(Q35681957)

9 August 2017

title

Indole-3-carbinol synergistically sensitises ovarian cancer cells to bortezomib treatment (English)

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9 August 2017

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B Taylor-Harding

1

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9 August 2017

H Agadjanian

2

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9 August 2017

H Nassanian

3

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9 August 2017

S Kwon

4

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9 August 2017

X Guo

5

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9 August 2017

C Miller

6

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9 August 2017

B Y Karlan

7

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9 August 2017

S Orsulic

8

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9 August 2017

C S Walsh

9

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9 August 2017

language of work or name

English

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publication date

13 December 2011

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British Journal of Cancer

9 August 2017

published in

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9 August 2017

volume

106

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9 August 2017

issue

2

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9 August 2017

page(s)

333-343

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describes a project that uses

9 August 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3261668

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/bjc.2011.546

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cites work

Fluvastatin and cisplatin demonstrate synergistic cytotoxicity in epithelial ovarian cancer cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Combination Therapy of Bortezomib with Novel Targeted Agents: An Emerging Treatment Strategy

27 July 2018

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Gene amplification CCNE1 is related to poor survival and potential therapeutic target in ovarian cancer

27 July 2018

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Identification of genes with differential expression in chemoresistant epithelial ovarian cancer using high-density oligonucleotide microarrays

27 July 2018

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Collagen and calcium-binding EGF domains 1 is frequently inactivated in ovarian cancer by aberrant promoter hypermethylation and modulates cell migration and survival

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Bortezomib-mediated expression of p27Kip1 through S-phase kinase protein 2 degradation in epithelial ovarian cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

The biology of ovarian cancer: new opportunities for translation

27 July 2018

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Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Bortezomib treatment of ovarian cancer cells mediates endoplasmic reticulum stress, cell cycle arrest, and apoptosis

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

TOP2A overexpression in hepatocellular carcinoma correlates with early age onset, shorter patients survival and chemoresistance

27 July 2018

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Synergistic action of dietary phyto-antioxidants on survival and proliferation of ovarian cancer cells

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Drug development of MET inhibitors: targeting oncogene addiction and expedience

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer.

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Indole-3-carbinol as a chemopreventive and anti-cancer agent

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Early events in the pathogenesis of epithelial ovarian cancer

27 July 2018

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Phase I trial of the proteasome inhibitor bortezomib in combination with carboplatin in patients with platinum- and taxane-resistant ovarian cancer

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Both mammalian PIG-M and PIG-X are required for growth of GPI14-disrupted yeast

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Using GOstats to test gene lists for GO term association

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Proteasome inhibitor induces apoptosis through induction of endoplasmic reticulum stress.

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype

27 July 2018

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Gene expression profiling revealed survivin as a target of 3,3'-diindolylmethane-induced cell growth inhibition and apoptosis in breast cancer cells

27 July 2018

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Preclinical evaluation of the proteasome inhibitor bortezomib in cancer therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Indole-3-carbinol for recurrent respiratory papillomatosis: long-term results

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Met, metastasis, motility and more

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

PIG-M transfers the first mannose to glycosylphosphatidylinositol on the lumenal side of the ER.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Proteasome inhibitor induced gene expression profiles reveal overexpression of transcriptional regulators ATF3, GADD153 and MAD1.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Heat shock factors and the control of the stress response

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

A phase II evaluation of bortezomib in the treatment of recurrent platinum-sensitive ovarian or primary peritoneal cancer: a Gynecologic Oncology Group study

27 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.546

Phase I trial of bortezomib and carboplatin in recurrent ovarian or primary peritoneal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.546

Phase I study of bortezomib with weekly paclitaxel in patients with advanced solid tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.546

The hepatocyte growth factor/Met pathway controls proliferation and apoptosis in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.546

lumi: a pipeline for processing Illumina microarray

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.546

Value of integrated positron emission tomography revised using a phantom study to evaluate malignancy grade of lung adenocarcinoma: a multicenter study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.546

The dietary phytochemical indole-3-carbinol is a natural elastase enzymatic inhibitor that disrupts cyclin E protein processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.546

A phase I study of indole-3-carbinol in women: tolerability and effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.546

Novel proteasome inhibitors to overcome bortezomib resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FBJC.2011.546

Snail is critical for tumor growth and metastasis of ovarian carcinoma

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Gene expression profiles of I3C- and DIM-treated PC3 human prostate cancer cells determined by cDNA microarray analysis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261668

Overexpression of c-Met and of the transducers PI3K, FAK and JAK in breast carcinomas correlates with shorter survival and neoangiogenesis

25 September 2018

1 reference

12 December 2020

Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways

1 reference

12 December 2020

Whole genome expression profiling of advance stage papillary serous ovarian cancer reveals activated pathways

1 reference

12 December 2020

Targeting the c-MET signaling pathway for cancer therapy

1 reference

12 December 2020

A randomized phase II trial of indole-3-carbinol in the treatment of vulvar intraepithelial neoplasia

1 reference

12 December 2020

Identifiers

DOI

10.1038/BJC.2011.546

1 reference

9 August 2017

1 reference

9 August 2017

1 reference