(Q35671629)

9 August 2017

1 reference

27 November 2019

The role of C5a in acute lung injury induced by highly pathogenic viral infections (English)

1 reference

9 August 2017

viral infectious disease

1 reference

27 November 2019

1 reference

3 November 2019

complement component 5a

1 reference

27 November 2019

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060601%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

3

Renfeng Guo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060601%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

5

Beifen Shen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060601%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

He Xiao

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060601%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Yan Li

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060601%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

1 reference

6 May 2015

1 reference

PubMed ID

26060601

Emerging Microbes & Infections

9 August 2017

1 May 2015

3 references

23 March 2019

3 November 2019

27 November 2019

4 references

23 March 2019

3 November 2019

27 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060601%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060601%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060601%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

e28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060601%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International

13 June 2020

copyright license

3 references

23 March 2019

3 November 2019

on focus list of Wikimedia project

27 November 2019

ScienceSource

0 references

cites work

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12 July 2018

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Treatment with anti-C5a antibody improves the outcome of H7N9 virus infection in African green monkeys

12 July 2018

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Oxidative stress and free radicals in COPD--implications and relevance for treatment

12 July 2018

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Clinical features and pathobiology of Ebolavirus infection

12 July 2018

1 reference

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Human H7N9 and H5N1 influenza viruses differ in induction of cytokines and tissue tropism.

12 July 2018

1 reference

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Histone deacetylase 6 inhibits influenza A virus release by downregulating the trafficking of viral components to the plasma membrane via its substrate, acetylated microtubules

12 July 2018

1 reference

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Profiles of acute cytokine and antibody responses in patients infected with avian influenza A H7N9

12 July 2018

1 reference

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Complement system in lung disease

12 July 2018

1 reference

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Dynamic behavior of lymphocyte subgroups correlates with clinical outcomes in human H7N9 infection

12 July 2018

1 reference

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Critical role for the NLRP3 inflammasome during acute lung injury

12 July 2018

1 reference

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Protein-based therapies for acute lung injury: targeting neutrophil extracellular traps

12 July 2018

1 reference

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Severe H7N9 infection is associated with decreased antigen-presenting capacity of CD14+ cells.

12 July 2018

1 reference

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Inhibition of the inflammatory cytokine tumor necrosis factor-alpha with etanercept provides protection against lethal H1N1 influenza infection in mice

12 July 2018

1 reference

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Middle East Respiratory Syndrome-coronavirus infection: an overview

12 July 2018

1 reference

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Extracellular histones are essential effectors of C5aR- and C5L2-mediated tissue damage and inflammation in acute lung injury

12 July 2018

1 reference

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The Middle East respiratory syndrome--how worried should we be?

12 July 2018

1 reference

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Clinical, virological, and histopathological manifestations of fatal human infections by avian influenza A(H7N9) virus

12 July 2018

1 reference

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Viral pathogens and acute lung injury: investigations inspired by the SARS epidemic and the 2009 H1N1 influenza pandemic

12 July 2018

1 reference

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Antiviral and anti-inflammatory activity of arbidol hydrochloride in influenza A (H1N1) virus infection

12 July 2018

1 reference

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Interspecies transmission and emergence of novel viruses: lessons from bats and birds

12 July 2018

1 reference

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Complement C5 activation during influenza A infection in mice contributes to neutrophil recruitment and lung injury

12 July 2018

1 reference

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Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells

12 July 2018

1 reference

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Extraordinary GU-rich single-strand RNA identified from SARS coronavirus contributes an excessive innate immune response.

12 July 2018

1 reference

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Impaired secretion of interferons by dendritic cells from aged subjects to influenza : role of histone modifications

12 July 2018

1 reference

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Neutrophil extracellular traps: is immunity the second function of chromatin?

