(Q35678361)

9 August 2017

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title

Manipulation of glycogen-synthase kinase-3 activity in KSHV-associated cancers (English)

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9 August 2017

Masahiro Fujimuro

1

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9 August 2017

S Diane Hayward

series ordinal

2

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9 August 2017

publication date

9 January 2004

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Journal of Molecular Medicine

9 August 2017

published in

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9 August 2017

volume

82

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9 August 2017

issue

4

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9 August 2017

page(s)

223-231

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https://scigraph.springernature.com/pub.10.1007/s00109-003-0519-7

9 August 2017

exact match

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Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling

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Identification of c-MYC as a target of the APC pathway

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p53 inhibition by the LANA protein of KSHV protects against cell death

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Beta-catenin mutations are frequent in human hepatocellular carcinomas associated with hepatitis C virus infection

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Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

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The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus permits replication of terminal repeat-containing plasmids.

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Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma

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Mucosal shedding of human herpesvirus 8 in men.

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The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

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Loss of membranous expression of beta-catenin is associated with tumor progression in cutaneous melanoma and rarely caused by exon 3 mutations

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12 December 2020

Protein interactions targeting the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus to cell chromosomes

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12 December 2020

Detection of human herpesvirus 8 DNA sequences in tissues and bodily fluids

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The Wnt signaling pathway and its role in tumor development

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12 December 2020

Frequent association of beta-catenin and WT1 mutations in Wilms tumors.

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12 December 2020

Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpression

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12 December 2020

Deletions of AXIN1, a component of the WNT/wingless pathway, in sporadic medulloblastomas

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12 December 2020

The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus supports latent DNA replication in dividing cells

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12 December 2020

Genetics of hepatocellular carcinoma

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12 December 2020

Wnt signaling and cancer

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12 December 2020

KSHV (HHV8) infection

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12 December 2020

Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Prolongs the Life Span of Primary Human Umbilical Vein Endothelial Cells

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12 December 2020

TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling

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Alterations of RB1, p53 and Wnt pathways in hepatocellular carcinomas associated with hepatitis C, hepatitis B and alcoholic liver cirrhosis

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12 December 2020

The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

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KSHV ORF K9 (vIRF) is an oncogene which inhibits the interferon signaling pathway

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Expression of vascular endothelial growth factor receptor-3 and podoplanin suggests a lymphatic endothelial cell origin of Kaposi's sarcoma tumor cells.

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

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Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis

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Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin.

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12 December 2020

Structure of GSK3beta reveals a primed phosphorylation mechanism

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12 December 2020

Glycogen synthase kinase-3 beta mutagenesis identifies a common binding domain for GBP and Axin.

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12 December 2020

PECAM-1 (CD31) is expressed on proliferating endothelial cells, stromal spindle-shaped cells, and dermal dendrocytes in Kaposi's sarcoma

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12 December 2020

Gene mutations in lymphoproliferative disorders of T and NK/T cell phenotypes developing in renal transplant patients

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12 December 2020

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12 December 2020

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12 December 2020

Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer

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12 December 2020

Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

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12 December 2020

The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus interacts preferentially with the terminal repeats of the genome in vivo and this complex is sufficient for episomal DNA replication

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12 December 2020

Skin cancers after organ transplantation

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12 December 2020

Differential viral protein expression in Kaposi's sarcoma-associated herpesvirus-infected diseases: Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease.

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12 December 2020

CD40 antigen is expressed by endothelial cells and tumor cells in Kaposi's sarcoma

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12 December 2020

Beta-catenin mutations in human prostate cancer.

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12 December 2020

Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes

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12 December 2020

KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma

1 reference

12 December 2020

Beta-catenin mutations are associated with a subset of low-stage hepatocellular carcinoma negative for hepatitis B virus and with favorable prognosis

1 reference

12 December 2020

A new primary effusion lymphoma-derived cell line yields a highly infectious Kaposi's sarcoma herpesvirus-containing supernatant

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12 December 2020

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

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12 December 2020

Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta

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12 December 2020

KSHV/HHV8-associated lymphoproliferations in the AIDS setting

1 reference

12 December 2020

The molecular pathology of Kaposi's sarcoma-associated herpesvirus

1 reference

12 December 2020

A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin

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12 December 2020

Novel organizational features, captured cellular genes, and strain variability within the genome of KSHV/HHV8.

1 reference

12 December 2020

Expression of the open reading frame 74 (G-protein-coupled receptor) gene of Kaposi's sarcoma (KS)-associated herpesvirus: implications for KS pathogenesis

1 reference

12 December 2020

Identification of the Axin and Frat binding region of glycogen synthase kinase-3.

