(Q35676802)

9 August 2017

title

Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase (English)

1 reference

9 August 2017

Mark G Manfredi

1

1 reference

9 August 2017

Jeffrey A Ecsedy

2

1 reference

9 August 2017

Kristan A Meetze

3

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9 August 2017

Suresh K Balani

4

1 reference

9 August 2017

Olga Burenkova

5

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9 August 2017

Wei Chen

6

1 reference

9 August 2017

Katherine M Galvin

7

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9 August 2017

Kara M Hoar

8

1 reference

9 August 2017

Jessica J Huck

9

1 reference

9 August 2017

Patrick J LeRoy

10

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9 August 2017

Emily T Ray

11

1 reference

9 August 2017

Todd B Sells

12

1 reference

9 August 2017

Bradley Stringer

13

1 reference

9 August 2017

Stephen G Stroud

14

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9 August 2017

Tricia J Vos

15

1 reference

9 August 2017

Gabriel S Weatherhead

16

1 reference

9 August 2017

Deborah R Wysong

17

1 reference

9 August 2017

Mengkun Zhang

18

1 reference

9 August 2017

Joseph B Bolen

19

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9 August 2017

Christopher F Claiborne

20

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9 August 2017

language of work or name

English

0 references

publication date

23 February 2007

1 reference

Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

published in

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9 August 2017

volume

104

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9 August 2017

issue

10

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9 August 2017

page(s)

4106-4111

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Aurora A, mitotic entry, and spindle bipolarity

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Discovery of novel and potent thiazoloquinazolines as selective Aurora A and B kinase inhibitors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Progress in the development of selective inhibitors of Aurora kinases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Potent and selective Aurora inhibitors identified by the expansion of a novel scaffold for protein kinase inhibition

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Aurora-A - a guardian of poles

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Aurora kinase inhibitor ZM447439 blocks chromosome-induced spindle assembly, the completion of chromosome condensation, and the establishment of the spindle integrity checkpoint in Xenopus egg extracts

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Aurora-kinase inhibitors as anticancer agents

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Aurora kinases link chromosome segregation and cell division to cancer susceptibility

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

The cellular geography of aurora kinases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic Events in HeLa Cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

G1 tetraploidy checkpoint and the suppression of tumorigenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

The kinase activity of aurora B is required for kinetochore-microtubule interactions during mitosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Mitotic kinases as regulators of cell division and its checkpoints

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Validating Aurora B as an anti-cancer drug target.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Roles of aurora-A kinase in mitotic entry and G2 checkpoint in mammalian cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

The non-catalytic domain of the Xenopus laevis auroraA kinase localises the protein to the centrosome.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820716

Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17360485

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0608798104

1 reference

9 August 2017

0 references

1 reference

9 August 2017

1 reference