12 July 2018

1 reference

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Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones

12 July 2018

1 reference

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Cofactor regulation of C5a chemotactic activity in physiological fluids. Requirement for the vitamin D binding protein, thrombospondin-1 and its receptors

12 July 2018

1 reference

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Excessive innate immune response and mutant D222G/N in severe A (H1N1) pandemic influenza

12 July 2018

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Excessive neutrophils and neutrophil extracellular traps contribute to acute lung injury of influenza pneumonitis

12 July 2018

1 reference

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A protective role for complement C3 protein during pandemic 2009 H1N1 and H5N1 influenza A virus infection

12 July 2018

1 reference

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Distinct severe acute respiratory syndrome coronavirus-induced acute lung injury pathways in two different nonhuman primate species

12 July 2018

1 reference

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Complement and viral pathogenesis

12 July 2018

1 reference

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Mice lacking both TNF and IL-1 receptors exhibit reduced lung inflammation and delay in onset of death following infection with a highly virulent H5N1 virus

12 July 2018

1 reference

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Alternative Complement Pathway Deregulation Is Correlated with Dengue Severity

12 July 2018

1 reference

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Attenuation of IgG immune complex-induced acute lung injury by silencing C5aR in lung epithelial cells

12 July 2018

1 reference

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The biology of influenza viruses

12 July 2018

1 reference

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Severe acute respiratory syndrome (SARS) coronavirus-induced lung epithelial cytokines exacerbate SARS pathogenesis by modulating intrinsic functions of monocyte-derived macrophages and dendritic cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

The cytokine network in asthma and chronic obstructive pulmonary disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells

12 July 2018

1 reference

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Confronting potential influenza A (H5N1) pandemic with better vaccines

12 July 2018

1 reference

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Role of host cytokine responses in the pathogenesis of avian H5N1 influenza viruses in mice

12 July 2018

1 reference

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Complement inhibitors selectively attenuate injury following administration of cobra venom factor to rats

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Mechanisms of cell death induced by the neutrophil antimicrobial peptides alpha-defensins and LL-37.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

The comparative pathology of severe acute respiratory syndrome and avian influenza A subtype H5N1--a review

12 July 2018

1 reference

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H5N1 Virus Attachment to Lower Respiratory Tract

12 July 2018

1 reference

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Avian flu: influenza virus receptors in the human airway

12 July 2018

1 reference

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Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells

12 July 2018

1 reference

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Gene expression profiles in peripheral blood mononuclear cells of SARS patients

12 July 2018

1 reference

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Persistence of lung inflammation and lung cytokines with high-resolution CT abnormalities during recovery from SARS

12 July 2018

1 reference

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Preparing for the next pandemic

12 July 2018

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Role of C5a in inflammatory responses

12 July 2018

1 reference

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Human disease from influenza A (H5N1), Thailand, 2004.

12 July 2018

1 reference

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An interferon-gamma-related cytokine storm in SARS patients

12 July 2018

1 reference

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Avian influenza A (H5N1) in 10 patients in Vietnam

12 July 2018

1 reference

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Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome

12 July 2018

1 reference

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Mediators and regulation of neutrophil accumulation in inflammatory responses in lung: insights from the IgG immune complex model

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Neutrophils in chronic obstructive pulmonary disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

rC5a directs the in vitro migration of human memory and naive tonsillar B lymphocytes: implications for B cell trafficking in secondary lymphoid tissues

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Human T cells express the C5a receptor and are chemoattracted to C5a.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Role of complement, chemokines, and regulatory cytokines in acute lung injury

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Synergistic transcriptional activation of the IL-8 gene by NF-kappa B p65 (RelA) and NF-IL-6.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Immunocomplexes stimulate different signalling events to chemoattractants in the neutrophil and regulate L-selectin and beta 2-integrin expression differently

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Adult respiratory distress syndrome--I. Aetiology and mechanisms

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Neutrophils and the adult respiratory distress syndrome.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Pulmonary alveolar type II epithelial cells synthesize and secrete proteins of the classical and alternative complement pathways

