(Q35688037)

9 August 2017

title

Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder (English)

1 reference

9 August 2017

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9

Ted M Dawson

1 reference

9 August 2017

Wei Lu

1

1 reference

9 August 2017

Senthilkumar S Karuppagounder

2

1 reference

9 August 2017

Danielle A Springer

3

1 reference

9 August 2017

Michele D Allen

4

1 reference

9 August 2017

Lixin Zheng

5

1 reference

9 August 2017

Brittany Chao

6

1 reference

9 August 2017

Yan Zhang

7

1 reference

9 August 2017

Valina L Dawson

8

1 reference

9 August 2017

Michael Lenardo

10

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9 August 2017

language of work or name

English

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publication date

15 September 2014

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9 August 2017

published in

Nature Communications

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9 August 2017

volume

5

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9 August 2017

page(s)

4930

1 reference

https://scigraph.springernature.com/pub.10.1038/ncomms5930

9 August 2017

exact match

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cites work

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27 July 2018

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Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5

27 July 2018

1 reference

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Mitochondrial dynamics and neuronal fate in Parkinson's disease.

27 July 2018

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Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment

27 July 2018

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The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways

27 July 2018

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Mitochondrial dynamics and mitophagy in Parkinson's disease: disordered cellular power plant becomes a big deal in a major movement disorder

27 July 2018

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What genetics tells us about the causes and mechanisms of Parkinson's disease

27 July 2018

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27 July 2018

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27 July 2018

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PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function

27 July 2018

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27 July 2018

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PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease

27 July 2018

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27 July 2018

Mechanisms of mitophagy

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The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila

27 July 2018

1 reference

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Selective neuronal vulnerability to oxidative stress in the brain

27 July 2018

1 reference

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Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

27 July 2018

1 reference

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Autophagy in health and disease. 5. Mitophagy as a way of life

27 July 2018

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Behavioral phenotyping of mouse models of Parkinson's disease

27 July 2018

1 reference

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PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Tests to assess motor phenotype in mice: a user's guide

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Poly(ADP-ribose) signals to mitochondrial AIF: a key event in parthanatos

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Mitochondrial dysfunction in the limelight of Parkinson's disease pathogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Gait analysis in a murine model of collagen-induced arthritis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Diagnosis and treatment of Parkinson disease: molecules to medicine

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Epidemiology of Parkinson's disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Genetics of Parkinson disease: paradigm shifts and future prospects.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Mitochondria: master regulators of danger signalling

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Regulation of PINK1-Parkin-mediated mitophagy.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Induction of intestinal Th17 cells by segmented filamentous bacteria

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Abnormal gait, due to inflammation but not nerve injury, reflects enhanced nociception in preclinical pain models

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Addressing membrane protein topology using the fluorescence protease protection (FPP) assay.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

3,4-dihydroxyphenylalanine reverses the motor deficits in Pitx3-deficient aphakia mice: behavioral characterization of a novel genetic model of Parkinson's disease.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

Pole test is a useful method for evaluating the mouse movement disorder caused by striatal dopamine depletion.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457367

25 September 2018

Identifiers

DOI

10.1038/NCOMMS5930

1 reference

release_562jyeldu5gjzbj3pzlaj3ezd4

9 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/562jyeldu5gjzbj3pzlaj3ezd4

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4457367

1 reference

9 August 2017

1 reference