(Q35715619)

9 August 2017

title

DHA and EPA reverse cystic fibrosis-related FA abnormalities by suppressing FA desaturase expression and activity (English)

1 reference

9 August 2017

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Sarah W Njoroge

1

1 reference

9 August 2017

Michael Laposata

series ordinal

2

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9 August 2017

Waddah Katrangi

series ordinal

3

1 reference

9 August 2017

Adam C Seegmiller

series ordinal

4

1 reference

9 August 2017

publication date

16 November 2011

1 reference

Journal of Lipid Research

9 August 2017

published in

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9 August 2017

volume

53

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9 August 2017

issue

2

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9 August 2017

page(s)

257-265

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Increased Δ5- and Δ6-desaturase, cyclooxygenase-2, and lipoxygenase-5 expression and activity are associated with fatty acid and eicosanoid changes in cystic fibrosis

9 August 2017

cites work

1 reference

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Increased elongase 6 and Δ9-desaturase activity are associated with n-7 and n-9 fatty acid changes in cystic fibrosis

12 July 2018

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Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century

12 July 2018

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Plasma lipidomics reveals potential prognostic signatures within a cohort of cystic fibrosis patients.

12 July 2018

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Fatty acid metabolism in cystic fibrosis

12 July 2018

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Linoleic acid supplementation results in increased arachidonic acid and eicosanoid production in CF airway cells and in cftr-/- transgenic mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

CFTR depletion results in changes in fatty acid composition and promotes lipogenesis in intestinal Caco 2/15 cells

12 July 2018

1 reference

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Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease

12 July 2018

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Fatty acid supplements improve respiratory, inflammatory and nutritional parameters in adults with cystic fibrosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Enteric circular muscle dysfunction in the cystic fibrosis mouse small intestine

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Influence of the cystic fibrosis transmembrane conductance regulator on expression of lipid metabolism-related genes in dendritic cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Serum linoleic acid status as a clinical indicator of essential fatty acid status in children with cystic fibrosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Cystic fibrosis and nutrition: linking phospholipids and essential fatty acids with thiol metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

A mechanism accounting for the low cellular level of linoleic acid in cystic fibrosis and its reversal by DHA.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Cell culture models demonstrate that CFTR dysfunction leads to defective fatty acid composition and metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Docosahexaenoic acid (DHA) and hepatic gene transcription

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Relation between fatty acid composition and clinical status or genotype in cystic fibrosis patients

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Fatty acid alterations and n-3 fatty acid supplementation in cystic fibrosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Peroxisome proliferator-activated receptor alpha (PPAR alpha) down-regulation in cystic fibrosis lymphocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Fatty acid elongases in mammals: their regulation and roles in metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Fatty acid regulation of hepatic gene transcription.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

A simple method for the isolation and purification of total lipides from animal tissues

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Essential fatty acid synthesis and its regulation in mammals

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Gene regulation of mammalian desaturases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Pseudomonas aeruginosa induction of apoptosis in respiratory epithelial cells: analysis of the effects of cystic fibrosis transmembrane conductance regulator dysfunction and bacterial virulence factors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr(-/-) mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Differential stimulation of cytosolic phospholipase A2 by bradykinin in human cystic fibrosis cell lines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Cystic Fibrosis Gene Mutation (ΔF508) Is Associated with an Intrinsic Abnormality in Ca2+-Induced Arachidonic Acid Release by Epithelial Cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Increase of bradykinin-stimulated arachidonic acid release in a ΔF508 cystic fibrosis epithelial cell line

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Pathological regulation of arachidonic acid release in cystic fibrosis: the putative basic defect

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Identification of the cystic fibrosis gene: genetic analysis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Leukotrienes in the sputum and urine of cystic fibrosis children

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Peroxisomal retroconversion of docosahexaenoic acid (22:6(n−3)) to eicosapentaenoic acid (20:5(n−3)) studied in isolated rat liver cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

12 July 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M018101

Essential fatty acid deficiency in relation to genotype in patients with cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M018101

Serum phospholipid fatty acid profile and dietary intake in an adult Mediterranean population with cystic fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M018101

Cystic fibrosis fatty acid imbalance is linked to ceramide deficiency and corrected by fenretinide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M018101

Characterization of LPS-induced lung inflammation in cftr-/- mice and the effect of docosahexaenoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M018101

Bioavailability and safety of a high dose of docosahexaenoic acid triacylglycerol of algal origin in cystic fibrosis patients: a randomized, controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M018101

Fatty acids in blood and intestine following docosahexaenoic acid supplementation in adults with cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M018101

Oral DHA supplementation in DeltaF508 homozygous cystic fibrosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M018101

Effect of an 8-month treatment with omega-3 fatty acids (eicosapentaenoic and docosahexaenoic) in patients with cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M018101

Biological effects of a dietary omega-3 polyunsaturated fatty acids supplementation in cystic fibrosis patients: a randomized, crossover placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M018101

Identification of primula fatty acid delta 6-desaturases with n-3 substrate preferences

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M018101

Altered eicosanoid metabolism in the cystic fibrosis mouse small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M018101

Differential eicosapentaenoic acid elevations and altered cardiovascular disease risk factor responses after supplementation with docosahexaenoic acid in postmenopausal women receiving and not receiving hormone replacement therapy

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Increased tissue arachidonic acid and reduced linoleic acid in a mouse model of cystic fibrosis are reversed by supplemental glycerophospholipids enriched in docosahexaenoic acid

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269161

Evidence of increased flux to n-6 docosapentaenoic acid in phospholipids of pancreas from cftr-/- knockout mice

25 September 2018

1 reference

12 December 2020

Differential incorporation of fatty acids into and peroxidative loss of fatty acids from phospholipids of human spermatozoa

1 reference

12 December 2020

The deltaF508 mutation in the cystic fibrosis transmembrane conductance regulator alters control of essential fatty acid utilization in epithelial cells

1 reference

12 December 2020

Prostaglandins E2 and E2 alpha are elevated in saliva of cystic fibrosis patients

1 reference

12 December 2020

Leukotriene B4 markedly elevated in the epithelial lining fluid of patients with cystic fibrosis

1 reference

12 December 2020

Eicosapentaenoic acid modulates neutrophil leukotriene B4 receptor expression in cystic fibrosis

1 reference

12 December 2020

The absorption and effect of dietary supplementation with omega-3 fatty acids on serum leukotriene B4 in patients with cystic fibrosis

1 reference

12 December 2020

Retroconversion and metabolism of [13C]22:6n-3 in humans and rats after intake of a single dose of [13C]22:6n-3-triacylglycerols

1 reference

12 December 2020

Prostanoid biosynthesis in patients with cystic fibrosis

1 reference

12 December 2020

Dietary docosahexaenoic acid as a source of eicosapentaenoic acid in vegetarians and omnivores

1 reference

12 December 2020

Decreased peroxisome proliferator activated receptor alpha is associated with bile duct injury in cystic fibrosis transmembrane conductance regulator-/- mice

1 reference

12 December 2020

Identifiers

DOI

10.1194/JLR.M018101

1 reference

9 August 2017

1 reference

9 August 2017

1 reference