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Dependence on O2- generation by xanthine oxidase of pathogenesis of influenza virus infection in mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Complement is activated in the upper respiratory tract during influenza virus infection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Cytokine-induced neutrophil-derived interleukin-8.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Complement (C5-a)-induced granulocyte aggregation in vitro. A possible mechanism of complement-mediated leukostasis and leukopenia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Oxygen radicals mediate endothelial cell damage by complement-stimulated granulocytes. An in vitro model of immune vascular damage

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Editorial commentary: New strategies for treatment of humans with acute lung injury/acute respiratory distress syndrome.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

H5N1 infection causes rapid mortality and high cytokine levels in chickens compared to ducks.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

The emergence of influenza A H7N9 in human beings 16 years after influenza A H5N1: a tale of two cities

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Inhibition of complement activation alleviates acute lung injury induced by highly pathogenic avian influenza H5N1 virus infection

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

NET balancing: a problem in inflammatory lung diseases

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Doxycycline treatment attenuates acute lung injury in mice infected with virulent influenza H3N2 virus: involvement of matrix metalloproteinases

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Role of macrophage migration inhibitory factor in influenza H5N1 virus pneumonia.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

[A study of pulmonary inflammatory reaction induced by N-protein of SARS-CoV in rat models and effects of glucocorticoids on it].

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Chemokine up-regulation in SARS-coronavirus-infected, monocyte-derived human dendritic cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Complement C5a receptor is essential for the optimal generation of antiviral CD8+ T cell responses

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Complement factors c3a, c4a, and c5a in chronic obstructive pulmonary disease and asthma.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Inhibition of C5a-induced inflammation with preserved C5b-9-mediated bactericidal activity in a human whole blood model of meningococcal sepsis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Role of C5a in multiorgan failure during sepsis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Inhibition of interleukin-6 synthesis in an animal model of septic shock by anti-C5a monoclonal antibodies

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

Influenza virus induces expression of antioxidant genes in human epithelial cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451266

25 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMI.2015.28

Regulation of IL-8 production by complement-activated product, C5a, in vitro and in vivo during sepsis

21 January 2018

1 reference

12 December 2020

C3a and C5a enhance granulocyte adhesion to endothelial and epithelial cell monolayers: epithelial and endothelial priming is required for C3a-induced eosinophil adhesion

1 reference

12 December 2020

Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines

1 reference

12 December 2020

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

1 reference

12 December 2020

Serum concentrations of complement anaphylatoxins and proinflammatory mediators in patients with 2009 H1N1 influenza

1 reference

12 December 2020

Differential regulation of responsiveness to fMLP and C5a upon dendritic cell maturation: correlation with receptor expression

1 reference

12 December 2020

Expression of elevated levels of pro-inflammatory cytokines in SARS-CoV-infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS

1 reference

12 December 2020

Psoriasis scales contain C5a as the predominant chemotaxin for monocyte-derived dendritic cells

1 reference

12 December 2020

Early local generation of C5a initiates the elicitation of contact sensitivity by leading to early T cell recruitment

1 reference

12 December 2020

Comparative effect of C3a and C5a on adhesion molecule expression on neutrophils and endothelial cells

1 reference

12 December 2020

Vascular endothelial cell expression of ICAM-1 and VCAM-1 at the onset of eliciting contact hypersensitivity in mice: evidence for a dominant role of TNF-alpha

1 reference

12 December 2020

Production of C2 by human alveolar macrophages

1 reference

12 December 2020

Complement biosynthesis by human bronchoalveolar macrophages

1 reference

12 December 2020

The complement component C3a fragment is a potential biomarker for hepatitis C virus-related hepatocellular carcinoma

1 reference

12 December 2020

Expression and modulation of C5a receptor (CD88) on skin dendritic cells. Chemotactic effect of C5a on skin migratory dendritic cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/EMI.2015.28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060601%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060601%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26060601%20AND%20SRC:MED&resulttype=core&format=json