(Q33857528)

29 July 2017

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title

Regulation of blood coagulation (English)

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29 July 2017

C T Esmon

1

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29 July 2017

language of work or name

English

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publication date

1 March 2000

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29 July 2017

number of pages

12

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Biochimica et Biophysica Acta

inferred from page(s)

published in

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29 July 2017

volume

1477

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29 July 2017

issue

1-2

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29 July 2017

page(s)

349-360

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Interaction of calcium with bovine plasma protein C

29 July 2017

cites work

1 reference

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7 January 2021

Binding of the bovine basic pancreatic trypsin inhibitor (Kunitz) to human alpha-, beta- and gamma-thrombin; a kinetic and thermodynamic study

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7 January 2021

TAFI, or plasma procarboxypeptidase B, couples the coagulation and fibrinolytic cascades through the thrombin-thrombomodulin complex

1 reference

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7 January 2021

Both cellular and soluble forms of thrombomodulin inhibit fibrinolysis by potentiating the activation of thrombin-activable fibrinolysis inhibitor

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7 January 2021

Enhanced protein C activation and inhibition of fibrinogen cleavage by a thrombin modulator

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7 January 2021

Mutation in blood coagulation factor V associated with resistance to activated protein C.

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7 January 2021

The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

1 reference

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7 January 2021

Inherited protein C deficiency and coumarin-responsive chronic relapsing purpura fulminans in a newborn infant

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Human protein C and activated protein C Components of the human anticoagulation system

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Hydrophobic amino acid residues of human anticoagulation protein C that contribute to its functional binding to phospholipid Vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Tumor necrosis factor suppresses transcription of the thrombomodulin gene in endothelial cells

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Physiological anticoagulation. Resistance to activated protein C and venous thromboembolism

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Rational engineering of activity and specificity in a serine protease

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Allosteric modulation of BPTI interaction with human alpha- and zeta-thrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Acceleration of the thrombin inactivation of single chain urokinase-type plasminogen activator (pro-urokinase) by thrombomodulin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Molecular mechanisms of thrombin function

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Treatment of homozygous protein C deficiency and neonatal purpura fulminans with a purified protein C concentrate

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

The effect of Arg306-->Ala and Arg506-->Gln substitutions in the inactivation of recombinant human factor Va by activated protein C and protein S.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

The endothelial cell protein C receptor. Cell surface expression and direct ligand binding by the soluble receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Activation mechanism of anticoagulant protein C in large blood vessels involving the endothelial cell protein C receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Mutation of protease domain residues Lys37-39 in human protein C inhibits activation by the thrombomodulin-thrombin complex without affecting activation by free thrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Conversion of thrombin into an anticoagulant by protein engineering

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

The effects of recombinant human thrombomodulin on endotoxin-induced multiple-system organ failure in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Influence of Arginines 93, 97, and 101 of thrombin to its functional specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Thrombomodulin gene mutations associated with myocardial infarction.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Human plasma protein C: isolation, characterization, and mechanism of activation by alpha-thrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Anticoagulant properties of bovine plasma protein C following activation by thrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Activation of thrombin-activable fibrinolysis inhibitor requires epidermal growth factor-like domain 3 of thrombomodulin and is inhibited competitively by protein C.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Different glycoforms of human thrombomodulin. Their glycosaminoglycan-dependent modulatory effects on thrombin inactivation by heparin cofactor II and antithrombin III

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Human protein C receptor is present primarily on endothelium of large blood vessels: implications for the control of the protein C pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Glu-192----Gln substitution in thrombin mimics the catalytic switch induced by thrombomodulin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Lupus anticoagulant and protein S deficiency in children with postvaricella purpura fulminans or thrombosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Activated protein C cleavage of factor Va leads to dissociation of the A2 domain

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Increased risk of venous thrombosis in carriers of natural anticoagulant deficiencies. Results of the family studies of the Spanish Multicenter Study on Thrombophilia (EMET study).

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

The 2.8 A crystal structure of Gla-domainless activated protein C

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Acquired APC resistance related to oral contraceptives and pregnancy and its possible implications for clinical practice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Absence of thrombosis in subjects with heterozygous protein C deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Clinical features of thrombophilia in families with gene defects in protein C or protein S combined with factor V Leiden.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Modulation of endothelial cell hemostatic properties by tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Peptide bond cleavages and loss of functional activity during inactivation of factor Va and factor VaR506Q by activated protein C.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Calcium-dependence of the interactions between protein C, thrombin and the elastase fragment of thrombomodulin. Analysis by ultracentrifugation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

The ternary microplasmin-staphylokinase-microplasmin complex is a proteinase-cofactor-substrate complex in action

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Anticoagulant synergism of heparin and activated protein C in vitro. Role of a novel anticoagulant mechanism of heparin, enhancement of inactivation of factor V by activated protein C

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Purpura fulminans in meningococcemia: association with acquired deficiencies of proteins C and S.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

The interaction between the endothelial cell protein C receptor and protein C is dictated by the gamma-carboxyglutamic acid domain of protein C.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

The FcgammaRII receptor triggers pp125FAK phosphorylation in platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Protein C Inhibitor Is a Potent Inhibitor of the Thrombin-Thrombomodulin Complex

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Thrombomodulin increases the rate of thrombin inhibition by BPTI

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Enhancing protein C interaction with thrombin results in a clot-activated anticoagulant

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein C

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Homozygous protein C deficiency manifested by massive venous thrombosis in the newborn

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Clarification of the Risk for Venous Thrombosis Associated with Hereditary Protein S Deficiency by Investigation of a Large Kindred with a Characterized Gene Defect

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

A chimeric protein C containing the prothrombin Gla domain exhibits increased anticoagulant activity and altered phospholipid specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

On the role of phosphatidylethanolamine in the inhibition of activated protein C activity by antiphospholipid antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Use of protein-C concentrate, heparin, and haemodiafiltration in meningococcus-induced purpura fulminans

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

A player of many parts: the spotlight falls on thrombin's structure.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Genetic analysis of a large kindred exhibiting type I protein C deficiency and associated thrombosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Active site and exosite binding of alpha-thrombin.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

The thrombin E192Q-BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

A monoclonal antibody recognizing the activation domain of protein C in its calcium-free conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Energetics of thrombin-thrombomodulin interaction.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Crystal structure of the catalytic domain of human plasmin complexed with streptokinase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Single amino acid substitutions dissociate fibrinogen-clotting and thrombomodulin-binding activities of human thrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Reconstitution of the human endothelial cell protein C receptor with thrombomodulin in phosphatidylcholine vesicles enhances protein C activation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Relocating the active site of activated protein C eliminates the need for its protein S cofactor. A fluorescence resonance energy transfer study

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

Protein S alters the active site location of activated protein C above the membrane surface. A fluorescence resonance energy transfer study of topography

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900266-6

7 January 2021

10.1016/S0167-4838(99)00266-6

Identifiers

DOI

1 reference

29 July 2017

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