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Aldo-keto reductases and formation of polycyclic aromatic hydrocarbon o-quinones.
scientific article published on January 2004
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scholarly article
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stated in
Europe PubMed Central
PMC publication ID
2561330
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15038957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
review article
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Europe PubMed Central
title
Aldo-keto reductases and formation of polycyclic aromatic hydrocarbon o-quinones
(English)
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stated in
Europe PubMed Central
PMC publication ID
2561330
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15038957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
main subject
polycyclic aromatic hydrocarbons
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author
Trevor M Penning
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
2561330
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15038957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
author name string
Trevor M Penning
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1
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Europe PubMed Central
PubMed publication ID
15038957
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9 August 2017
language of work or name
English
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publication date
1 January 2004
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Europe PubMed Central
PMC publication ID
2561330
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15038957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
published in
Methods in Enzymology
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Europe PubMed Central
PMC publication ID
2561330
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15038957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
volume
378
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Europe PubMed Central
PMC publication ID
2561330
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15038957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
page(s)
31-67
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Europe PubMed Central
PMC publication ID
2561330
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15038957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
cites work
Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Conversion of mammalian 3alpha-hydroxysteroid dehydrogenase to 20alpha-hydroxysteroid dehydrogenase using loop chimeras: changing specificity from androgens to progestins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
cDNA cloning, expression and activity of a second human aflatoxin B1-metabolizing member of the aldo-keto reductase superfamily, AKR7A3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Synthesis and characterization of polycyclic aromatic hydrocarbon o-quinone depurinating N7-guanine adducts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Mutagenesis of 3 alpha-hydroxysteroid dehydrogenase reveals a "push-pull" mechanism for proton transfer in aldo-keto reductases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Comparative anatomy of the aldo-keto reductase superfamily
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Steroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Structure of 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase complexed with NADP+
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Cytotoxicity and mutagenicity of polycyclic aromatic hydrocarbon ortho-quinones produced by dihydrodiol dehydrogenase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
An ethoxyquin-inducible aldehyde reductase from rat liver that metabolizes aflatoxin B1 defines a subfamily of aldo-keto reductases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Overexpression and mutagenesis of the cDNA for rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase. Role of cysteines and tyrosines in catalysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Three-dimensional structure of rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase: a member of the aldo-keto reductase superfamily
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Cytotoxicity of polycyclic aromatic hydrocarbon o-quinones in rat and human hepatoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Reactions of oxyl radicals with DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Identification of benzo[a]pyrene-7,8-dione as an authentic metabolite of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene in isolated rat hepatocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Human aldose reductase: rate constants for a mechanism including interconversion of ternary complexes by recombinant wild-type enzyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Central role of radical cations in metabolic activation of polycyclic aromatic hydrocarbons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Radiochemical detection of dihydrodiol dehydrogenase: distribution of the enzyme in male Sprague-Dawley rat tissues and its sensitivity to inhibition by indomethacin and 6-medroxyprogesterone acetate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Regio- and stereospecificity of homogeneous 3 alpha-hydroxysteroid-dihydrodiol dehydrogenase for trans-dihydrodiol metabolites of polycyclic aromatic hydrocarbons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Spectroscopic identification of ortho-quinones as the products of polycyclic aromatic trans-dihydrodiol oxidation catalyzed by dihydrodiol dehydrogenase. A potential route of proximate carcinogen metabolism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Oxidation of the trans-3,4-dihydrodiol metabolites of the potent carcinogen 7,12-dimethylbenz(a)anthracene and other benz(a)anthracene derivatives by 3 alpha-hydroxysteroid-dihydrodiol dehydrogenase: effects of methyl substitution on velocity and st
