of liver dysfunction due to α-naphthylisothiocyanate

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12 December 2020

Expression and regulation of hepatic drug and bile acid transporters

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12 December 2020

The incidence of cholelithiasis, cholesterosis, and liver disease in diabetes mellitus: an autopsy study

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12 December 2020

Hepatic bile acid transport: effect of conjugation and position of hydroxyl groups

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12 December 2020

The intralobular distribution of ethanol-inducible P450IIE1 in rat and human liver

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12 December 2020

Zonal distribution of cysteine uptake in the perfused rat liver

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12 December 2020

Diabetes-induced alterations in liver protein synthesis. Changes in the relative abundance of mRNAs for albumin and other plasma proteins

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12 December 2020

Pharmacokinetics of ceftazidime in patients with biliary tract disease.

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12 December 2020

Hepatobiliary elimination of trovafloxacin and metabolites following single oral doses in healthy volunteers.

1 reference

12 December 2020

Effect of ursodeoxycholate on the bile flow in the rat

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12 December 2020

Clinical pharmacokinetics of tricyclic antidepressant overdose

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12 December 2020

Quantitative aspects of the interaction of bile acids with human serum albumin.

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12 December 2020

A double-peak phenomenon in the pharmacokinetics of alprazolam after oral administration.

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12 December 2020

Interindividual variability in inhibition and induction of cytochrome P450 enzymes

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12 December 2020

Uptake of imipramine in rat liver lysosomes in vitro and its inhibition by basic drugs

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12 December 2020

Cytochrome P450 3A: ontogeny and drug disposition

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12 December 2020

A human physiologically-based model for glycyrrhzic acid, a compound subject to presystemic metabolism and enterohepatic cycling.

1 reference

12 December 2020

Primary active transport of organic anions on bile canalicular membrane in humans

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12 December 2020

Ceftriaxone. A reappraisal of its antibacterial activity and pharmacokinetic properties, and an update on its therapeutic use with particular reference to once-daily administration

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12 December 2020

Commentary: using the convection-dispersion model and transit time density functions in the analysis of organ distribution kinetics.

1 reference

12 December 2020

Enterohepatic Cycling and Pharmacokinetics of Oestradiol in Postmenopausal Women

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12 December 2020

Transport of drugs across the hepatic sinusoidal membrane: sinusoidal drug influx and efflux in the liver

1 reference

12 December 2020

Cholestyramine: use as a new therapeutic approach for chlordecone (kepone) poisoning

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12 December 2020

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12 December 2020

Enterohepatic circulation model for population pharmacokinetic analysis

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12 December 2020

Diclofenac acyl glucuronide, a major biliary metabolite, is directly involved in small intestinal injury in rats

1 reference

12 December 2020

Growth hormone-regulated periportal expression of CYP2C7 in rat liver

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12 December 2020

Immunohistochemical distribution and functional characterization of an organic anion transporting polypeptide 2 (oatp2).

1 reference

12 December 2020

Ethacrynic acid and its glutathione conjugate as inhibitors of glutathione S-transferases

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12 December 2020

Pharmacokinetic study of the hepatobiliary transport of indomethacin

1 reference

12 December 2020

Effect of cholestyramine-induced bile acid depletion on the hepatobiliary transport of cholephilic organic anions in rats

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12 December 2020

Bilirubin Acidity. Titrimetric and 13C NMR Studies

1 reference

12 December 2020

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10.2165/00003088-200241100-00005

Identifiers

DOI

1 reference

Dimensions Publication ID

4 August 2017

0 references

1 reference