(Q35669295)

9 August 2017

A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis (English)

1 reference

focal segmental glomerulosclerosis

9 August 2017

1 reference

1 reference

Harm Peters

6

0 references

Howard Trachtman

object named as

Howard Trachtman

1

0 references

Giuseppe Remuzzi

object named as

Giuseppe Remuzzi

8

0 references

Debbie S Gipson

3

object named as

Debbie S Gipson

1 reference

9 August 2017

Fernando C Fervenza

2

1 reference

9 August 2017

Peter Heering

4

1 reference

9 August 2017

David R W Jayne

5

1 reference

9 August 2017

Stefano Rota

7

1 reference

9 August 2017

L Christian Rump

9

1 reference

9 August 2017

Lorenz K Sellin

10

1 reference

9 August 2017

Jeremy P W Heaton

11

1 reference

9 August 2017

James B Streisand

12

1 reference

9 August 2017

Marjie L Hard

13

1 reference

9 August 2017

Steven R Ledbetter

14

1 reference

9 August 2017

Flavio Vincenti

15

1 reference

9 August 2017

language of work or name

English

0 references

publication date

2 March 2011

1 reference

9 August 2017

1 reference

9 August 2017

79

1 reference

9 August 2017

1236-1243

1 reference

9 August 2017

11

1 reference

https://scigraph.springernature.com/pub.10.1038/ki.2011.33

9 August 2017

0 references

cites work

Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Effects of TGF-beta on podocyte growth and disease progression in proliferative podocytopathies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Narrative review: fibrotic diseases: cellular and molecular mechanisms and novel therapies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Pharmacokinetics and pharmacodynamics of monoclonal antibodies: concepts and lessons for drug development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

PKC-alpha modulates TGF-beta signaling and impairs podocyte survival

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Rituximab treatment of adult patients with steroid-resistant focal segmental glomerulosclerosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Advances in the biology and genetics of the podocytopathies: implications for diagnosis and therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Therapeutic potential of TGF-beta inhibition in chronic renal failure

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Focal segmental glomerulosclerosis--epidemiology aspects in children and adults

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Therapeutic approach to FSGS in children

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Treatment and outcome of adult patients with primary focal segmental glomerulosclerosis in five UK renal units

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Focal and segmental glomerulosclerosis: definition and relevance of a partial remission

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Mycophenolate mofetil in the treatment of focal segmental glomerulosclerosis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Cyclosporine A and chlorambucil in the treatment of idiopathic focal segmental glomerulosclerosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Activation of the TGF-beta/Smad signaling pathway in focal segmental glomerulosclerosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Focal segmental glomerulosclerosis in adults.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Mycophenolate mofetil treatment for primary glomerular diseases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Apoptosis in podocytes induced by TGF-beta and Smad7

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease. A meta-analysis of patient-level data

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Renoprotection: one or many therapies?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Primary focal segmental glomerulosclerosis: clinical course, predictors of renal outcome and treatment

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

A randomized trial of cyclosporine in patients with steroid-resistant focal segmental glomerulosclerosis. North America Nephrotic Syndrome Study Group.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Management of focal segmental glomerulosclerosis: evidence-based recommendations.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

A randomized trial of cyclosporine in steroid-resistant idiopathic nephrotic syndrome.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Angiotensin converting enzyme inhibitors for reduction of proteinuria in children with steroid-resistant nephrotic syndrome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Long-term outcome of children with steroid-resistant nephrotic syndrome treated with tacrolimus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

p35, the non-cyclin activator of Cdk5, protects podocytes against apoptosis in vitro and in vivo.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Tacrolimus therapy in adults with steroid- and cyclophosphamide-resistant nephrotic syndrome and normal or mildly reduced GFR.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

The Notch pathway in podocytes plays a role in the development of glomerular disease

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Transforming growth factor-beta, 20-HETE interaction, and glomerular injury in Dahl salt-sensitive rats

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Prevalence of WT1 mutations in a large cohort of patients with steroid-resistant and steroid-sensitive nephrotic syndrome.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Pathologic classification of focal segmental glomerulosclerosis: a working proposal

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Therapeutic role of TGF-beta-neutralizing antibody in mouse cyclosporin A nephropathy: morphologic improvement associated with functional preservation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Antiproteinuric effect of blood-pressure-lowering agents: a meta-analysis of comparative trials.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Beneficial effect of TGFbeta antagonism in treating diabetic nephropathy depends on when treatment is started

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Sirolimus Therapy of Focal Segmental Glomerulosclerosis Is Associated With Nephrotoxicity

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257033

Idiopathic membranous nephropathy: definition and relevance of a partial remission

15 November 2018

1 reference

12 December 2020

Blood pressure control, proteinuria, and the progression of renal disease. The Modification of Diet in Renal Disease Study

1 reference

12 December 2020

A randomized double-blind placebo-controlled trial of cyclosporine in steroid-resistant idiopathic focal segmental glomerulosclerosis in children

1 reference

12 December 2020

Long-term therapy with enalapril in patients with nephrotic-range proteinuria

1 reference

12 December 2020

ACE-inhibitors: panacea for progressive renal disease

1 reference

12 December 2020

Are angiotensin converting enzyme inhibitors superior to beta blockers in retarding progressive renal function decline?

1 reference

12 December 2020

Successful mycophenolate mofetil treatment of glomerular disease

1 reference

12 December 2020

Angiotensin converting enzyme inhibitors and angiotensin receptor (AT1) antagonists: either or both for primary renal disease

1 reference

12 December 2020

Glomerular epithelial cells transform to myofibroblasts: early but not late removal of TGF-beta1 reverses transformation

1 reference

12 December 2020

Specific changes in plasma concentrations of matrix metalloproteinase-2 and -9, TIMP-1 and TGF- 1 in patients with distinct types of primary glomerulonephritis

1 reference

12 December 2020

Identifiers

DOI

10.1038/KI.2011.33

1 reference

Dimensions Publication ID

9 August 2017

0 references

1 reference

9 August 2017

1 reference