(Q35687951)

9 August 2017

title

Polyvalent dendrimer-methotrexate as a folate receptor-targeted cancer therapeutic (English)

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9 August 2017

1 reference

3

Seok Ki Choi

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9 August 2017

10

James R Baker

1 reference

9 August 2017

Thommey P Thomas

1

1 reference

9 August 2017

Baohua Huang

2

1 reference

9 August 2017

Justin E Silpe

4

1 reference

9 August 2017

Alina Kotlyar

5

1 reference

9 August 2017

Ankur M Desai

6

1 reference

9 August 2017

Hong Zong

7

1 reference

9 August 2017

Jeremy Gam

8

1 reference

9 August 2017

Melvin Joice

9

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9 August 2017

language of work or name

English

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publication date

7 August 2012

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9 August 2017

published in

Molecular Pharmaceutics

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9 August 2017

volume

9

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9 August 2017

issue

9

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9 August 2017

page(s)

2669-2676

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Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting.

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Folate-targeted nanoparticles show efficacy in the treatment of inflammatory arthritis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Copper-free click conjugation of methotrexate to a PAMAM dendrimer platform

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Design of riboflavin-presenting PAMAM dendrimers as a new nanoplatform for cancer-targeted delivery

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Understanding specific and nonspecific toxicities: a requirement for the development of dendrimer-based pharmaceuticals

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

A quantitative assessment of nanoparticle-ligand distributions: implications for targeted drug and imaging delivery in dendrimer conjugates

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Targeted dendrimeric anticancer prodrug: a methotrexate-folic acid-poly(amidoamine) conjugate and a novel, rapid, "one pot" synthetic approach

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

PEGylated PAMAM dendrimers as a potential drug delivery carrier: in vitro and in vivo comparative evaluation of covalently conjugated drug and noncovalent drug inclusion complex

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Methotrexate delivery via folate targeted dendrimer-based nanotherapeutic platform

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Binding affinity and kinetic analysis of targeted small molecule-modified nanoparticles.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Dendrimers: emerging polymers for drug-delivery systems

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Folate receptor targeted bimodal liposomes for tumor magnetic resonance imaging

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Nanoparticle therapeutics: an emerging treatment modality for cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

The design of polyvalent therapeutics.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Investigation of tumor cell targeting of a dendrimer nanoparticle using a double-clad optical fiber probe

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Dendrimer-epidermal growth factor conjugate displays superagonist activity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Polymer conjugates as anticancer nanomedicines

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Polymer therapeutics: concepts and applications

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Dendrimers and dendritic polymers in drug delivery

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Folate-targeted chemotherapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Antifolates targeted specifically to the folate receptor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

High-avidity, low-affinity multivalent interactions and the block to polyspermy in Xenopus laevis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Overexpression of folate binding protein in ovarian cancers.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Dihydrofolate reductase from Lactobacillus casei. X-ray structure of the enzyme methotrexate.NADPH complex

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Bioanalytical Screening of Riboflavin Antagonists for Targeted Drug Delivery - A Thermodynamic and Kinetic Study

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Strain-promoted alkyne azide cycloaddition for the functionalization of poly(amide)-based dendrons and dendrimers.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

The binding avidity of a nanoparticle-based multivalent targeted drug delivery platform.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Activity of dendrimer-methotrexate conjugates on methotrexate-sensitive and -resistant cell lines

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Poly(amidoamine) dendrimer-based multifunctional engineered nanodevice for cancer therapy

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Targeting and inhibition of cell growth by an engineered dendritic nanodevice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Folate receptor endocytosis and trafficking

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Analysis of exponential data using a noniterative technique: application to surface plasmon experiments.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Design and function of a dendrimer-based therapeutic nanodevice targeted to tumor cells through the folate receptor

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Selective immobilization of multivalent ligands for surface plasmon resonance and fluorescence microscopy

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457335

Translating cancer research into targeted therapeutics

25 September 2018

1 reference

12 December 2020

Capping Methotrexate α-Carboxyl Groups Enhances Systemic Exposure and Retains the Cytotoxicity of Drug Conjugated PEGylated Polylysine Dendrimers

1 reference

12 December 2020

Bifunctional PAMAM dendrimer conjugates of folic acid and methotrexate with defined ratio

1 reference

12 December 2020

Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors

1 reference

12 December 2020

The influence of extracellular folate concentration on methotrexate uptake by human KB cells. Partial characterization of a membrane-associated methotrexate binding protein

1 reference

12 December 2020

Prolonged inhibition of DNA synthesis associated with the accumulation of methotrexate polyglutamates by cultured human cells

1 reference

12 December 2020

Functional activity of the reduced folate carrier in KB, MA104, and IGROV-I cells expressing folate-binding protein

1 reference

12 December 2020

High affinity binding of the Entamoeba histolytica lectin to polyvalent N-acetylgalactosaminides

1 reference

12 December 2020

Identifiers

DOI

10.1021/MP3002232

1 reference

9 August 2017

1 reference

9 August 2017

1 reference