(Q35681624)

9 August 2017

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title

The role of the guanine nucleotide exchange factor Tiam1 in cellular migration, invasion, adhesion and tumor progression (English)

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9 August 2017

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Meghan E Minard

1

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9 August 2017

Lee-Su Kim

series ordinal

2

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9 August 2017

Janet E Price

series ordinal

3

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9 August 2017

Gary E Gallick

series ordinal

4

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9 August 2017

language of work or name

English

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publication date

1 March 2004

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Breast Cancer Research and Treatment

9 August 2017

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9 August 2017

84

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9 August 2017

21-32

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9 August 2017

1

1 reference

https://scigraph.springernature.com/pub.10.1023/b:brea.0000018421.31632.e6

9 August 2017

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cites work

Selective inhibitory effect of bufalin on growth of human tumor cells in vitro: association with the induction of apoptosis in leukemia HL-60 cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

The bioactive phospholipid lysophosphatidic acid is released from activated platelets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

Rho proteins, PI 3-kinases, and monocyte/macrophage motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Signaling to the Rho GTPases: networking with the DH domain

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

The invasion-inducing TIAM1 gene maps to human chromosome band 21q22 and mouse chromosome 16.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Localization of a human homolog of the mouse Tiam-1 gene to chromosome 21q22.1.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

DHR domains in syntrophins, neuronal NO synthases and other intracellular proteins

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

A role for Rac in Tiam1-induced membrane ruffling and invasion

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Translocation of the Rac1 guanine nucleotide exchange factor Tiam1 induced by platelet-derived growth factor and lysophosphatidic acid

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Lysophosphatidic acid induces threonine phosphorylation of Tiam1 in Swiss 3T3 fibroblasts via activation of protein kinase C.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Phospholipase C-gamma, protein kinase C and Ca2+/calmodulin-dependent protein kinase II are involved in platelet-derived growth factor-induced phosphorylation of Tiam1.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Bufalin induces apoptosis and influences the expression of apoptosis-related genes in human leukemia cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Bufalin as a potent inducer of differentiation of human myeloid leukemia cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Tiam1 is involved in the regulation of bufalin-induced apoptosis in human leukemia cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Regulation of Tiam1 nucleotide exchange activity by pleckstrin domain binding ligands

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Stimulation of phospholipase D by epidermal growth factor requires protein kinase C activation in Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Evidence for a novel gene associated with low tumor metastatic potential

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Expression of Tiam-1 in the developing brain suggests a role for the Tiam-1-Rac signaling pathway in cell migration and neurite outgrowth.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Evidence for the involvement of Tiam1 in axon formation

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Inhibition of invasion of epithelial cells by Tiam1-Rac signaling

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Tiam1 mutations in human renal-cell carcinomas

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Ankyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migration

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Tiam1 overexpression potentiates heregulin-induced lymphoid enhancer factor-1/beta -catenin nuclear signaling in breast cancer cells by modulating the intercellular stability

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Increased levels of alpha6 integrins are associated with the metastatic phenotype of human breast cancer cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

Molecular cytogenetic analysis of 11 new breast cancer cell lines

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000018421.31632.E6

7 January 2021

10.1023/B:BREA.0000018421.31632.E6

Identifiers

DOI

1 reference

Dimensions Publication ID

9 August 2017

0 references

1 reference