(Q41066462)

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18 October 2019

review article

1 reference

title

Clinical pharmacokinetics of therapeutic bile acids (English)

1 reference

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18 October 2019

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5

1 reference

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18 October 2019

3

P Invernizzi

1 reference

18 October 2019

A Crosignani

1

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18 October 2019

K D Setchell

series ordinal

2

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18 October 2019

A Larghi

series ordinal

4

1 reference

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18 October 2019

M Podda

series ordinal

6

1 reference

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18 October 2019

publication date

1 May 1996

1 reference

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Clinical Pharmacokinetics

18 October 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8743334%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

volume

30

1 reference

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18 October 2019

issue

5

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18 October 2019

page(s)

333-358

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Effect of taurine supplementation on fat and bile acid absorption in patients with cystic fibrosis

18 October 2019

cites work

1 reference

12 December 2020

Bioavailability study of a new, sinking, enteric-coated ursodeoxycholic acid formulation

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Tauroursodeoxycholic acid for treatment of primary biliary cirrhosis. A dose-response study

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12 December 2020

Determination of cholic acid and chenodeoxycholic acid pool sizes and fractional turnover rates by means of stable isotope dilution technique, making use of deuterated cholic acid and chenodeoxycholic acid

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12 December 2020

A physiological method for estimation of hepatic secretion of biliary lipids in man

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12 December 2020

Hepatoprotection by hydrophilic bile salts

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12 December 2020

Metabolism of bile acids. I. Absorption, distribution, excretion, and metabolism of ursodeoxycholic acid

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Conjugated and unconjugated serum bile acid levels n patients with hepatobiliary diseases

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12 December 2020

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12 December 2020

Bile acid N-acetylglucosaminidation. In vivo and in vitro evidence for a selective conjugation reaction of 7 beta-hydroxylated bile acids in humans

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12 December 2020

Metabolism of bile acids. IV. Absorption, distribution, excretion and metabolism of orally administered ursodeoxycholic acid in rats

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12 December 2020

Changes in biliary lipid and biliary bile acid composition in patients after administration of ursodeoxycholic acid

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Enterohepatic circulation in man. A simple method for the determination of duodenal bile acids.

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12 December 2020

Taurocholate transport by rat liver sinusoidal membrane vesicles: evidence of sodium cotransport

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12 December 2020

Bile acid glycine and taurine conjugates in serum of patients with primary biliary cirrhosis: effect of ursodeoxycholic treatment

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Cholic acid synthesis as an index of the severity of liver disease in man.

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Hepatic transport of bile acids in the isolated perfused rat liver. Structure-kinetic relationship

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12 December 2020

Intestinal absorption of ursodeoxycholic acid in patients with extrahepatic biliary obstruction and bile drainage

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12 December 2020

Sulphated and unsulphated bile acids in serum, bile, and urine of patients with cholestasis

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12 December 2020

Transport, metabolism, and effect of chronic feeding of cholylsarcosine, a conjugated bile acid resistant to deconjugation and dehydroxylation

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12 December 2020

Bile acids and their sulphated and glucuronidated derivatives in bile, plasma, and urine of children with intrahepatic cholestasis: effects of phenobarbital treatment

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12 December 2020

Molecular aspects of membrane stabilization by ursodeoxycholate [see comment]

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12 December 2020

Effect of ursodeoxycholic acid administration on biliary lipid secretion in primary biliary cirrhosis

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12 December 2020

Diurnal changes in serum unconjugated bile acids in normal man.

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12 December 2020

Identification of unconjugated bile acids in human bile

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12 December 2020

Effects of ursodeoxycholic acid therapy for liver disease associated with cystic fibrosis

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12 December 2020

Ileal excretion of bile acids: Comparison with biliary bile composition and effect of ursodeoxycholic acid treatment

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12 December 2020

Biliary lipid output during three meals and an overnight fast. I. Relationship to bile acid pool size and cholesterol saturation of bile in gallstone and control subjects

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12 December 2020

Effect of ursodeoxycholic acid administration on biliary lipid composition and bile acid kinetics in cholesterol gallstone patients

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12 December 2020

.DELTA.22-Ursodeoxycholic Acid, a Unique Metabolite of Administered Ursodeoxycholic Acid in Rats, Indicating Partial .beta.-Oxidation as a Major Pathway for Bile Acid Metabolism

