(Q35694476)

English

Synthesis and evaluation of 1,5-disubstituted tetrazoles as rigid analogues of combretastatin A-4 with potent antiproliferative and antitumor activity

scientific article published on 21 December 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Synthesis and evaluation of 1,5-disubstituted tetrazoles as rigid analogues of combretastatin A-4 with potent antiproliferative and antitumor activity (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

object named as

Delia Preti

4

0 references

Andrea Brancale

object named as

Andrea Brancale

6

0 references

object named as

Giuseppe Basso

12

0 references

Giampietro Viola

13

object named as

Giampietro Viola

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

author name string

Romeo Romagnoli

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Pier Giovanni Baraldi

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Maria Kimatrai Salvador

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Mojgan Aghazadeh Tabrizi

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Xian-Hua Fu

7

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Jun Li

8

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Su-Zhan Zhang

9

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Ernest Hamel

10

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Roberta Bortolozzi

11

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

language of work or name

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publication date

21 December 2011

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Journal of Medicinal Chemistry

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Europe PubMed Central

PubMed publication ID

9 August 2017

55

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

475-488

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266058

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Microtubule-binding agents: a dynamic field of cancer therapeutics

1 reference

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12 July 2018

4-(3-Halo/amino-4,5-dimethoxyphenyl)-5-aryloxazoles and -N-methylimidazoles That Are Cytotoxic against Combretastatin A Resistant Tumor Cells and Vascular Disrupting in a Cisplatin Resistant Germ Cell Tumor Model

1 reference

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Multiple drug resistance mechanisms in cancer

1 reference

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12 July 2018

Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues

1 reference

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12 July 2018

Vascular disrupting activity of tubulin-binding 1,5-diaryl-1H-imidazoles

1 reference

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Microtubule depolymerizing vascular disrupting agents: novel therapeutic agents for oncology and other pathologies

1 reference

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Cell-cycle control in the face of damage--a matter of life or death.

1 reference

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Tubulin-interactive natural products as anticancer agents

1 reference

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Microtubule dynamics as a target in oncology

1 reference

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In vivo roles of CDC25 phosphatases: biological insight into the anti-cancer therapeutic targets

1 reference

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12 July 2018

1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin

1 reference

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12 July 2018

Combretastatin a-4 analogs as anticancer agents

1 reference

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Central role of mitochondria and p53 in PUVA-induced apoptosis in human keratinocytes cell line NCTC-2544.

1 reference

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The microtubule-targeting agent CA4P regresses leukemic xenografts by disrupting interaction with vascular cells and mitochondrial-dependent cell death

1 reference

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12 July 2018

Highly potent triazole-based tubulin polymerization inhibitors

1 reference

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12 July 2018

Synthesis and activity of Combretastatin A-4 analogues: 1,2,3-thiadiazoles as potent antitumor agents

1 reference

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12 July 2018

Medicinal chemistry of combretastatin A4: present and future directions.

1 reference

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Targeting multidrug resistance in cancer

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12 July 2018

Isoxazole-type derivatives related to combretastatin A-4, synthesis and biological evaluation.

1 reference

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12 July 2018

Understanding microtubule dynamics for improved cancer therapy.

1 reference

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Pharmaceutical design of antimitotic agents based on combretastatins.

1 reference

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Intracellular generation of reactive oxygen species by mitochondria

1 reference

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The pathophysiology of mitochondrial cell death

1 reference

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Structural requirements for the interaction of combretastatins with tubulin: how important is the trimethoxy unit?

1 reference

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Microtubules, microtubule-interfering agents and apoptosis.

1 reference

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Regulating mammalian checkpoints through Cdc25 inactivation

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The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an update

1 reference

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Evaluation of antimitotic agents by quantitative comparisons of their effects on the polymerization of purified tubulin

1 reference

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Elevated levels of microtubule destabilizing factors in a Taxol-resistant/dependent A549 cell line with an alpha-tubulin mutation.

1 reference

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Caspases: keys in the ignition of cell death

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Structural basis for the interaction of tubulin with proteins and drugs that affect microtubule dynamics

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Emerging roles of caspase-3 in apoptosis

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Syntheses and antitumor activity of cis-restricted combretastatins: 5-membered heterocyclic analogues

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Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4.

1 reference

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Differential cytotoxicity of combretastatins A1 and A4 in two daunorubicin-resistant P388 cell lines

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Direct C-H arylation and alkenylation of 1-substituted tetrazoles: phosphine as stabilizing factor

1 reference

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Synthesis and evaluation of analogs of (Z)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as potential cytotoxic and antimitotic agents

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Identifiers

10.1021/JM2013979

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

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