(Q35723413)

9 August 2017

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title

Biosynthesis, transport, and modification of lipid A. (English)

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9 August 2017

M Stephen Trent

1

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9 August 2017

1 February 2004

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Biochemistry and Cell Biology

9 August 2017

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9 August 2017

82

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9 August 2017

71-86

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9 August 2017

1

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Toll-like receptors in the induction of the innate immune response

9 August 2017

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Basic local alignment search tool

21 January 2018

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

21 January 2018

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Novel variation of lipid A structures in strains of different Yersinia species

21 January 2018

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Ligand-selective modulation of the permeability transition pore by arginine modification. Opposing effects of p-hydroxyphenylglyoxal and phenylglyoxal.

21 January 2018

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The Salmonella typhi melittin resistance gene pqaB affects intracellular growth in PMA-differentiated U937 cells, polymyxin B resistance and lipopolysaccharide.

21 January 2018

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Inhibition of lipopolysaccharide biosynthesis and cell growth following inactivation of the kdtA gene in Escherichia coli

21 January 2018

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Pathogenic Yersinia enterocolitica strains increase the outer membrane permeability in response to environmental stimuli by modulating lipopolysaccharide fluidity and lipid A structure

21 January 2018

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Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria

21 January 2018

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Comparative analyses of secondary gene products of 3-deoxy-D-manno-oct-2-ulosonic acid transferases from Chlamydiaceae in Escherichia coli K-12.

21 January 2018

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3-Deoxy-D-manno-oct-2-ulosonic acid (Kdo) transferase (WaaA) and kdo kinase (KdkA) of Haemophilus influenzae are both required to complement a waaA knockout mutation of Escherichia coli

21 January 2018

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Oxidative decarboxylation of UDP-glucuronic acid in extracts of polymyxin-resistant Escherichia coli. Origin of lipid a species modified with 4-amino-4-deoxy-L-arabinose

21 January 2018

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Origin of lipid A species modified with 4-amino-4-deoxy-L-arabinose in polymyxin-resistant mutants of Escherichia coli. An aminotransferase (ArnB) that generates UDP-4-deoxyl-L-arabinose

21 January 2018

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The dolichol pathway of N-linked glycosylation

21 January 2018

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Effect of cold shock on lipid A biosynthesis in Escherichia coli. Induction At 12 degrees C of an acyltransferase specific for palmitoleoyl-acyl carrier protein.

21 January 2018

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Fe(III)-mediated cellular toxicity

21 January 2018

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Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog in a closed conformation

21 January 2018

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Function of the htrB high temperature requirement gene of Escherichia coli in the acylation of lipid A: HtrB catalyzed incorporation of laurate

21 January 2018

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Function of the Escherichia coli msbB gene, a multicopy suppressor of htrB knockouts, in the acylation of lipid A. Acylation by MsbB follows laurate incorporation by HtrB.

21 January 2018

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Structure of the LpxC deacetylase with a bound substrate-analog inhibitor.

21 January 2018

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First committed step of lipid A biosynthesis in Escherichia coli: sequence of the lpxA gene

21 January 2018

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Phosphorylation of the Lipid A Region of Meningococcal Lipopolysaccharide: Identification of a Family of Transferases That Add Phosphoethanolamine to Lipopolysaccharide

21 January 2018

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Dendritic cell activation and cytokine production induced by group B Neisseria meningitidis: interleukin-12 production depends on lipopolysaccharide expression in intact bacteria.

21 January 2018

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ATPase activity of the MsbA lipid flippase of Escherichia coli

21 January 2018

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An Escherichia coli mutant defective in lipid export

21 January 2018

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The Neisseria gonorrhoeae lpxLII gene encodes for a late-functioning lauroyl acyl transferase, and a null mutation within the gene has a significant effect on the induction of acute inflammatory responses

21 January 2018

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Regulation of blood coagulation

21 January 2018

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Overexpression of the waaZ gene leads to modification of the structure of the inner core region of Escherichia coli lipopolysaccharide, truncation of the outer core, and reduction of the amount of O polysaccharide on the cell surface

21 January 2018

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Identification of the gene encoding the Escherichia coli lipid A 4'-kinase. Facile phosphorylation of endotoxin analogs with recombinant LpxK.