1 reference

12 December 2020

Increased concentrations of cholestanol and apolipoprotein B in the cerebrospinal fluid of patients with cerebrotendinous xanthomatosis. Effect of chenodeoxycholic acid

1 reference

12 December 2020

Acute effects of ursodeoxycholic and chenodeoxycholic acid on the small intestinal absorption of bile acids

1 reference

12 December 2020

Effect of Oral Chenodeoxycholic Acid on Bile Acid Kinetics and Biliary Lipid Composition in Women with Cholelithiasis

1 reference

12 December 2020

Transformation of chenodeoxycholic acid and ursodeoxycholic acid by human intestinal bacteria

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12 December 2020

Biliary lipid synthesis and secretion in gallstone patients before and during treatment with chenodeoxycholic acid

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12 December 2020

Effects of ursodeoxycholic acid and taurine on serum liver enzymes and bile acids in chronic hepatitis

1 reference

12 December 2020

Chemistry and enterohepatic circulation of bile acids

1 reference

12 December 2020

pH-Solubility relations of chenodeoxycholic and ursodeoxycholic acids: physical-chemical basis for dissimilar solution and membrane phenomena

1 reference

12 December 2020

Effects of tauroursodeoxycholic acid on cytosolic Ca2+ signals in isolated rat hepatocytes

1 reference

12 December 2020

Hepatic cholesterol and bile acid metabolism in subjects with gallstones: comparative effects of short erm feeding of chenodeoxycholic and ursodeoxycholic acid

1 reference

12 December 2020

Comparative effects of ursodeoxycholic acid and chenodeoxycholic acid on bile acid kinetics and biliary lipid secretion in humans. Evidence for different modes of action on bile acid synthesis.

1 reference

12 December 2020

Comprehensive study of the biliary bile acid composition of patients with cystic fibrosis and associated liver disease before and after UDCA administration

1 reference

12 December 2020

Effect of ursodeoxycholic acid on bile acid metabolism in primary biliary cirrhosis.

1 reference

12 December 2020

Efficacy and safety of a combination of chenodeoxycholic acid and ursodeoxycholic acid for gallstone dissolution: a comparison with ursodeoxycholic acid alone

1 reference

12 December 2020

Hepatobiliary disease in cystic fibrosis: a survey of current issues and concepts

1 reference

12 December 2020

Effect of taurine supplements on fat absorption in cystic fibrosis.

1 reference

12 December 2020

Physicochemical and physiological properties of cholylsarcosine. A potential replacement detergent for bile acid deficiency states in the small intestine

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12 December 2020

Uptake of Taurocholic Acid into Isolated Rat-Liver Cells

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12 December 2020

Pharmacology of chenodeoxycholic acid. I. Pharmaceutical properties

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12 December 2020

Effect of long-term treatment with ursodiol on clinical and biochemical features and biliary bile acid metabolism in patients with primary biliary cirrhosis

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12 December 2020

Ursodeoxycholic acid in the treatment of cholesterol cholelithiasis. part I

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12 December 2020

Ursodiol for the long-term treatment of primary biliary cirrhosis. The UDCA-PBC Study Group.

1 reference

12 December 2020

Tauroursodeoxycholate increases rat liver ursodeoxycholate levels and limits lithocholate formation better than ursodeoxycholate

1 reference

12 December 2020

A pharmacokinetic analysis of enterohepatic circulation of ursodeoxycholic acid, a drug with a high hepatic extraction but a small clearance.

1 reference

12 December 2020

Dietary glycine and taurine on bile acid conjugation in man; bile acids and steroids 75

1 reference

12 December 2020

Ursodeoxycholic acid administration on bile acid metabolism in patients with early stages of primary biliary cirrhosis

1 reference

12 December 2020

Dissolution of cholesterol gallstones by long-term administration of ursodeoxycholic acid

1 reference

12 December 2020

Identification and quantitative determination of urinary bile acids excreted in cholestasis

1 reference

12 December 2020

Biliary and urinary excretion of sulfated, glucuronidated and tetrahydroxylated bile acids in cirrhotic patients

1 reference

12 December 2020

Ursodeoxycholic acid in chronic liver disease

1 reference

12 December 2020

Effect of ursodeoxycholic acid on the kinetics of cholic acid and chenodeoxycholic acid in patients with primary sclerosing cholangitis

1 reference

12 December 2020

Ursodeoxycholic acid in the treatment of cholesterol cholelithiasis. Part II.

