(Q35709076)

9 August 2017

title

Critical role for phosphoinositide 3-kinase gamma in parasite invasion and disease progression of cutaneous leishmaniasis (English)

1 reference

geographic parasite invasion

9 August 2017

main subject

1 reference

14

Danuta Radzioch

1 reference

9 August 2017

Patrick Reville

3

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author name string

Hannah E Cummings

1

1 reference

9 August 2017

Joseph Barbi

2

1 reference

9 August 2017

Steve Oghumu

4

1 reference

9 August 2017

Nicholas Zorko

5

1 reference

9 August 2017

Anasuya Sarkar

6

1 reference

9 August 2017

Tracy L Keiser

7

1 reference

9 August 2017

Bao Lu

8

1 reference

9 August 2017

Thomas Rückle

9

1 reference

9 August 2017

Sanjay Varikuti

10

1 reference

9 August 2017

Claudio Lezama-Davila

11

1 reference

9 August 2017

Mark D Wewers

12

1 reference

9 August 2017

Caroline Whitacre

13

1 reference

9 August 2017

Christian Rommel

15

1 reference

9 August 2017

Stéphanie Seveau

16

1 reference

9 August 2017

Abhay R Satoskar

17

1 reference

9 August 2017

language of work or name

English

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publication date

9 January 2012

1 reference

9 August 2017

number of pages

6

1 reference

full work available at URL

inferred from page(s)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268302

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published in

Proceedings of the National Academy of Sciences of the United States of America

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9 August 2017

volume

109

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9 August 2017

issue

4

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9 August 2017

page(s)

1251-1256

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maintained by WikiProject

9 August 2017

WikiProject Invasion Biology

1 reference

Discovery of dual inhibitors of the immune cell PI3Ks p110delta and p110gamma: a prototype for new anti-inflammatory drugs

inferred from title

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

In vivo imaging reveals an essential role for neutrophils in leishmaniasis transmitted by sand flies.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Host-directed drug targeting of factors hijacked by pathogens

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Phosphoinositide 3-kinase gamma inhibition plays a crucial role in early steps of inflammation by blocking neutrophil recruitment

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Differential association of phosphatidylinositol 3-kinase, SHIP-1, and PTEN with forming phagosomes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

PI3Kgamma inhibition: towards an 'aspirin of the 21st century'?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Essential role of PI3Kdelta and PI3Kgamma in thymocyte survival

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Phosphoinositide 3-kinase: diverse roles in immune cell activation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Neutrophil granulocytes--Trojan horses for Leishmania major and other intracellular microbes?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Evasion of innate immunity by parasitic protozoa

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Phosphoinositide 3-kinases in immunity: lessons from knockout mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Intracellular survival of Leishmania major in neutrophil granulocytes after uptake in the absence of heat-labile serum factors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Trypanosoma cruzi: phosphatidylinositol 3-kinase and protein kinase B activation is associated with parasite invasion

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Molecular mechanisms that confer antibacterial drug resistance

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Leishmania species: models of intracellular parasitism.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

The p110delta isoform of phosphatidylinositol 3-kinase controls susceptibility to Leishmania major by regulating expansion and tissue homing of regulatory T cells.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

The biology and future prospects of antivirulence therapies

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Genetic background influences immune responses and disease outcome of cutaneous L. mexicana infection in mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

The proteasome inhibitor MLN-273 blocks exoerythrocytic and erythrocytic development of Plasmodium parasites

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Novel PI 3-kinase-dependent mechanisms of trypanosome invasion and vacuole maturation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

CC chemokine receptor (CCR)2 is required for langerhans cell migration and localization of T helper cell type 1 (Th1)-inducing dendritic cells. Absence of CCR2 shifts the Leishmania major-resistant phenotype to a susceptible state dominated by Th2 c

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268302

Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma

25 September 2018

1 reference

12 December 2020

Activation of host cell phosphatidylinositol 3-kinases by Trypanosoma cruzi infection

1 reference

12 December 2020

Leishmania-induced cellular recruitment during the early inflammatory response: modulation of proinflammatory mediators

1 reference

12 December 2020

The formation of a structure with the features of synovial lining by subcutaneous injection of air: an in vivo tissue culture system

1 reference

12 December 2020

Cutting edge: neutrophil granulocyte serves as a vector for Leishmania entry into macrophages

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1110339109

1 reference

9 August 2017

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1 reference

9 August 2017

1 reference