21 January 2018

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Oxygen requirement for the biosynthesis of the S-2-hydroxymyristate moiety in Salmonella typhimurium lipid A. Function of LpxO, A new Fe2+/alpha-ketoglutarate-dependent dioxygenase homologue

21 January 2018

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Analysis of lipopolysaccharide biosynthesis in Salmonella typhimurium and Escherichia coli by using agents which specifically block incorporation of 3-deoxy-D-manno-octulosonate

21 January 2018

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PhoP-PhoQ activates transcription of pmrAB, encoding a two-component regulatory system involved in Salmonella typhimurium antimicrobial peptide resistance

21 January 2018

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PmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A modification and polymyxin resistance.

21 January 2018

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Genetic and functional analysis of a PmrA-PmrB-regulated locus necessary for lipopolysaccharide modification, antimicrobial peptide resistance, and oral virulence of Salmonella enterica serovar typhimurium

21 January 2018

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Lipid A acylation and bacterial resistance against vertebrate antimicrobial peptides.

21 January 2018

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The assembly system for the outer core portion of R1- and R4-type lipopolysaccharides of Escherichia coli. The R1 core-specific beta-glucosyltransferase provides a novel attachment site for O-polysaccharides.

21 January 2018

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Increased substitution of phosphate groups in lipopolysaccharides and lipid A of the polymyxin-resistant pmrA mutants of Salmonella typhimurium: a 31P-NMR study.

21 January 2018

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Cloning, expression, and purification of UDP-3-O-acyl-GlcNAc deacetylase from Pseudomonas aeruginosa: a metalloamidase of the lipid A biosynthesis pathway

21 January 2018

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UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase of Escherichia coli is a zinc metalloenzyme

21 January 2018

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Site-directed mutagenesis of the bacterial metalloamidase UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC). Identification of the zinc binding site

21 January 2018

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Ca2+-induced phosphoethanolamine transfer to the outer 3-deoxy-D-manno-octulosonic acid moiety of Escherichia coli lipopolysaccharide. A novel membrane enzyme dependent upon phosphatidylethanolamine

21 January 2018

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Molecular diversity of the genetic loci responsible for lipopolysaccharide core oligosaccharide assembly within the genus Salmonella

21 January 2018

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Expression cloning and biochemical characterization of a Rhizobium leguminosarum lipid A 1-phosphatase

21 January 2018

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Complex phenotypes of null mutations in the htr genes, whose products are essential for Escherichia coli growth at elevated temperatures

21 January 2018

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The lethal phenotype caused by null mutations in the Escherichia coli htrB gene is suppressed by mutations in the accBC operon, encoding two subunits of acetyl coenzyme A carboxylase

21 January 2018

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Closing the loop: the PmrA/PmrB two-component system negatively controls expression of its posttranscriptional activator PmrD.

21 January 2018

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A lethal role for lipid A in Salmonella infections.

21 January 2018

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Potent, novel in vitro inhibitors of the Pseudomonas aeruginosa deacetylase LpxC.

21 January 2018

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A small protein that mediates the activation of a two-component system by another two-component system

21 January 2018

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Molecular analysis of prenyl chain elongating enzymes

21 January 2018

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Structural characterization of the lipid A component of pathogenic Neisseria meningitidis

21 January 2018

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Structural study on the free lipid A isolated from lipopolysaccharide of Porphyromonas gingivalis

21 January 2018

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The cytoplasmic tail of the G-protein-coupled receptor for parathyroid hormone and parathyroid hormone-related protein contains positive and negative signals for endocytosis

21 January 2018

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Synthesis of a carbohydrate-derived hydroxamic acid inhibitor of the bacterial enzyme (LpxC) involved in lipid A biosynthesis.

21 January 2018

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Identification of a gene (lpt-3) required for the addition of phosphoethanolamine to the lipopolysaccharide inner core of Neisseria meningitidis and its role in mediating susceptibility to bactericidal killing and opsonophagocytosis

21 January 2018

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An ancient system of host defense

21 January 2018

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21 January 2018

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Endotoxin biosynthesis in Pseudomonas aeruginosa: enzymatic incorporation of laurate before 3-deoxy-D-manno-octulosonate

21 January 2018

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Structural characterization of the lipid A component of Helicobacter pylori rough- and smooth-form lipopolysaccharides

21 January 2018

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Lipopolysaccharides of polymyxin B-resistant mutants of Escherichia coli are extensively substituted by 2-aminoethyl pyrophosphate and contain aminoarabinose in lipid A.

21 January 2018

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Shortened hydroxyacyl chains on lipid A of Escherichia coli cells expressing a foreign UDP-N-acetylglucosamine O-acyltransferase.