1 reference

12 December 2020

Side chain conjugation prevents bacterial 7-dehydroxylation of bile acids

1 reference

12 December 2020

Characterization of serum and urinary bile acids in patients with primary biliary cirrhosis by gas-liquid chromatography-mass spectrometry: effect of ursodeoxycholic acid treatment

1 reference

12 December 2020

Metabolism of bile acids. V . Metabolism of ursodeoxycholic acid in rhesus monkey

1 reference

12 December 2020

Difference in the effects of ursodeoxycholate and its taurine conjugate on the biliary excretion of sulfobromophthalein in the rat.

1 reference

12 December 2020

Ursodeoxycholic acid therapy: the baby and the bathwater

1 reference

12 December 2020

Bile acid metabolism in cirrhotic liver tissue--altered synthesis and impaired hepatic secretion

1 reference

12 December 2020

Effect of high and low doses of ursodeoxycholic acid on gallstone dissolution in humans

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12 December 2020

Bile acid profiles of human serum and skin interstitial fluid and their relationship to pruritus studied by gas chromatography-mass spectrometry

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12 December 2020

The turnover of cholic acid in man: bile acids and steroids

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12 December 2020

Ursodeoxycholic acid for chronic liver diseases

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12 December 2020

Bile secretory characteristics of beta-muricholate and its taurine conjugate are similar to those of ursodeoxycholate in the rat

1 reference

12 December 2020

Immunomodulatory effects of ursodeoxycholic acid on immune responses

1 reference

12 December 2020

Formation, absorption, and biotransformation of delta 6-lithocholenic acid in humans

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12 December 2020

Ursodiol for hepatobiliary disorders

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12 December 2020

Ursodeoxycholic acid therapy in cystic fibrosis-associated liver disease: a dose-response study.

1 reference

12 December 2020

Ursodeoxycholic acid: a review of its pharmacological properties and therapeutic efficacy

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12 December 2020

Direct determination of the driving forces for taurocholate uptake into rat liver plasma membrane vesicles

1 reference

12 December 2020

Cystic fibrosis in adults. 75 cases and a review of 232 cases in the literature

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12 December 2020

The site-specific delivery of ursodeoxycholic acid to the rat colon by sulfate conjugation.

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12 December 2020

Biliary lipid secretion in chronic cholestatic liver disease

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12 December 2020

Oral bile acids in cystic fibrosis-associated liver disease

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12 December 2020

Mechanisms for reduced hepatic clearance and elevated plasma levels of bile acids in cirrhosis. A study in patients with an end-to-side portacaval shunt

1 reference

12 December 2020

Formation of delta 22-bile acids in rats is not gender specific and occurs in the peroxisome.

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12 December 2020

Pharmacology of ursodeoxycholic acid, an enterohepatic drug.

1 reference

12 December 2020

Metabolism of ursodeoxycholic acid in man

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12 December 2020

Metabolism of lethocholate in healthy man. I. Biotransformation and biliary excretion of intravenously administered lithocholate, lithocholylglycine, and their sulfates

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12 December 2020

Serum bile acid analysis

1 reference

12 December 2020

Degradation of steroids by intestinal bacteria. II. Enzymes catalysing the oxidoreduction of the 3 alpha-, 7 alpha- and 12 alpha-hydroxyl groups in cholic acid, and the dehydroxylation of the 7-hydroxyl group.

1 reference

12 December 2020

Conjugation is rate limiting in hepatic transport of ursodeoxycholate in the rat

1 reference

12 December 2020

Tauro alpha-muricholate is as effective as tauro beta-muricholate and tauroursodeoxycholate in preventing taurochenodeoxycholate-induced liver damage in the rat

1 reference

12 December 2020

BILE ACIDS. XIX. METABOLISM OF LITHOCHOLIC ACID-24-14C IN THE RAT

1 reference

12 December 2020

Metabolism of bile acids. VII. Metabolism of ursodeoxycholic acid in female rats

1 reference

12 December 2020

Ursodeoxycholic acid ingestion after ileal resection. Effect on biliary bile acid and lipid composition.

1 reference

12 December 2020

Physicochemical properties of bile acids and their relationship to biological properties: an overview of the problem

1 reference

12 December 2020

Comparative studies of metabolism of simultaneously administered chenodeoxycholic acid and ursodeoxycholic acid in hamsters

1 reference

12 December 2020

Pool size, synthesis, and turnover of sulfated and nonsulfated cholic acid and chenodeoxycholic acid in patients with cirrhosis of the liver

1 reference

12 December 2020

Kinetics of hepatic bile acid handling in cholestatic liver disease: effect of ursodeoxycholic acid.