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Purification and properties of multiple forms of dihydrodiol dehydrogenase from human liver
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
The kinetic mechanism catalysed by homogeneous rat liver 3 alpha-hydroxysteroid dehydrogenase. Evidence for binary and ternary dead-end complexes containing non-steroidal anti-inflammatory drugs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Cloning and sequencing of the cDNA for rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Structural and functional comparison of two human liver dihydrodiol dehydrogenases associated with 3 alpha-hydroxysteroid dehydrogenase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
ras and human tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Polycyclic aromatic hydrocarbon (PAH) ortho-quinone conjugate chemistry: kinetics of thiol addition to PAH ortho-quinones and structures of thioether adducts of naphthalene-1,2-dione
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
The use of acetylated ferricytochrome C for the detection of superoxide radicals produced in biological membranes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Quantitative determination of hemoglobin and cytochemical staining for peroxidase using 3,3′,5,5′-tetramethylbenzidine dihydrochloride, a safe substitute for benzidine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
27 July 2018
Reactive oxygen species generated by PAH o-quinones cause change-in-function mutations in p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
25 September 2018
The ubiquitous aldehyde reductase (AKR1A1) oxidizes proximate carcinogen trans-dihydrodiols to o-quinones: potential role in polycyclic aromatic hydrocarbon activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
25 September 2018
Stable expression of rat dihydrodiol dehydrogenase (AKR1C9) in human breast MCF-7 cells results in the formation of PAH-o-quinones and enzyme mediated cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
25 September 2018
Characterization of enzymes participating in carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human placenta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
25 September 2018
Dihydrodiol dehydrogenases and polycyclic aromatic hydrocarbon activation: generation of reactive and redox active o-quinones.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
25 September 2018
A new nomenclature for the aldo-keto reductase superfamily.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
25 September 2018
Expanded analysis of benzo[a]pyrene-DNA adducts formed in vitro and in mouse skin: their significance in tumor initiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
25 September 2018
Reactivity of benzo[a]pyrene-7,8-dione with DNA. Evidence for the formation of deoxyguanosine adducts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
25 September 2018
Carcinogenic metabolites of 5-methylchrysene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
25 September 2018
Identification and quantitation of benzo[a]pyrene-DNA adducts formed by rat liver microsomes in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561330
retrieved
25 September 2018
The arginine 276 anchor for NADP(H) dictates fluorescence kinetic transients in 3 alpha-hydroxysteroid dehydrogenase, a representative aldo-keto reductase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression and characterization of four recombinant human dihydrodiol dehydrogenase isoforms: oxidation of trans-7, 8-dihydroxy-7,8-dihydrobenzo[a]pyrene to the activated o-quinone metabolite benzo[a]pyrene-7,8-dione
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Benzene Oxide-Oxepin Valence Tautomerism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and tumor-initiating activity in mouse skin of dibenzo[a,l]pyrene syn- and anti-fjord-region diolepoxides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Examination of diols and diol epoxides of polycyclic aromatic hydrocarbons as substrates for rat liver dihydrodiol dehydrogenase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generation of Reactive Oxygen Species during the Enzymatic Oxidation of Polycyclic Aromatic Hydrocarbontrans-Dihydrodiols Catalyzed by Dihydrodiol Dehydrogenase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA strand scission by polycyclic aromatic hydrocarbon o-quinones: role of reactive oxygen species, Cu(II)/Cu(I) redox cycling, and o-semiquinone anion radicals,
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insertion of nucleotides opposite apurinic/apyrimidinic sites in deoxyribonucleic acid during in vitro synthesis: uniqueness of adenine nucleotides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo oxidative DNA damage: measurement of 8-hydroxy-2'-deoxyguanosine in DNA and urine by high-performance liquid chromatography with electrochemical detection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978003-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0076-6879(04)78003-9
1 reference
stated in
Europe PubMed Central
PMC publication ID
2561330
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15038957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
PMC publication ID
2561330
1 reference
stated in
Europe PubMed Central
PMC publication ID
2561330
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15038957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
PubMed publication ID
15038957
1 reference
stated in
Europe PubMed Central
PMC publication ID
2561330
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15038957%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
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