21 January 2018

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Pathogenetic mechanisms of septic shock

21 January 2018

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Crystallization of UDP-N-acetylglucosamine O-acyltransferase from Escherichia coli.

21 January 2018

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Inhibition of the antibacterial target UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC): isoxazoline zinc amidase inhibitors bearing diverse metal binding groups

21 January 2018

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High-throughput catch-and-release synthesis of oxazoline hydroxamates. Structure-activity relationships in novel inhibitors of Escherichia coli LpxC: in vitro enzyme inhibition and antibacterial properties

21 January 2018

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Mutational analysis and properties of the msbA gene of Escherichia coli, coding for an essential ABC family transporter

21 January 2018

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Intracellular survival of Neisseria gonorrhoeae in male urethral epithelial cells: importance of a hexaacyl lipid A

21 January 2018

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Bordetella bronchiseptica PagP is a Bvg‐regulated lipid A palmitoyl transferase that is required for persistent colonization of the mouse respiratory tract

21 January 2018

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Biochemistry of endotoxins

21 January 2018

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Lipopolysaccharide endotoxins

21 January 2018

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The ATP binding cassette multidrug transporter LmrA and lipid transporter MsbA have overlapping substrate specificities

21 January 2018

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Identification of Legionella pneumophila rcp, a pagP-like gene that confers resistance to cationic antimicrobial peptides and promotes intracellular infection

21 January 2018

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Two-component regulatory systems can interact to process multiple environmental signals

21 January 2018

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Outer membrane composition of a lipopolysaccharide-deficient Neisseria meningitidis mutant

21 January 2018

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Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen

21 January 2018

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Chemical structure and biological activity of a lipid A component from Helicobacter pylori strain 206.

21 January 2018

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Acylation of the lipooligosaccharide of Haemophilus influenzae and colonization: an htrB mutation diminishes the colonization of human airway epithelial cells.

21 January 2018

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The COG database: a tool for genome-scale analysis of protein functions and evolution

21 January 2018

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The COG database: new developments in phylogenetic classification of proteins from complete genomes

21 January 2018

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Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum

21 January 2018

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A PhoP/PhoQ-induced Lipase (PagL) that catalyzes 3-O-deacylation of lipid A precursors in membranes of Salmonella typhimurium

21 January 2018

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Endotoxin of Neisseria meningitidis composed only of intact lipid A: inactivation of the meningococcal 3-deoxy-D-manno-octulosonic acid transferase.

21 January 2018

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Recognition of gram-negative bacteria and endotoxin by the innate immune system

21 January 2018

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Antibiotic-supersusceptible mutants of Escherichia coli and Salmonella typhimurium

21 January 2018

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Characterization of the lipopolysaccharide from the polymyxin-resistantpmrAmutants ofSalmonella typhimurium

21 January 2018

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Update on meningococcal disease with emphasis on pathogenesis and clinical management

21 January 2018

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Structural analysis of Francisella tularensis lipopolysaccharide.

21 January 2018

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Structural characterization of the lipid A component of Bacteroides fragilis strain NCTC 9343 lipopolysaccharide

21 January 2018

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Biosynthesis of lipopolysaccharide O antigens

21 January 2018

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Crystal structure of LpxC, a zinc-dependent deacetylase essential for endotoxin biosynthesis

21 January 2018

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Acyl-acyl carrier protein specificity of UDP-GlcNAc acyltransferases from gram-negative bacteria: relationship to lipid A structure

21 January 2018

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A signal transduction system that responds to extracellular iron.

21 January 2018

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Structural elucidation and monokine-inducing activity of two biologically active zwitterionic glycosphingolipids derived from the porcine parasitic nematode Ascaris suum

21 January 2018

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The human copper-zinc superoxide dismutase gene (SOD1) proximal promoter is regulated by Sp1, Egr-1, and WT1 via non-canonical binding sites

21 January 2018

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Meningitis bacterium is viable without endotoxin

21 January 2018

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RETRACTED: Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters

21 January 2018

1 reference

12 January 2024

https://opencitations.net/index/api/v1/citations/10.1126/SCIENCE.293.5536.1793

Identifiers

DOI

10.1139/O03-070

1 reference

release_c3lj34hxdbgqznmmd654fgj45u

9 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/c3lj34hxdbgqznmmd654fgj45u

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

15052329

1 reference

PubMed ID

15052329