(Q35689250)

English

E1210, a new broad-spectrum antifungal, suppresses Candida albicans hyphal growth through inhibition of glycosylphosphatidylinositol biosynthesis

scientific article published on 5 December 2011

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143530%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

E1210, a new broad-spectrum antifungal, suppresses Candida albicans hyphal growth through inhibition of glycosylphosphatidylinositol biosynthesis (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143530%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Inositol acyltransferase with a predicted role in GPI anchor biosynthesis

1 reference

5 February 2019

Candida albicans

1 reference

based on heuristic

inferred from title

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143530%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Nao-Aki Watanabe

1

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17 January 2020

Mamiko Miyazaki

2

1 reference

Europe PubMed Central

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17 January 2020

Takaaki Horii

3

1 reference

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17 January 2020

Kappei Tsukahara

5

1 reference

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17 January 2020

Katsura Hata

6

1 reference

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17 January 2020

language of work or name

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publication date

5 December 2011

1 reference

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17 January 2020

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

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17 January 2020

56

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Europe PubMed Central

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17 January 2020

2

1 reference

Europe PubMed Central

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17 January 2020

960-971

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143530%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

In vitro activity of E1210, a novel antifungal, against clinically important yeasts and molds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Efficacy of oral E1210, a new broad-spectrum antifungal with a novel mechanism of action, in murine models of candidiasis, aspergillosis, and fusariosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Characterisation of Pga1, a putative Candida albicans cell wall protein necessary for proper adhesion and biofilm formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Therapy for fungal diseases: opportunities and priorities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2007: a 10.5-year analysis of susceptibilities of Candida Species to fluconazole and voriconazole as determined by CLSI standardized disk diffusion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Forward genetics in Candida albicans that reveals the Arp2/3 complex is required for hyphal formation, but not endocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

In vitro activity of micafungin against planktonic and sessile Candida albicans isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Candida albicans cell wall proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Aspergillus fumigatus forms biofilms with reduced antifungal drug susceptibility on bronchial epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

In vitro survey of triazole cross-resistance among more than 700 clinical isolates of Aspergillus species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Gene overexpression/suppression analysis of candidate virulence factors of Candida albicans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Eap1p, an adhesin that mediates Candida albicans biofilm formation in vitro and in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Thematic review series: lipid posttranslational modifications. GPI anchoring of protein in yeast and mammalian cells, or: how we learned to stop worrying and love glycophospholipids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Trends in the epidemiology of invasive fungal infections.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Comprehensive analysis of glycosylphosphatidylinositol-anchored proteins in Candida albicans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Function of Candida albicans adhesin Hwp1 in biofilm formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Biosynthesis and function of GPI proteins in the yeast Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Inactivation of the phospholipase B gene PLB5 in wild-type Candida albicans reduces cell-associated phospholipase A2 activity and attenuates virulence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

International surveillance of Candida spp. and Aspergillus spp.: report from the SENTRY Antimicrobial Surveillance Program (2003).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Farnesol concentrations required to block germ tube formation in Candida albicans in the presence and absence of serum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Candida biofilms: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Small-molecule inhibitors of the budded-to-hyphal-form transition in the pathogenic yeast Candida albicans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Development and characterization of an in vivo central venous catheter Candida albicans biofilm model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Functional and structural diversity in the Als protein family of Candida albicans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Superoxide Dismutases inCandida albicans: Transcriptional Regulation and Functional Characterization of the Hyphal-inducedSOD5Gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

PIG-W Is Critical for Inositol Acylation but Not for Flipping of Glycosylphosphatidylinositol-Anchor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Sensitive Assay for Antifungal Activity of Glucan Synthase Inhibitors That Uses Germ Tube Formation in Candida albicans as an End Point

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Inhibitors of glycosyl-phosphatidylinositol anchor biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

GWT1 gene is required for inositol acylation of glycosylphosphatidylinositol anchors in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Candida albicans Mds3p, a conserved regulator of pH responses and virulence identified through insertional mutagenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

In vitro activity of caspofungin against Candida albicans biofilms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Standardized method for in vitro antifungal susceptibility testing of Candida albicans biofilms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

The ALS gene family of Candida albicans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

The GPI biosynthetic pathway as a therapeutic target for African sleeping sickness.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Identification of a species-specific inhibitor of glycosylphosphatidylinositol synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

The effects of antifungal agents on the morphogenetic transformation by Candida albicans in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Adherence of Candida albicans germ tubes to plastic: ultrastructural and molecular studies of fibrillar adhesins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Inositol acylation of a potential glycosyl phosphoinositol anchor precursor from yeast requires acyl coenzyme A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

The Candida albicans homologue of PIG-P, CaGpi19p: gene dosage and role in growth and filamentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

25 September 2018

Synthesis and evaluation of novel antifungal agents-quinoline and pyridine amide derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

25 September 2018

Identification of Candida albicans exposed surface proteins in vivo by a rapid proteomic approach.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

25 September 2018

MPR1 as a novel selection marker in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

25 September 2018

Epidemiology and outcome of invasive fungal infection in adult hematopoietic stem cell transplant recipients: analysis of Multicenter Prospective Antifungal Therapy (PATH) Alliance registry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

25 September 2018

Complementary adhesin function in C. albicans biofilm formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

25 September 2018

In vitro effects of micafungin against Candida biofilms on polystyrene and central venous catheter sections.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

25 September 2018

Glycosylphosphatidylinositol-anchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

25 September 2018

Deficiencies in the essential Smp3 mannosyltransferase block glycosylphosphatidylinositol assembly and lead to defects in growth and cell wall biogenesis in Candida albicans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

25 September 2018

Medicinal genetics approach towards identifying the molecular target of a novel inhibitor of fungal cell wall assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

25 September 2018

Complete glycosylphosphatidylinositol anchors are required in Candida albicans for full morphogenesis, virulence and resistance to macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

25 September 2018

The cell wall architecture of Candida albicans wild-type cells and cell wall-defective mutants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

25 September 2018

Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

25 September 2018

Effect of amphotericin B, fluconazole and itraconazole on intracellular Candida albicans and germ tube development in macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/22143530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A conditionally lethal yeast mutant blocked at the first step in glycosyl phosphatidylinositol anchor synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22143530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid colorimetric assay for determination of leukocyte-mediated inhibition of mycelial growth of Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/22143530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Architecture of the yeast cell wall. Beta(1-->6)-glucan interconnects mannoprotein, beta(1-->)3-glucan, and chitin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22143530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple-Triazole–Resistant Aspergillosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22143530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changing pattern of candidaemia 2001-2006 and use of antifungal therapy at the University Hospital of Vienna, Austria

1 reference

https://pubmed.ncbi.nlm.nih.gov/22143530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of inositol acylation and inositol deacylation in the Toxoplasma gondii glycosylphosphatidylinositol biosynthetic pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22143530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Filamentous growth of Candida albicans in response to physical environmental cues and its regulation by the unique CZF1 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/22143530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An amino acid liquid synthetic medium for the development of mycelial and yeast forms of Candida Albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/22143530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.00731-11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143530%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143530%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143530%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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