(Q35673678)

9 August 2017

High metastatic potential in mice inheriting a targeted p53 missense mutation (English)

1 reference

Roberto Montes-de-Oca-Luna

9 August 2017

1 reference

3

object named as

Montes de Oca Luna R

1 reference

9 August 2017

Liu G

1

1 reference

9 August 2017

McDonnell TJ

2

1 reference

9 August 2017

Kapoor M

4

1 reference

9 August 2017

Mims B

5

1 reference

9 August 2017

El-Naggar AK

6

1 reference

9 August 2017

Lozano G

7

1 reference

9 August 2017

language of work or name

English

0 references

publication date

1 April 2000

1 reference

Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

1 reference

9 August 2017

97

1 reference

9 August 2017

4174-4179

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9 August 2017

8

1 reference

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

9 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

A transgenic mouse model for mammary carcinogenesis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

p53 is required for radiation-induced apoptosis in mouse thymocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

The transforming and suppressor functions of p53 alleles: effects of mutations that disrupt phosphorylation, oligomerization and nuclear translocation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

Double replacement: strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by homologous recombination in embryonic stem cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

Gain of function mutations in p53.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

Tumor spectrum analysis in p53-mutant mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

p53 increases experimental metastatic capacity of murine carcinoma cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

The p53 proto-oncogene can act as a suppressor of transformation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18187

Overproduction of p53 antigen makes established cells highly tumorigenic

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.97.8.4174

p53 point mutation and survival in colorectal cancer patients

21 January 2018

1 reference

12 December 2020

A test of the role of alpha5 integrin/fibronectin interactions in tumorigenesis

1 reference

12 December 2020

Exclusion of a p53 germline mutation in a classic Li-Fraumeni syndrome family

1 reference

12 December 2020

Loss of one but not two mdm2 null alleles alters the tumour spectrum in p53 null mice

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.97.8.4174

1 reference

release_y5syufzj6rhivgpnsvgqd3jece

9 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/y5syufzj6rhivgpnsvgqd3jece

24 November 2022

mapped directly with Wikidata item

PMCID

18187

1 reference

9 August 2017

1 reference