1 reference

12 December 2020

Gallstone dissolution with ursodeoxycholic acid in patients with chronic active hepatitis and two years follow-up. A pilot study

1 reference

12 December 2020

Effect of ursodeoxycholic acid and chenodeoxycholic acid on cholesterol and bile acid metabolism.

1 reference

12 December 2020

Effect of different doses of ursodeoxycholic acid in chronic liver disease

1 reference

12 December 2020

Biliary lipid output during three meals and an overnight fast. II. Effect of chenodeoxycholic acid treatment in gallstone subjects

1 reference

12 December 2020

Malabsorption of Bile Acids in Children with Cystic Fibrosis

1 reference

12 December 2020

Metabolism in man of 7-ketolithocholic acid: precursor of cheno- and ursodeoxycholic acids

1 reference

12 December 2020

Serum bile acids in primary biliary cirrhosis: effect of ursodeoxycholic acid therapy

1 reference

12 December 2020

Dissolution of Cholesterol Gallstones by Chenodeoxycholic Acid

1 reference

12 December 2020

Ursodeoxycholic acid inhibits glucagon-induced cAMP formation in hamster hepatocytes: a role for PKC

1 reference

12 December 2020

Effects of controlled interruption of the enterohepatic circulation of bile salts by biliary diversion and by ileal resection on bile salt secretion, synthesis, and pool size in the rhesus monkey

1 reference

12 December 2020

Effect of ursodeoxycholate on the bile flow in the rat

1 reference

12 December 2020

Ursodeoxycholic acid for primary biliary cirrhosis

1 reference

12 December 2020

Quantitative aspects of the interaction of bile acids with human serum albumin.

1 reference

12 December 2020

Absorption of urso- and chenodeoxycholic acid and their taurine and glycine conjugates in rat jejunum, ileum, and colon.

1 reference

12 December 2020

Metabolism of orally administered tauroursodeoxycholic acid in patients with primary biliary cirrhosis.

1 reference

12 December 2020

Chenodiol (chenodeoxycholic acid) for dissolution of gallstones: the National Cooperative Gallstone Study. A controlled trial of efficacy and safety

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12 December 2020

Postprandial concentrations of free and conjugated bile acids down the length of the normal human small intestine

1 reference

12 December 2020

Intestinal absorption of ursodeoxycholic, glycoursodeoxycholic and tauroursodeoxycholic acids in rats

1 reference

12 December 2020

The effect of tauroursodeoxycholic acid and taurine supplementation on biliary bile acid composition

1 reference

12 December 2020

Effect of ursodeoxycholic acid on the kinetics of the major hydrophobic bile acids in health and in chronic cholestatic liver disease

1 reference

12 December 2020

Sulfated and nonsulfated bile acids in urine, serum, and bile of patients with hepatobiliary diseases

1 reference

12 December 2020

Excessive Fecal Taurine Loss Predisposes to Taurine Deficiency in Cystic Fibrosis

1 reference

12 December 2020

Pharmacology of chenodeoxycholic acid. II. Absorption and metabolism

1 reference

12 December 2020

Ursodeoxycholic acid-induced changes of plasma and urinary bile acids in patients with primary biliary cirrhosis

1 reference

12 December 2020

Uptake of bile acids by perfused rat liver: evidence of a structure-activity relationship

1 reference

12 December 2020

Ursodeoxycholate protects oxidative mitochondrial metabolism from bile acid toxicity: dose-response study in isolated rat liver mitochondria

1 reference

12 December 2020

Effect of Na on bile acid uptake by isolated rat hepatocytes. Evidence for a heterogeneous system

1 reference

12 December 2020

Analysis of metabolic profiles of bile acids in urine using a lipophilic anion exchanger and computerized gas-liquid chromatorgaphy-mass spectrometry

1 reference

12 December 2020

Differing effects of ursodeoxycholic or chenodeoxycholic acid on biliary cholesterol saturation and bile acid metabolism in man. A dose-response study

1 reference

12 December 2020

Evaluation of an oral ursodeoxycholic acid load in the assessment of bile acid malabsorption in cystic fibrosis.

1 reference

12 December 2020

Changes in bile acid composition in patients with primary biliary cirrhosis induced by ursodeoxycholic acid administration

1 reference

12 December 2020