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Role of imbalance between neutrophil elastase and alpha 1-antitrypsin in cancer development and progression.
scientific article published on March 2004
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Europe PubMed Central
PubMed publication ID
15003202
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003202%20AND%20SRC:MED&resulttype=core&format=json
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25 December 2019
review article
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title
Role of imbalance between neutrophil elastase and alpha 1-antitrypsin in cancer development and progression
(English)
1 reference
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Europe PubMed Central
PubMed publication ID
15003202
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003202%20AND%20SRC:MED&resulttype=core&format=json
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25 December 2019
author
Zhifu Sun
series ordinal
1
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Europe PubMed Central
PubMed publication ID
15003202
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003202%20AND%20SRC:MED&resulttype=core&format=json
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25 December 2019
author name string
Ping Yang
series ordinal
2
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Europe PubMed Central
PubMed publication ID
15003202
reference URL
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25 December 2019
publication date
1 March 2004
1 reference
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Europe PubMed Central
PubMed publication ID
15003202
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003202%20AND%20SRC:MED&resulttype=core&format=json
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25 December 2019
published in
Lancet Oncology Commission
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Europe PubMed Central
PubMed publication ID
15003202
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 December 2019
volume
5
1 reference
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Europe PubMed Central
PubMed publication ID
15003202
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 December 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15003202
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 December 2019
page(s)
182-190
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15003202
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 December 2019
cites work
Alpha-1 antitrypsin deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha1-antitrypsin deficiency: biological answers to clinical questions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the ELA2 gene encoding neutrophil elastase are present in most patients with sporadic severe congenital neutropenia but only in some patients with the familial form of the disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Paternal mosaicism proves the pathogenic nature of mutations in neutrophil elastase in severe congenital neutropenia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in ELA2, encoding neutrophil elastase, define a 21-day biological clock in cyclic haematopoiesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the neutrophil elastase gene in cyclic and congenital neutropenia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The alpha 1-antitrypsin gene and its deficiency states
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Electrophoretic α;1-Globulin Pattern of Serum in α;1-Antitrypsin Deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distribution of alpha 1-antitrypsin variants in a US white population
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha 1-antitrypsin deficiency in Europe: geographical distribution of Pi types S and Z
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Population Genetics of Alpha-1-Antitrypsin Polymorphism in US Whites, US Blacks and African Blacks
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Worldwide racial and ethnic distribution of alpha1-antitrypsin deficiency: summary of an analysis of published genetic epidemiologic surveys
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Outcome of liver disease associated with alpha 1 antitrypsin deficiency (PiZ). Implications for genetic counselling and antenatal diagnosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The natural history of liver disease in alpha 1-antitrypsin deficient children
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recent pulmonary observations in alpha 1-antitrypsin deficiency, primary biliary cirrhosis, chronic hepatitis C, and other hepatic problems
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of age and occupational exposure to airway irritants on lung function in non-smoking individuals with alpha 1-antitrypsin deficiency (PiZZ).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Late manifestation of chronic liver disease in adults with alpha-1-antitrypsin deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cirrhosis and hepatocellular carcinoma in a patient with heterozygous (MZ) alpha-1-antitrypsin deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic 'cryptogenic' liver disease and malignant hepatoma in intermediate alpha 1-antitrypsin deficiency identified by a Pi Z-specific monoclonal antibody
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevalence of hepatocellular carcinoma in alpha-1-antitrypsin deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is heterozygous alpha-1-antitrypsin deficiency type PIZ a risk factor for primary liver carcinoma?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of increase in heterozygous α1-antitrypsin deficiency phenotypes among patients with hepatocellular and bile duct carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distribution of alpha-1-antitrypsin and haptoglobin phenotypes in bladder cancer patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smoking, lung function, and alpha 1-antitrypsin deficiency.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of alpha 1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Higher risk of mismatch repair-deficient colorectal cancer in alpha(1)-antitrypsin deficiency carriers and cigarette smokers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha-1-antitrypsin (AAT) deposits in gall bladder adenocarcinoma and liver in partial AAT deficiency (Pi SZ phenotype)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alpha-1-antitrypsin phenotypes in malignant lymphoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Higher risk of lung cancer in chronic obstructive pulmonary disease. A prospective, matched, controlled study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Airways obstruction and the risk for lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lung cancer risk in families of nonsmoking probands: heterogeneity by age at diagnosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Primary structure of human neutrophil elastase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of neutrophil elastase in acute lung injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neutrophil elastase enzymatically antagonizes the in vitro action of G-CSF: implications for the regulation of granulopoiesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteolytic cleavage of granulocyte colony‐stimulating factor and its receptor by neutrophil elastase induces growth inhibition and decreased cell surface expression of the granulocyte colony‐stimulating factor receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leukocyte elastase negatively regulates Stromal cell-derived factor-1 (SDF-1)/CXCR4 binding and functions by amino-terminal processing of SDF-1 and CXCR4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neutrophil elastase: alpha-1-proteinase inhibitor complex in serum and bronchoalveolar lavage fluid in patients with pulmonary fibrosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhancer function of a 53-bp repetitive element in the 5' flanking region of the human neutrophil elastase gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of neutrophil elastase suppresses the development of skin tumors in hairless mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neutrophil elastase inhibitor reduces hepatic metastases induced by ischaemia-reperfusion in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor neutrophil elastase is closely associated with the direct extension of non-small cell lung cancer into the aorta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Local increase in polymorphonuclear leukocyte elastase is associated with tumor invasiveness in non-small cell lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Free-form neutrophil elastase is an independent marker predicting recurrence in primary breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Production of immunoreactive polymorphonuclear leucocyte elastase in human breast cancer cells: possible role of polymorphonuclear leucocyte elastase in the progression of human breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of progelatinase A (MMP-2) by neutrophil elastase, cathepsin G, and proteinase-3: a role for inflammatory cells in tumor invasion and angiogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of matrix metalloproteinase 3 (stromelysin) and matrix metalloproteinase 2 ('gelatinase') by human neutrophil elastase and cathepsin G
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Matrix metalloproteinases: biologic activity and clinical implications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neutrophil-derived serine proteinases enhance membrane type-1 matrix metalloproteinase-dependent tumor cell invasion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TNF-R1 signaling: a beautiful pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
cJun overexpression in MCF-7 breast cancer cells produces a tumorigenic, invasive and hormone resistant phenotype
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene therapy approaches for inherited and acquired lung diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene therapy for lung inflammatory diseases: not so far away?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901414-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1470-2045(04)01414-7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15003202
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 December 2019
PubMed publication ID
15003202
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15003202
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003202%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 December 2019
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