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12 December 2020

Sequence variants of the axin gene in breast, colon, and other cancers: an analysis of mutations that interfere with GSK3 binding

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12 December 2020

Expression of human herpesvirus 8 in primary pulmonary hypertension

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12 December 2020

Abnormalities of the APC/beta-catenin pathway in endometrial cancer

1 reference

12 December 2020

beta-Catenin mutation is a frequent cause of Wnt pathway activation in gastric cancer.

1 reference

12 December 2020

Latency-associated nuclear antigen (LANA) cooperatively binds to two sites within the terminal repeat, and both sites contribute to the ability of LANA to suppress transcription and to facilitate DNA replication

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12 December 2020

Phenotypic characteristics of Kaposi's sarcoma tumour cells derived from patch-, plaque- and nodular-stage lesions: analysis of cell cultures isolated from AIDS and non-AIDS patients and review of the literature

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12 December 2020

Beta-catenin and E-cadherin expression patterns in high-grade endometrial carcinoma are associated with histological subtype.

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12 December 2020

Identification of a Wnt-responsive signal transduction pathway in primary endothelial cells

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12 December 2020

Kaposi's sarcoma herpesvirus as a new paradigm for virus-induced oncogenesis.

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12 December 2020

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

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12 December 2020

AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

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12 December 2020

Wnt pathway activation in mesothelioma: evidence of Dishevelled overexpression and transcriptional activity of beta-catenin

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12 December 2020

Wnt signaling in hepatocellular carcinoma: analysis of mutation and expression of beta-catenin, T-cell factor-4 and glycogen synthase kinase 3-beta genes.

1 reference

12 December 2020

beta-catenin is a target for the ubiquitin-proteasome pathway

1 reference

12 December 2020

Chromosome binding site of latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus is essential for persistent episome maintenance and is functionally replaced by histone H1

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12 December 2020

Epstein-Barr virus-recent advances

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12 December 2020

Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC

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12 December 2020

Direct, activating interaction between glycogen synthase kinase-3beta and p53 after DNA damage

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12 December 2020

A novel viral mechanism for dysregulation of beta-catenin in Kaposi's sarcoma-associated herpesvirus latency.

1 reference

12 December 2020

arrow encodes an LDL-receptor-related protein essential for Wingless signalling

1 reference

12 December 2020

Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen

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12 December 2020

Molecular cloning and expression of glycogen synthase kinase-3/factor A

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12 December 2020

Immunoglobulin VH gene mutational analysis suggests that primary effusion lymphomas derive from different stages of B cell maturation

1 reference

12 December 2020

The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation

1 reference

12 December 2020

The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus): distribution of infection in KS risk groups and evidence for sexual transmission

1 reference

12 December 2020

Epstein-Barr virus and oncogenesis: from latent genes to tumours

1 reference

12 December 2020

Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

1 reference

12 December 2020

Detection and analysis of beta-catenin mutations in prostate cancer

1 reference

12 December 2020

BP75, bromodomain-containing M(r) 75,000 protein, binds dishevelled-1 and enhances Wnt signaling by inactivating glycogen synthase kinase-3 beta.

1 reference

12 December 2020

CREB DNA binding activity is inhibited by glycogen synthase kinase-3 beta and facilitated by lithium

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12 December 2020

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

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12 December 2020

Glycogen Synthase Kinase-3β (GSK3β) Binds to and Promotes the Actions of p53

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12 December 2020

Kaposi sarcoma-associated herpesvirus infects monotypic (IgM lambda) but polyclonal naive B cells in Castleman disease and associated lymphoproliferative disorders.

1 reference

12 December 2020

beta-Catenin mutation and overexpression in hepatocellular carcinoma: clinicopathologic and prognostic significance.

1 reference

12 December 2020

Wnt signaling in breast cancer: have we come full circle?

1 reference

12 December 2020

The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus manipulates the activity of glycogen synthase kinase-3beta

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12 December 2020

The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells

1 reference

12 December 2020

A role for the beta-catenin/T-cell factor signaling cascade in vascular remodeling

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12 December 2020

Patterns of gene expression and a transactivation function exhibited by the vGCR (ORF74) chemokine receptor protein of Kaposi's sarcoma-associated herpesvirus

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12 December 2020

Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex

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12 December 2020

Beta-catenin mutations correlate with over expression of C-myc and cyclin D1 Genes in bladder cancer

1 reference

12 December 2020

APC/CTNNB1 (?-catenin) pathway alterations in human prostate cancers

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12 December 2020

10.1007/S00109-003-0519-7

Identifiers

DOI

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9 August 2017

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