(Q35676502)

9 August 2017

title

Ecteinascidin-743: evidence of activity in advanced, pretreated soft tissue and bone sarcoma patients (English)

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9 August 2017

G Huygh

1

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9 August 2017

Paul M J Clement

2

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9 August 2017

H Dumez

3

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9 August 2017

P Schöffski

4

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9 August 2017

H Wildiers

5

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9 August 2017

J Selleslach

6

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9 August 2017

J M Jimeno

7

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9 August 2017

I De Wever

8

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9 August 2017

R Sciot

9

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9 August 2017

L Duck

10

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9 August 2017

A T Van Oosterom

11

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9 August 2017

publication date

31 December 2006

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9 August 2017

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9 August 2017

volume

2006

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9 August 2017

page(s)

56282

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Creative Commons Attribution 3.0 Unported

9 August 2017

copyright license

start time

1 January 2006

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Phase II study of ET-743 in advanced soft tissue sarcomas: a European Organisation for the Research and Treatment of Cancer (EORTC) soft tissue and bone sarcoma group trial

1 reference

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Phase II study of ecteinascidin-743 in advanced pretreated soft tissue sarcoma patients

27 July 2018

1 reference

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The use of chemotherapy in soft-tissue sarcomas

27 July 2018

1 reference

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Clinical pharmacology of the novel marine-derived anticancer agent Ecteinascidin 743 administered as a 1- and 3-h infusion in a phase I study

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820623

Sensitivity of soft tissue sarcoma cell lines to chemotherapeutic agents: identification of ecteinascidin-743 as a potent cytotoxic agent.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820623

Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820623

Phase I and pharmacokinetic study of ecteinascidin-743, a new marine compound, administered as a 24-hour continuous infusion in patients with solid tumors.

27 July 2018

1 reference

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Ecteinascidin-743: a marine-derived compound in advanced, pretreated sarcoma patients--preliminary evidence of activity

27 July 2018

1 reference

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Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743.

27 July 2018

1 reference

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27 July 2018

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High antitumour activity of ET743 against human tumour xenografts from melanoma, non-small-cell lung and ovarian cancer

27 July 2018

1 reference

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Prognostic factors for the outcome of chemotherapy in advanced soft tissue sarcoma: an analysis of 2,185 patients treated with anthracycline-containing first-line regimens--a European Organization for Research and Treatment of Cancer Soft Tissue and

27 July 2018

1 reference

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Ecteinascidin 743: a minor groove alkylator that bends DNA toward the major groove

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820623

In vitro antitumor activity of the novel marine agent, ecteinascidin-743 (ET-743, NSC-648766) against human tumors explanted from patients

27 July 2018

1 reference

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Phase II study of continuous-infusion high-dose ifosfamide in advanced and/or metastatic pretreated soft tissue sarcomas

27 July 2018

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DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata

27 July 2018

1 reference

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The present state of the art in chemotherapy for soft tissue sarcomas in adults: the EORTC point of view

27 July 2018

1 reference

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Response to ifosfamide and mesna: 124 previously treated patients with metastatic or unresectable sarcoma

27 July 2018

1 reference

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Results of randomised studies of the EORTC Soft Tissue and Bone Sarcoma Group (STBSG) with two different ifosfamide regimens in first- and second-line chemotherapy in advanced soft tissue sarcoma patients

27 July 2018

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Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation

21 January 2018

1 reference

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Differential cytostatic and apoptotic effects of ecteinascidin-743 in cancer cells. Transcription-dependent cell cycle arrest and transcription-independent JNK and mitochondrial mediated apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2FSRCM%2F2006%2F56282

Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2FSRCM%2F2006%2F56282

Current treatment of osteosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2FSRCM%2F2006%2F56282

A phase I and pharmacokinetic study of ecteinascidin-743 on a daily x 5 schedule in patients with solid malignancies

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820623

Phase I and pharmacokinetic study of ecteinascidin 743 administered as a 72-hour continuous intravenous infusion in patients with solid malignancies

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820623

Advanced soft-tissue sarcoma: a disease that is potentially curable for a subset of patients treated with chemotherapy

25 September 2018

1 reference

https://api.crossref.org/works/10.1155%2FSRCM%2F2006%2F56282

Effect of high-dose ifosfamide in advanced soft tissue sarcomas. A multicentre phase II study of the EORTC Soft Tissue and Bone Sarcoma Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2FSRCM%2F2006%2F56282

Randomized phase III study comparing conventional-dose doxorubicin plus ifosfamide versus high-dose doxorubicin plus ifosfamide plus recombinant human granulocyte-macrophage colony-stimulating factor in advanced soft tissue sarcomas: A trial of the

21 January 2018

1 reference

12 December 2020

Ecteinascidin-743, a new marine natural product with potent antitumor activity on human ovarian carcinoma xenografts

1 reference

12 December 2020

Cyclophosphamide versus ifosfamide: final report of a randomized phase II trial in adult soft tissue sarcomas

1 reference

12 December 2020

Analysis of prognostic factors in 1,041 patients with localized soft tissue sarcomas of the extremities

1 reference

12 December 2020

High-dose ifosfamide in bone and soft tissue sarcomas: results of phase II and pilot studies--dose-response and schedule dependence

1 reference

12 December 2020

Molecular and crystal structures of ecteinascidins: potent antitumor compounds from the Caribbean tunicate Ecteinascidia turbinata

1 reference

12 December 2020

Granulocyte-macrophage colony-stimulating factor allows safe escalation of dose-intensity of chemotherapy in metastatic adult soft tissue sarcomas: a study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcom

1 reference

12 December 2020

Progression-free rate as the principal end-point for phase II trials in soft-tissue sarcomas

1 reference

12 December 2020

Identifiers

DOI

10.1155/SRCM/2006/56282

1 reference

9 August 2017

1 reference

9 August 2017

1 reference